dc.contributor.author | Akyüz, Aydın | |
dc.contributor.author | Aydın, Fatma | |
dc.contributor.author | Alpsoy, Şeref | |
dc.contributor.author | Özkaramanlı Gür, Demet | |
dc.contributor.author | Güzel, Savaş | |
dc.date.accessioned | 2022-05-11T14:10:12Z | |
dc.date.available | 2022-05-11T14:10:12Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 2149-2263 | |
dc.identifier.issn | 2149-2271 | |
dc.identifier.uri | https://doi.org/10.14744/AnatolJCardiol.2019.43247 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/5324 | |
dc.description.abstract | Objective: The pathophysiology of coronary slow flow (CSF) has not been clarified. Salusin-beta is released predominantly from the atheroma plaques and influences the pathophysiologic processes of atherosclerosis. Therefore, this study aimed to determine serum salusin-beta levels in CSF and its correlation with CSF. Methods: The study included 39 patients with CSF, and the control group (n=42) consisted of consecutive subjects with normal coronary arteriogram. We measured salusin-beta and thrombolysis in myocardial infarction frame count (TFC). Results: Age, body mass index (BMI), systolic blood pressure, diabetes, hyperlipidemia, and smoking rates were similar (p values>0.05) in both groups. High sensitive C-reactive protein (2.80 +/- 1.2 vs. 2.21 +/- 1.2 mg/dL, p=0.011), salusin-beta [1205 (330-2092) vs. 162 (29-676), pg/ml, p<0.001], corrected TFC of left anterior descending coronary artery (29 +/- 9 vs. 19.7 +/- 3.7, p<0.001), circumflex artery TFC (25 +/- 10 vs. 15 +/- 3.2, p<0.001), right coronary artery TFC (28 +/- 7.1 vs. 13 +/- 3.3, p<0.001), and mean TFC (28 +/- 4.4 vs. 16 +/- 3.7, p<0.001) were significantly higher in the CSF group. In univariate and multivariate regression analysis, only BMI (unstandardized beta +/- SE=0.178 +/- 0.08, p=0.036) and salusin-beta levels (unstandardized beta +/- SE=0.006 +/- 0.01, p<0.001) were determined as predictors of CSF. There was a good correlation between serum salusin-beta and mean TFC values (r=0.564; p<0.001). Conclusion: There is an association between serum salusin-beta levels and CSF. | en_US |
dc.description.sponsorship | Namik Kemal University Scientific Research Projects CommissionNamik Kemal University [02, YL.17.118] | en_US |
dc.description.sponsorship | Namik Kemal University Scientific Research Projects Commission supported this study with project number 02.YL.17.118. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Aves | en_US |
dc.identifier.doi | 10.14744/AnatolJCardiol.2019.43247 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | atherosclerosis | en_US |
dc.subject | coronary slow flow | en_US |
dc.subject | salusin-beta | en_US |
dc.subject | endothelial dysfunction | en_US |
dc.subject | Intima-Media Thickness | en_US |
dc.subject | C-Reactive Protein | en_US |
dc.subject | Nf-Kappa-B | en_US |
dc.subject | Endothelial Dysfunction | en_US |
dc.subject | Intravascular Ultrasound | en_US |
dc.subject | In-Vivo | en_US |
dc.subject | Atherosclerosis | en_US |
dc.subject | Inflammation | en_US |
dc.subject | Arteries | en_US |
dc.subject | Lesions | en_US |
dc.title | Relationship of serum salusin beta levels with coronary slow flow | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Anatolian Journal of Cardiology | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı | en_US |
dc.identifier.volume | 22 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 177 | en_US |
dc.identifier.endpage | 184 | en_US |
dc.institutionauthor | Akyüz, Aydın | |
dc.institutionauthor | Aydın, Fatma | |
dc.institutionauthor | Alpsoy, Şeref | |
dc.institutionauthor | Özkaramanlı Gür, Demet | |
dc.institutionauthor | Güzel, Savaş | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 16315021800 | |
dc.authorscopusid | 57211194682 | |
dc.authorscopusid | 6505680586 | |
dc.authorscopusid | 55317577700 | |
dc.authorscopusid | 23968920100 | |
dc.identifier.wos | WOS:000488286400007 | en_US |
dc.identifier.scopus | 2-s2.0-85072932511 | en_US |
dc.identifier.pmid | 31584433 | en_US |