dc.contributor.author | Aydın, Elif Burcu | |
dc.contributor.author | Sezgintürk, Mustafa Kemal | |
dc.date.accessioned | 2022-05-11T14:07:25Z | |
dc.date.available | 2022-05-11T14:07:25Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 1040-0397 | |
dc.identifier.uri | https://doi.org/10.1002/elan.202060603 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/5100 | |
dc.description.abstract | A highly sensitive impedimetric immunosensor for the determination of interleukin 8 (IL 8) cancer biomarker was fabricated via simple fabrication process. A silane agent with isocyanate groups, 3-(triethoxysilyl)propyl isocyanate (IPTES), were utilized for binding of IL 8 antigen specific antibodies and self-assembled on the fluorine tin oxide (FTO) substrate with a standard silanization chemistry. Under optimum experimental conditions, the designed immunosensor had a wide linear detection range of 0.02–4 pg/mL, a low limit of detection of 11.9 fg/mL and a high sensitivity of 4.42 k? pg?1 mL cm?2. The designed biosensor displayed high reproducibility and repeatability, good selectivity against interference biomarkers. © 2021 Wiley-VCH GmbH | en_US |
dc.language.iso | eng | en_US |
dc.publisher | John Wiley and Sons Inc | en_US |
dc.identifier.doi | 10.1002/elan.202060603 | |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | 3-(triethoxysilyl)propyl isocyanate | en_US |
dc.subject | Disposable electrode | en_US |
dc.subject | Fluorine tin oxide | en_US |
dc.subject | Interleukin 8 | en_US |
dc.title | Fabrication of Electrochemical Immunosensor for Detection of Interleukin 8 Biomarker via Layer-by-layer Self-assembly Process on Cost-effective Fluorine Tin Oxide Electrode | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Electroanalysis | en_US |
dc.department | Rektörlüğe Bağlı Bölümler, Rektörlük, Bilimsel ve Teknolojik Araştırmalar Uygulama ve Araştırma Merkezi | en_US |
dc.identifier.volume | 33 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 1596 | en_US |
dc.identifier.endpage | 1605 | en_US |
dc.institutionauthor | Aydın, Elif Burcu | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 57194273220 | |
dc.authorscopusid | 6506764918 | |
dc.identifier.wos | WOS:000631854300001 | en_US |
dc.identifier.scopus | 2-s2.0-85102957235 | en_US |