dc.contributor.author | Aydın, Murat | |
dc.contributor.author | Yılmaz, Ahsen | |
dc.contributor.author | Donma, Mustafa Metin | |
dc.contributor.author | Tülübaş, Feti | |
dc.contributor.author | Demirkol, Muhammed | |
dc.contributor.author | Erdoğan, Murat | |
dc.contributor.author | Gürel, Ahmet | |
dc.date.accessioned | 2022-05-11T14:12:36Z | |
dc.date.available | 2022-05-11T14:12:36Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 2148-4902 | |
dc.identifier.uri | https://doi.org/10.14744/nci.2015.25238 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/5610 | |
dc.description.abstract | OBJECTIVE: Obesity is a growing health problem in most of the developed countries. It is associated with many chronic diseases, affecting particularly endocrine and cardiovascular systems. Inflammation plays a key role in pathophysiology of obesity. In this study, we aimed to investigate the inflammation status in obese children using neutrophil/lymphocyte ratio. METHODS: In this study 130 obese and 57 healthy children were assessed retrospectively. According to Centers for Disease Control 2000 (CDC) BMI percentiles for childhood and adulthood, 85-95 percentile was considered as overweight and >95 percentile as obese. RESULTS: Lymphocyte/neutrophil ratios in the obese group were significantly higher compared to those in healthy controls (p = 0.03 and p = 0.045, respectively). Neutrophil/lymphocyte ratio and CRP level in the obese group were significantly higher compared to those in healthy controls (p = 0.02 and p = 0.00, respectively). Thrombocyte/lymphocyte ratios were not significantly different between two groups (p = 0.156). CONCLUSION: It is possible that childhood obesity which has been increasingly prevalent recently triggers the pathogenesis of atherosclerosis during the early years of life. Increased neutrophil/lymphocyte ratio might be associated with the severity of inflammation which plays a role in the early stages of atherosclerosis. Therefore, taking childhood obesity under control using diet and other treatment methods will prevent mortality and morbidity in the elderly. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Kare Publ | en_US |
dc.identifier.doi | 10.14744/nci.2015.25238 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Childhood obesity | en_US |
dc.subject | inflammation | en_US |
dc.subject | neutrophil/lymphocyte ratio | en_US |
dc.subject | Neutrophil-Lymphocyte Ratio | en_US |
dc.subject | Mean Platelet Volume | en_US |
dc.subject | Cardiovascular-Disease | en_US |
dc.subject | Insulin-Resistance | en_US |
dc.subject | Adipose-Tissue | en_US |
dc.subject | Association | en_US |
dc.subject | Overweight | en_US |
dc.subject | Children | en_US |
dc.subject | Atherosclerosis | en_US |
dc.subject | Young | en_US |
dc.title | Neutrophil/lymphocyte ratio in obese adolescents | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Northern Clinics of Istanbul | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-4060-0583 | |
dc.authorid | 0000-0001-5992-9488 | |
dc.identifier.volume | 2 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 87 | en_US |
dc.identifier.endpage | 91 | en_US |
dc.institutionauthor | Aydın, Murat | |
dc.institutionauthor | Yılmaz, Ahsen | |
dc.institutionauthor | Donma, Mustafa Metin | |
dc.institutionauthor | Tülübaş, Feti | |
dc.institutionauthor | Demirkol, Muhammed | |
dc.institutionauthor | Erdoğan, Murat | |
dc.institutionauthor | Gürel, Ahmet | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorwosid | Donma, Mustafa Metin/ABF-2169-2021 | |
dc.authorwosid | Donma, Orkide/AAI-1853-2019 | |
dc.authorwosid | Donma, Metin/AAB-6079-2020 | |
dc.authorwosid | Yilmaz, Ahsen/ABB-1083-2021 | |
dc.identifier.wos | WOS:000439921700001 | en_US |
dc.identifier.pmid | 28058347 | en_US |