Synthesis of dipyrrolo[2,3-a:1 ',2 ',3 '-fg]acridin-12(1H)-ones
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Erişim
info:eu-repo/semantics/closedAccessTarih
2018Yazar
Beyer, Renee L.Kandemir, Hakan
Bhadbhade, Mohan
Şengül, İbrahim Fazıl
Leu, Chao-Wei
Wenholz, Daniel S.
Black, David StC.
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Acylation reactions of 4,6-dimethoxyindoles with glyoxyloyl chlorides were achieved by the use of graphite powder in 1,2-dichloroethane at reflux. The products were monoketones as a result of decarbonylation, rather than the expected 1,2-diketones. Treatment of these monoketones with base led to their cyclisation and elimination of methanol to afford the novel dipyrrolo[2.3-a:1',2',3'-fg]acridin-12(1H)-ones. (C) 2018 Elsevier Ltd. All rights reserved.