dc.contributor.author | Surov, A. | |
dc.contributor.author | Thormann, M. | |
dc.contributor.author | Kardaş, H. | |
dc.contributor.author | Hinnerichs, M. | |
dc.contributor.author | Omari, J. | |
dc.contributor.author | Cingöz, E. | |
dc.contributor.author | Cingöz, M. | |
dc.contributor.author | Chousein, O. | |
dc.contributor.author | Sasani, Hadi | |
dc.contributor.author | Gönen, Korcan Aysun | |
dc.date.accessioned | 2023-05-06T17:23:35Z | |
dc.date.available | 2023-05-06T17:23:35Z | |
dc.date.issued | 2023 | |
dc.identifier.issn | 0007-1285 | |
dc.identifier.uri | https://doi.org/10.1259/bjr.20220869 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/12169 | |
dc.description.abstract | Objective: To evaluate the association of body composition parameters with outcomes in Covid-19. Methods: 173 patients hospitalized for Covid-19 infection in 6 European centers were included in this retrospective study. Measurements were performed at L3-level and comprised skeletal muscle index (SMI), muscle density (MD), and adipose tissue measurements [visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), intramuscular adipose tissue (IMAT), visceral-to-subcutaneous-adipose-tissue-area-ratio (VSR)]. The association with mortality, the need for intubation (MV), and the need for admission to ICU within 30 days were evaluated. Results: Higher SAT density was associated with a greater risk of MV (OR = 1.071, 95%CI=(1.034;1.110), p < 0.001). Higher VAT density was associated with admission to ICU (OR = 1.068, 95%CI=(1.029;1.109), p < 0.001). Higher MD was a protective factor for MV and ICU admission (OR = 0.914, 95%CI=(0.870;0.960), p < 0.001; OR = 0.882, 95%CI=(0.832;0.934), p = 0.028). Higher VSR was associated with mortality (OR = 2.147, 95%CI=(1.022;4.512), p = 0.044). Male sex showed the strongest influence on the risk of ICU admission and MV. SMI was not associated with either parameter. Conclusion: In patients hospitalized for Covid-19 infection, higher VSR seems to be a strong prognostic factor of short-term mortality. Weak associations with clinical course were found for MD and adipose tissue measurements. Male sex was the strongest prognostic factor of adverse clinical course. Advances in knowledge: VSR is a prognostic biomarker for 30-day mortality in patients hospitalized for Covid-19 disease. © 2023 The Authors. | en_US |
dc.description.sponsorship | 01KX2021; Bundesministerium für Bildung und Forschung, BMBF | en_US |
dc.description.sponsorship | This research was supported by the German Federal Ministry of Education and Research (BMBF) as part of the University Medicine Network (Project RACOON, 01KX2021). | en_US |
dc.language.iso | eng | en_US |
dc.publisher | British Institute of Radiology | en_US |
dc.identifier.doi | 10.1259/bjr.20220869 | |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | adipose tissue | en_US |
dc.subject | adolescent | en_US |
dc.subject | adult | en_US |
dc.subject | aged | en_US |
dc.subject | anthropometric parameters | en_US |
dc.subject | Article | en_US |
dc.subject | body composition | en_US |
dc.subject | body composition parameters | en_US |
dc.subject | computer assisted tomography | en_US |
dc.subject | controlled study | en_US |
dc.subject | coronavirus disease 2019 | en_US |
dc.subject | female | en_US |
dc.subject | hospital admission | en_US |
dc.subject | hospital patient | en_US |
dc.subject | human | en_US |
dc.subject | intensive care unit | en_US |
dc.subject | intra-abdominal fat | en_US |
dc.subject | intramuscular fat | en_US |
dc.subject | intubation | en_US |
dc.subject | lumbar spine | en_US |
dc.subject | major clinical study | en_US |
dc.subject | male | en_US |
dc.subject | measurement | en_US |
dc.subject | mortality | en_US |
dc.subject | multicenter study | en_US |
dc.subject | muscle mass | en_US |
dc.subject | pandemic | en_US |
dc.subject | prediction | en_US |
dc.subject | prognosis | en_US |
dc.subject | retrospective study | en_US |
dc.subject | risk | en_US |
dc.subject | sex difference | en_US |
dc.subject | skeletal muscle | en_US |
dc.subject | subcutaneous fat | en_US |
dc.subject | visceral to subcutaneous adipose tissue ratio | en_US |
dc.subject | clinical trial | en_US |
dc.subject | diagnostic imaging | en_US |
dc.subject | disease exacerbation | en_US |
dc.subject | intra-abdominal fat | en_US |
dc.subject | subcutaneous fat | en_US |
dc.subject | Adipose Tissue | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Disease Progression | en_US |
dc.subject | Humans | en_US |
dc.subject | Intra-Abdominal Fat | en_US |
dc.subject | Male | en_US |
dc.subject | Retrospective Studies | en_US |
dc.subject | Subcutaneous Fat | en_US |
dc.title | Visceral to subcutaneous fat ratio predicts short-term mortality in patients with Covid 19. A multicenter study | en_US |
dc.type | article | en_US |
dc.relation.ispartof | British Journal of Radiology | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı | en_US |
dc.identifier.volume | 96 | en_US |
dc.identifier.issue | 1144 | en_US |
dc.institutionauthor | Chousein, O. | |
dc.institutionauthor | Sasani, Hadi | |
dc.institutionauthor | Gönen, Korcan Aysun | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 35585658600 | |
dc.authorscopusid | 57224572940 | |
dc.authorscopusid | 57416884700 | |
dc.authorscopusid | 57761613400 | |
dc.authorscopusid | 56671355500 | |
dc.authorscopusid | 57224775809 | |
dc.authorscopusid | 57190971463 | |
dc.identifier.scopus | 2-s2.0-85150751153 | en_US |
dc.identifier.pmid | 36744766 | en_US |