dc.contributor.author | Bakır, Buket | |
dc.contributor.author | Eliş Yıldız, Sevda | |
dc.contributor.author | Karadağ Sarı, Ebru | |
dc.contributor.author | Asker, Hasan | |
dc.contributor.author | Nazli, Mumtaz | |
dc.date.accessioned | 2022-05-11T14:42:27Z | |
dc.date.available | 2022-05-11T14:42:27Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1300-6045 | |
dc.identifier.uri | https://doi.org/10.9775/kvfd.2015.14559 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/9383 | |
dc.description.abstract | The purpose of this study was to investigate the effects of capsaicin on the duodenal distribution of cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and Transforming growth factor beta-1 (TGF beta-1) in rats. Rats were divided into two groups (n = 10 in each group). Experimental group treated with capsaicin (1 mg/kg, subcutaneously) was injected in 10% ethanol, 1% Tween and 80% distilled water everyday for a period of one week and in not injected control group. Localisations of COX-1, COX-2 and TGF beta-1 were observed in villus and crypt ephitelial cells, and smooth muscle cells. In conclusion, in this study, capsaicin administration was found to increase the release of COX-1 and COX-2, and TGF beta-1. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Kafkas Univ, Veteriner Fakultesi Dergisi | en_US |
dc.identifier.doi | 10.9775/kvfd.2015.14559 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Capsaicin | en_US |
dc.subject | Cyclooxygenase | en_US |
dc.subject | Duodenum | en_US |
dc.subject | Transforming growth factor beta-1 | en_US |
dc.subject | Growth-Factor-Alpha | en_US |
dc.subject | Epithelial-Cells | en_US |
dc.subject | Factor-Beta | en_US |
dc.subject | Cyclooxygenase 2 | en_US |
dc.subject | Gene-Expression | en_US |
dc.subject | Pain Management | en_US |
dc.subject | Small-Intestine | en_US |
dc.subject | Messenger-Rna | en_US |
dc.subject | Receptor | en_US |
dc.subject | Mice | en_US |
dc.title | Immunohistochemical Distribituon of COX-1, COX-2, and TGF beta-1 in the Duodenum of Rats Treated with Capsaicin | en_US |
dc.title.alternative | Capsaicin uygulanan sıçanların duodenumda COX-1, COX-2 ve TGF?-1'in immünohistokimyasal dağılımı] | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Kafkas Universitesi Veteriner Fakultesi Dergisi | en_US |
dc.department | Fakülteler, Veteriner Fakültesi, Temel Bilimler Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-5703-2164 | |
dc.identifier.volume | 22 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 333 | en_US |
dc.identifier.endpage | 338 | en_US |
dc.institutionauthor | Bakır, Buket | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 37121662100 | |
dc.authorscopusid | 34971025700 | |
dc.authorscopusid | 27667663200 | |
dc.authorscopusid | 57188626782 | |
dc.authorscopusid | 6603667446 | |
dc.authorwosid | bakır, buket/ABA-8248-2020 | |
dc.authorwosid | Asker, Hasan/A-5543-2018 | |
dc.identifier.wos | WOS:000374312100003 | en_US |
dc.identifier.scopus | 2-s2.0-84961960524 | en_US |