Yazar "Gacar, Nejat" için PubMed İndeksli Yayın Koleksiyonu listeleme
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Beneficial effects of resveratrol on scopolamine but not mecamylamine induced memory impairment in the passive avoidance and Morris water maze tests in rats
Gacar, Nejat; Mutlu, Oğuz; Utkan, Tijen; Çelikyurt, İpek Komşuoğlu; Göçmez, Semil Selcen; Ulak, Guner (Pergamon-Elsevier Science Ltd, 2011)Resveratrol (3,5,4-trihydroxy-trans-stilbene), which is found in grapes and red wine has been shown to protect neuronal cells with its antioxidant activity, improve memory function in dementia and reverse acetylcholine ... -
Chronic administration of fluoxetine impairs neurogenic and endothelium-dependent relaxation of the rabbit corpus cavernosum smooth muscle
Göçmez, Semil Selcen; Utkan, Tijen; Gacar, Nejat; Sarıoğlu, Yusuf (Elsevier, 2011)Antidepressants, including selective serotonin reuptake inhibitors (SSRIs), cause erectile dysfunction: however, the mechanism by which they cause erectile function is unclear. We investigated the reactivity of the corpus ... -
Chronic administration of imipramine but not agomelatine and moclobemide affects the nitrergic relaxation of rabbit corpus cavernosum smooth muscle
Göçmez, Semil Selcen; Utkan, Tijen; Gacar, Nejat (Elsevier, 2013)Sexual dysfunction is a common and underestimated effect of antidepressants. However, the mechanism by which these drugs cause erectile dysfunction is unclear. We investigated the reactivity of the corpus cavernosum of ... -
Effects of chronic low- and high-dose ethanol intake on the nitrergic relaxations of corpus cavernosum and penile nitric oxide synthase in the rabbit
Yazır, Y.; Göçmez, Semil Selcen; Utkan, Tijen; Komşuoğlu Çelikyurt, I.; Gacar, Nejat; Sarıoğlu, Y. (Nature Publishing Group, 2012)Epidemiological evidence showed that chronic ethanol consumption is a major risk factor in the development of impotence. The present study investigated the effects of carbachol-, electrical field stimulation (EFS)-, sodium ... -
Evidence for the involvement of neuronal nitric oxide synthase and soluble guanylate cyclase on cognitive functions in rats
Komsuoglu-Çelikyurt, Ipek; Göçmez, Semil Selcen; Mutlu, Oğuz; Gacar, Nejat; Arıcıoğlu, Feyza; Utkan, Tijen (Pergamon-Elsevier Science Ltd, 2011)Aims: The influence of 3-bromo-7-nitroindazole (3-Br 7-NI), a potent and selective neuronal nitric oxide synthase (nNOS) inhibitor, and [1H-[1,2,4]-oxadiazole[4,3a]-quinoxaline-1-one] (ODQ), a highly selective, irreversible ... -
Selective and nonselective neuronal NOS inhibitors impair cognitive function in the three panel runway and passive avoidance tasks in rats
Utkan, Tijen; Göçmez, Semil Selcen; Özer, Cüneyt; Gacar, Nejat; Arıcıoğlu, Feyza (Pergamon-Elsevier Science Ltd, 2012)The aim of this study was to compare the effects of both neuronal NOS (nNOS) and inducible NOS (iNOS) inhibitor 2-iminobiotin, with the more selective nNOS inhibitor N-omega-propyl-L-arginine (NPLA) and selective inducible ...