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An ITO Based Disposable Biosensor for Ultrasensitive Analysis of Retinol Binding Protein

dc.contributor.authorSayıklı Şimşek, Çiğdem
dc.contributor.authorTeke, Mustafa
dc.contributor.authorSezgintürk, Mustafa Kemal
dc.date.accessioned2022-05-11T14:29:53Z
dc.date.available2022-05-11T14:29:53Z
dc.date.issued2014
dc.identifier.issn1040-0397
dc.identifier.issn1521-4109
dc.identifier.urihttps://doi.org/10.1002/elan.201300443
dc.identifier.urihttps://hdl.handle.net/20.500.11776/7162
dc.description.abstractA highly sensitive electrochemical biosensor based on anti-RBP biorecognition capable to analyze concentrations of retinol binding protein (RBP) was developed. The construction of the biosensor interfaces was carefully characterized by techniques such as electrochemistry, EIS, and scanning electron microscopy. In order to characterize impedance data, Kramers-Kronig Transform was performed on the experimental impedance data. Besides, for an immunosensor system the Single Frequency Impedance technique was firstly used for the characterization of the interaction between RBP and anti-RBP. Finally, artificial serum samples spiked with RBP were analyzed by the proposed ITO based immunosensor to investigate the usefulness of the biosensor for early biomarker diagnosis.en_US
dc.description.sponsorshipTUBITAK (The Scientific and Technological Research Council of Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [109 T 172]; Namik Kemal University Scientific Research Projects FundNamik Kemal University [NKU-BAP.00.10.YL.13.03]; Namik Kemal University Scientific and Technological Research CenterNamik Kemal University; Mugla Sitki Kocman University Scientific Research Projects FundMugla Sitki Kocman University [12/137]en_US
dc.description.sponsorshipThe financial supports from TUBITAK (The Scientific and Technological Research Council of Turkey, Project number: 109 T 172), Namik Kemal University Scientific Research Projects Fund (Project Number: NKU-BAP.00.10.YL.13.03), Namik Kemal University Scientific and Technological Research Center, and Mugla Sitki Kocman University Scientific Research Projects Fund (Project number: 12/137) are gratefully acknowledged.en_US
dc.language.isoengen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.identifier.doi10.1002/elan.201300443
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRetinol binding proteinen_US
dc.subjectITOen_US
dc.subjectSingle frequency impedanceen_US
dc.subjectBiosensoren_US
dc.subjectBiomarkeren_US
dc.subjectIndium-Tin Oxideen_US
dc.subjectVitamin-Aen_US
dc.subjectSurrogate Measureen_US
dc.subjectElectrodesen_US
dc.subjectCatecholamineen_US
dc.subjectChildrenen_US
dc.subjectKidneyen_US
dc.titleAn ITO Based Disposable Biosensor for Ultrasensitive Analysis of Retinol Binding Proteinen_US
dc.typearticleen_US
dc.relation.ispartofElectroanalysisen_US
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümüen_US
dc.identifier.volume26en_US
dc.identifier.issue2en_US
dc.identifier.startpage328en_US
dc.identifier.endpage339en_US
dc.institutionauthorSayıklı Şimşek, Çiğdem
dc.institutionauthorSezgintürk, Mustafa Kemal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid56029590100
dc.authorscopusid6602429563
dc.authorscopusid6506764918
dc.authorwosidSezgintürk, Mustafa Kemal/AAY-1439-2021
dc.identifier.wosWOS:000331982500014en_US
dc.identifier.scopus2-s2.0-84894355502en_US


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