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Could Age and Oral Challenge Outcomes Identify High-Risk Patients During Cow's Milk Oral Immunotherapy?
Şenol, Handan Duman; Topyıldız, Ezgi; Severcan, Ezgi Ulusoy; Akercan, Sanem Eren; Günaydın, Nursen Ciğerci; Gülen, Figen; Demir, Esen (Mary Ann Liebert, Inc, 2022)Objective: Severe immunglobuline E (IgE)-mediated reactions during oral immunotherapy (OIT) are major obstacles to treatment. The present study aimed to evaluate and identify clinical and laboratory biomarkers of adverse ... -
Cut-Off Values of Specific IgE and Skin Prick Test to Predict Oral Food Challenge Positivity in Children with Cow's Milk Allergy
Günaydın, Nurşen Ciğerci; Akarcan, Sanem Eren; Gülen, Figen; Bal, Cem Murat; Tanaç, Remziye; Atasever, Mesude; Demir, Esen (Aves, 2022)Objective: The cut-off values for the skin prick test diameters and cow's milk-specific IgE measurements are used to predict the result of the oral food challenge test for the diagnosis of cow's milk allergy. This study ... -
Effects of Cow's Milk Components, Goat's Milk and Sheep's Milk Sensitivities on Clinical Findings, and Tolerance Development in Cow's Milk Allergy
Günaydın, Nurşen Ciğerci; Severcan, Ezgi Ulusoy; Akarcan, Sanem Eren; Bal, Cem Murat; Gülen, Figen; Tanac, Remziye; Demir, Esen (Kare Publ, 2021)Objective: Cow's milk (CM) contains some proteins capable of causing an allergic reaction in a sensitized individual and one of the most common causes of food allergy in childhood. Most of the patients will develop tolerance ... -
Immunologic changes during desensitization with cow's milk: How it differs from natural tolerance or nonallergic state?
Günaydın, Nursen Ciğerci; Azarsız, E.; Süslüer, S.Y.; Kütükçüler, N.; Gündüz, C.; Gülen, Figen; Demir, Esen (American College of Allergy, Asthma and Immunology, 2022)Background: Oral immunotherapy (OIT) is a novel allergen-specific treatment for food allergies. Objective: To investigate the effect of OIT on blocking antibodies, T cell regulation, and cytokine response during immunoglobulin ... -
Oral Immunotherapy for Cow's Milk Allergy: Five Years' Experience from a Single Center in Turkey
Demir, Esen; Günaydın, Nurşen Ciğerci; Gülen, Figen; Tanac, Remziye (Galenos Publ House, 2020)Background: Oral immunotherapy for cow's milk allergy is an effective treatment option because of its ability to increase the threshold for clinical reactions. Aims: To present our experience of oral immunotherapy for cow's ... -
Successful Desensitization Protocol in an Infant Following Anaphylaxis Secondary to Recombinant Factor VIIa
Ulusoy Severcan, Ezgi; Günaydın, Nurşen Ciğerci; Hekimci Özdemir, Hamiyet; Gülen, Figen; Kavaklı, Kaan; Tanaç, Remziye; Demir, Esen (Mary Ann Liebert, Inc, 2020)Background:Recombinant factor VIIa (rFVIIa) is a highly purified recombinant protein. It is approved for the treatment and prevention of bleeding episodes associated with congenital factor VII deficiency, congenital ...