The Role of Endoscopic Ultrasonography for Localization of Insulinomas without a Pancreatic Lesion on Magnetic Resonance Imaging: A Short Series and Literature Review

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dc.authorid0000-0001-8084-848X
dc.authorid0000-0001-5584-4954
dc.authorscopusid36656843500
dc.authorscopusid55753696900
dc.authorscopusid36926020100
dc.authorscopusid6602931568
dc.authorscopusid35517398400
dc.authorwosidZuhur, Sayid/AAC-6839-2020
dc.authorwosidErdamar, Sibel/X-5511-2018
dc.authorwosidÖztürk, Feyza Yener/AAL-3013-2020
dc.contributor.authorZuhur, Sayid Shafi
dc.contributor.authorKuzu, İdris
dc.contributor.authorÖztürk, Feyza Yener
dc.contributor.authorErdamar, Sibel
dc.contributor.authorAltuntaş, Yüksel
dc.date.accessioned2022-05-11T14:39:53Z
dc.date.available2022-05-11T14:39:53Z
dc.date.issued2015
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractInsulinoma is a rare neuroendocrine tumor of the pancreas and is the most common cause of endogenous hyperinsulinemic hypoglycemia. Although 90% of insulinomas are benign tumors, recurrent episodes of hypoglycemia may lead to life-threatening consequences. Since surgery is the only curative method for patients with insulinomas, the preoperative localization of these tumors by appropriate imaging methods is important. In this case series, we report 5 patients with endogenous hyperinsulinemic hypoglycemia, including one with MEN-1 syndrome, who were diagnosed with insulinoma according to the prolonged fasting test. All patients had normal pancreas on upper abdominal magnetic resonance imaging (MRI), therefore, they underwent endoscopic ultrasonography (EUS) for localization of the insulinomas and were operated according to the EUS results. EUS demonstrated well-demarcated tumors in the tail of the pancreas in 4 subjects and in the head of the pancreas in one patient. However, in contrast to EUS results, one patient with MEN-1 syndrome had a glucagonoma and two insulinomas and one patient had not any tumor on histopathological evaluation of the distal pancreas after surgery. In this case series, we aimed to present the diagnostic performance of EUS and the treatment outcomes in a cluster of patients with insulinomas who had not a pancreatic lesion on upper abdominal MRI and to briefly review the currently available imaging methods for localization of insulinomas.
dc.identifier.doi10.4274/tjem.3007
dc.identifier.endpage98
dc.identifier.issn1301-2193
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84943378117
dc.identifier.scopusqualityQ4
dc.identifier.startpage93
dc.identifier.urihttps://doi.org/10.4274/tjem.3007
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8784
dc.identifier.volume19
dc.identifier.wosWOS:000362601700005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorZuhur, Sayid Shafi
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofTurkish Journal of Endocrinology and Metabolism
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectInsulinoma
dc.subjectMEN-1 syndrome
dc.subjectsporadic
dc.subjectendoscopic ultrasonography
dc.subjectIntraarterial Calcium Stimulation
dc.subjectIslet-Cell Tumors
dc.subjectManagement
dc.subjectUltrasound
dc.subjectEndocrine
dc.subjectDiagnosis
dc.subjectCt
dc.titleThe Role of Endoscopic Ultrasonography for Localization of Insulinomas without a Pancreatic Lesion on Magnetic Resonance Imaging: A Short Series and Literature Review
dc.title.alternativeMagnetik rezonans görüntülemede pankresta lezyon saptanmayan insülinomaların lokalizasyonunda endoskopik ultrasonografinin rolü: Olgu serisi ve literatür derlemesi]
dc.typeReview Article

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