Effect of left ventricular diastolic function of psoriasis

Abstract

The objective of our study was to evaluate the diastolic left heart functions of patients with no known cardiovascular disease via tissue Doppler imaging method. 50 psoriasis patients along with 30 healthy individual controls were included in the study. When the psoriasis group was compared with the control group, a decrease in left ventricular early filling time (71.8 +/-+/- 4.9 versus 81 +/-+/- 3.8, P<0.05) and increase in atrial filing [67.5 (44-93) versus 60 (46-96), P<0.05] as well as decrease in E/A ratio [1.14 (0.64-1.8) versus 1.27 (0.74-1.67), P<0.05] were observed in psoriasis patients; whereas a significant increase was not observed in the deceleration time [184 (102 - 261) versus 172 (146 - 261), P>0.05], Whereas isovolumetric relaxation time was determined to be longer [95 (55 -1 21) versus 89 (39 1 14), P<0.05] in a statistically significant manner in the psonrisis group. When the psoriasis patients were compared with the control group, septal E' [10.1 (6 - 17) versus 11 (7 - 16)] and septal E'/A' [0.9 (0.55 - 2) versus 1.42 (0.53 - 2.67)] along with lateral E' [11 (6 - 19) versus 14 (8 - 20)] and lateral E'/A' [1.09 (0.62 - 2.67) versus 1.76 (0.73 - 2.5)] were determined to be lower (P<0.05). Septal A' was determined to be higher in the psoriasis group. Our study has put forth the relationship between psoriasis and the detenriration of the functions in left ventricular diastolic functions.