dc.contributor.author | Akyüz, Aydın | |
dc.contributor.author | Akkoyun, Dursun Çayan | |
dc.contributor.author | Oran, Mustafa | |
dc.contributor.author | Değirmenci, Hasan | |
dc.contributor.author | Alp, Recep | |
dc.date.accessioned | 2022-05-11T14:10:06Z | |
dc.date.available | 2022-05-11T14:10:06Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 2090-8016 | |
dc.identifier.issn | 2090-0597 | |
dc.identifier.uri | https://doi.org/10.1155/2014/454701 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/5288 | |
dc.description.abstract | Some studies show increased mean platelet volume (MPV) in obstructive sleep apnea (OSA). The aim of this study was to evaluate MPV in OSA patients without cardiovascular risk factors and the possible association of heart rate derivatives with MPV. A total of 82 patients (aged 30-70 years) were divided into 2 groups according to the presence of either OSA or non-OSA as the control group. The OSA group consisted of 52 patients and the control group consisted of 30 subjects. Neither group was significantly different in terms of MPV values as well as heart rate (HR) derivatives such as minimum HR, maximum HR, the difference between maximum HR and minimum HR, mean HR, and heart rate performance index (HRPI) [(HR max. -HR min.)/HR mean] (P > 0.05 for all variables). In multivariate analysis, platelet count and percentages of recording time spent at arterial oxygen saturation < 90% significant variables are associated with MPV (beta +/- SE: -0.004 +/- 0.002, 95% CI, -0.008 to -0.001; P = 0.034) and (beta +/- SE: 2.93 +/- 1.93, 95% CI, 0.167 to 5.69; P = 0.038). Consequently, our findings predominantly suggest that there is a casual and reciprocal interaction between MPV and autonomic activation. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Hindawi Ltd | en_US |
dc.identifier.doi | 10.1155/2014/454701 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Positive Airway Pressure | en_US |
dc.subject | Activation | en_US |
dc.title | Mean Platelet Volume in Patients with Obstructive Sleep Apnea and Its Relationship with Simpler Heart Rate Derivatives | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Cardiology Research and Practice | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı | en_US |
dc.identifier.volume | 2014 | en_US |
dc.institutionauthor | Akyüz, Aydın | |
dc.institutionauthor | Akkoyun, Dursun Çayan | |
dc.institutionauthor | Oran, Mustafa | |
dc.institutionauthor | Değirmenci, Hasan | |
dc.institutionauthor | Alp, Recep | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.identifier.wos | WOS:000214719700015 | en_US |
dc.identifier.pmid | 25295213 | en_US |