Advances in immunosensor technology
Özet
In recent years, advances in immunosensor device fabrication have significantly expanded the use of this technology in a broad range of applications including clinical diagnosis, food analysis, quality control, environmental studies and industrial monitoring. The most important aspect in fabrication is to obtain a design that provides a low detection limit. The utilization of nanomaterials as a label, catalyst and biosensing transducer is, perhaps, the most popular approach in ultrasensitive devices. This chapter reviews recent advances in immunosensor fabrication and summarizes the most recent studies. Strategies employed to significantly improve sensitivity and specificity of immunosensor technology and the advantages and limitations thereof are explored. © 2021 Elsevier Inc.
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Electrochemical Immunosensor for Detection of CCR4 Cancer Biomarker in Human Serum: An Alternative Strategy for Modification of Disposable ITO Electrode
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Wiley-VCH Verlag, 2021)Herein, a new strategy for the fabrication of a sensitive immunosensor capable of determination of CC Chemokine receptor 4 (CCR4) in complex serum samples is developed through the polymer modification on the disposable ... -
Applications of electrochemical immunosensors for early clinical diagnostics
Bahadır, Elif Burcu; Sezgintürk, Mustafa Kemal (Elsevier Science Bv, 2015)Cancer and cardiovascular diseases are the major threats to global health. Hence, there is a growing demand for a range of portable, rapid and low cost biosensing devices for the detection of these diseases. Electrochemical ... -
Highly sensitive impedimetric immunosensor for determination of interleukin 6 as a cancer biomarker by using conjugated polymer containing epoxy side groups modified disposable ITO electrode
Aydın, Elif Burcu (Elsevier B.V., 2020)A novel impedimetric immunosensor based on a conjugated polypyrrole polymer containing epoxy active side groups (PPCE) modified indium tin oxide (ITO) electrode was developed for detection of interleukin 6 (IL 6), a prostate ...