dc.contributor.author | Horozo?lu, Fatih | |
dc.contributor.author | Sever, Özkan | |
dc.date.accessioned | 2022-05-11T14:35:47Z | |
dc.date.available | 2022-05-11T14:35:47Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 2146-3123 | |
dc.identifier.issn | 2146-3131 | |
dc.identifier.uri | https://doi.org/10.4274/balkanmedj.2017.1013 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/8217 | |
dc.description.abstract | Background: Intravitreal steroid injection is one of the treatment options for diabetic macular edema. Dexamethasone implant is the most novel form of intravitreal steroid therapy. Improvement in macular thickness is a well-known effect of Dexamethasone implant however, subfoveal choroidal coat thickness changes require investigation. Aims: To evaluate the early central macular thickness and subfoveal choroidal thickness alterations after single-dose dexamethasone implant injection in diabetic macular edema. Study Design: Cross-sectional study. Methods: We identified 29 patients with diabetic macular edema (29 eyes) who underwent optical coherence tomography and fundus fluorescein angiography. All patients received a single-dose intravitreal Dexamethasone implant and were followed up for central macular thickness and subfoveal choroidal thickness alterations for I hour, 1 week, 1 month, and 3 months post-injection. Results: The preoperative mean central macular thickness and subfoveal choroidal thickness measurements were 59231122.3 (412-879) gm and 264.8 +/- 53.7 (165-397) gm, respectively. Central macular thickness measurements decreased significantly in the first hour (p<0.050) and continued to decrease until the third month (p<0.001), whereas the subfoveal choroidal thickness decrement was only significant on the first day (p<0.05). Decreases in subfoveal choroidal thickness and central macular thickness of 1.5% and 5% were observed at 1 hour, however, the difference was not significant (p>0.050). The decrease in central macular thickness was significantly greater than that in subfoveal choroidal thickness at 1 day, 1 week. I month, and 3 months (p<0.001). Conclusion: Intravitreal Dexamethasone implant has a meaningful effect on central macular thickness in patients with diabetic macular edema, while subfoveal choroidal thickness decreases significantly at first day. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Galenos Publ House | en_US |
dc.identifier.doi | 10.4274/balkanmedj.2017.1013 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Choroidal coat | en_US |
dc.subject | Dexamethasone | en_US |
dc.subject | diabetes mellitus | en_US |
dc.subject | macular edema | en_US |
dc.subject | Optical Coherence Tomography | en_US |
dc.subject | Panretinal Photocoagulation | en_US |
dc.subject | Controlled-Trial | en_US |
dc.subject | Retinopathy | en_US |
dc.subject | Bevacizumab | en_US |
dc.subject | Eyes | en_US |
dc.subject | Ranibizumab | en_US |
dc.subject | Acetonide | en_US |
dc.title | Early Retinal and Choroidal Coat Thickness Changes after Intravitreal Dexamethasone Implant Injection for Diabetic Macular Edema | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Balkan Medical Journal | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalı | en_US |
dc.identifier.volume | 35 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 384 | en_US |
dc.identifier.endpage | 387 | en_US |
dc.institutionauthor | Horozo?lu, Fatih | |
dc.institutionauthor | Sever, Özkan | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 9733109900 | |
dc.authorscopusid | 50263136900 | |
dc.authorwosid | Horozoglu, Fatih/AAM-4273-2021 | |
dc.identifier.wos | WOS:000445256500006 | en_US |
dc.identifier.scopus | 2-s2.0-85054062005 | en_US |
dc.identifier.pmid | 29866639 | en_US |