dc.contributor.author | Abalı, Remzi | |
dc.contributor.author | Çelik, Cem | |
dc.contributor.author | Taşdemir, Nice | |
dc.contributor.author | Güzel, Savaş | |
dc.contributor.author | Alpsoy, Şeref | |
dc.contributor.author | Yüksel, Aytaç | |
dc.contributor.author | Çelik, Elçin | |
dc.date.accessioned | 2022-05-11T14:10:00Z | |
dc.date.available | 2022-05-11T14:10:00Z | |
dc.date.issued | 2013 | |
dc.identifier.issn | 0301-2115 | |
dc.identifier.uri | https://doi.org/10.1016/j.ejogrb.2013.01.023 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/5244 | |
dc.description.abstract | Objective: To investigate fetuin-A concentrations and its association with metabolic and sonographic cardiovascular markers in women with polycystic ovary syndrome (PCOS) and healthy subjects. Study design: Thirty-five women with PCOS and 37 healthy control women were matched for body mass index (BMI) and age. Serum fetuin-A concentrations, and reproductive and adrenal hormones were measured, and insulin resistance and carotid intima media thickness (CIMT) were evaluated in both groups. The correlations between cardiovascular risk factors, CIMT and fetuin-A concentrations were tested. Results: Mean fetuin-A concentrations were significantly elevated in the PCOS group compared with control subjects (101.2 ng/ml +/- 33.55 vs. 82.5 ng/ml +/- 32.65, P = 0.019). CIMT was also higher in women with PCOS than in control subjects (0.51 +/- 0.05 mm vs. 0.44 +/- 0.05 mm, P < 0.01). Serum lipid parameters were correlated to serum fetuin-A concentrations in the PCOS group, but no correlation was found between fetuin-A and CIMT (r(PCOS) = 0.244. p(PCOS) = 0.158; r(control) = 0.002, p(control) = 0.988). Conclusion: In this, the first study of fetuin-A concentrations in PCOS, the results showed that fetuin-A concentrations were increased in euglycemic patients with PCOS. (c) 2013 Elsevier Ireland Ltd. All rights reserved. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier Science Bv | en_US |
dc.identifier.doi | 10.1016/j.ejogrb.2013.01.023 | |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Polycystic ovarian syndrome | en_US |
dc.subject | Fetuin-A | en_US |
dc.subject | Carotid intima-media thickness | en_US |
dc.subject | Cardiovascular disease | en_US |
dc.subject | Insulin resistance | en_US |
dc.subject | Cardiovascular Risk-Factors | en_US |
dc.subject | Fetuin-A | en_US |
dc.subject | Endothelial Dysfunction | en_US |
dc.subject | Insulin-Resistance | en_US |
dc.subject | Young-Women | en_US |
dc.subject | Follow-Up | en_US |
dc.subject | Disease | en_US |
dc.subject | Accumulation | en_US |
dc.subject | Association | en_US |
dc.subject | Prevalence | en_US |
dc.title | The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-a concentration and carotid intima-media thickness in women with polycystic ovary syndrome | en_US |
dc.type | article | en_US |
dc.relation.ispartof | European Journal of Obstetrics & Gynecology and Reproductive Biology | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı | en_US |
dc.identifier.volume | 169 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 45 | en_US |
dc.identifier.endpage | 49 | en_US |
dc.institutionauthor | Abalı, Remzi | |
dc.institutionauthor | Çelik, Cem | |
dc.institutionauthor | Taşdemir, Nice | |
dc.institutionauthor | Güzel, Savaş | |
dc.institutionauthor | Alpsoy, Şeref | |
dc.institutionauthor | Çelik, Elçin | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 6506061779 | |
dc.authorscopusid | 24075279000 | |
dc.authorscopusid | 23986422400 | |
dc.authorscopusid | 23968920100 | |
dc.authorscopusid | 6505680586 | |
dc.authorscopusid | 55314067300 | |
dc.authorscopusid | 55597937800 | |
dc.authorwosid | Alpsoy, Seref/Z-1808-2018 | |
dc.identifier.wos | WOS:000321539300008 | en_US |
dc.identifier.scopus | 2-s2.0-84879125041 | en_US |
dc.identifier.pmid | 23433744 | en_US |