dc.contributor.author | Şabudak, Temine | |
dc.contributor.author | Çalışkan, Hilmican | |
dc.contributor.author | Orak, Hakime Hülya | |
dc.contributor.author | Özer, Merve | |
dc.date.accessioned | 2022-05-11T14:15:37Z | |
dc.date.available | 2022-05-11T14:15:37Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 1478-6419 | |
dc.identifier.issn | 1478-6427 | |
dc.identifier.uri | https://doi.org/10.1080/14786419.2019.1630121 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/5994 | |
dc.description.abstract | Cirsium italicum (Savi) DC. was researched for its phytochemicals for the first time. Two new biflavonoids, 5,5'',7''-trihydroxy-3,7-dimethoxy-4'-4'''-O-biflavone (3), (8,3',4',5'-tetrahydroxy-7-O-alpha-glucosyl isoflavone)-6-8''-(4'''-hydroxy-7''-O-alpha-glucosyl isoflavone) biflavone (7), a new isoflavone, 6-2'-dihydroxy-5-methoxy isoflavonone-4'-O-alpha-D-glucopyranoside (5) and a new phenolic compound, ethyl-(2,3-dihydroxy-5,6-dimethoxy-4-acetyl) benzoate (4), together with three known compounds (1), (2) and (6) were isolated from Cirsium italicum. Their structures were elucidated by extensive 1D and 2D NMR, and MS data analyses. All compounds isolated from C. italicum exhibited antioxidant activity. However, the highest activity of the EtOAc extract is considered to be responsible for compounds (1), (2) and (3) being the main compounds. [GRAPHICS] . | en_US |
dc.description.sponsorship | TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [116Z450] | en_US |
dc.description.sponsorship | We would like to thank TUBITAK for financial support of the project (116Z450). The authors thanks to Prof. Dr. A. Orak for his assistance with the statistical evaluations. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor & Francis Ltd | en_US |
dc.identifier.doi | 10.1080/14786419.2019.1630121 | |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Cirsium italicum | en_US |
dc.subject | biflavonoids | en_US |
dc.subject | isoflavones | en_US |
dc.subject | phenolic compounds | en_US |
dc.subject | antioxidant activity | en_US |
dc.subject | Japonicum Var. Maackii | en_US |
dc.subject | Antioxidant Activity | en_US |
dc.subject | Glycosides | en_US |
dc.title | Biological activity of new flavonoids and phenolic compounds from Cirsium italicum (Savi) DC. | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Natural Product Research | en_US |
dc.department | Fakülteler, Fen Edebiyat Fakültesi, Kimya Bölümü | en_US |
dc.department | Meslek Yüksekokulları, Teknik Bilimler Meslek Yüksekokulu, Gıda İşleme Bölümü | en_US |
dc.authorid | 0000-0001-8108-5509 | |
dc.authorid | 0000-0003-4384-4265 | |
dc.authorid | 0000-0001-6356-0898 | |
dc.identifier.volume | 35 | en_US |
dc.identifier.issue | 10 | en_US |
dc.identifier.startpage | 1613 | en_US |
dc.identifier.endpage | 1619 | en_US |
dc.institutionauthor | Şabudak, Temine | |
dc.institutionauthor | Çalışkan, Hilmican | |
dc.institutionauthor | Orak, Hakime Hülya | |
dc.institutionauthor | Özer, Merve | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 6505866652 | |
dc.authorscopusid | 57196417867 | |
dc.authorscopusid | 56634751100 | |
dc.authorscopusid | 57196417785 | |
dc.authorwosid | orak, hulya/ABA-6973-2020 | |
dc.authorwosid | OZER, Merve/AAC-7839-2020 | |
dc.authorwosid | SABUDAK, Temine/AAG-6784-2019 | |
dc.identifier.wos | WOS:000473063900001 | en_US |
dc.identifier.scopus | 2-s2.0-85067857936 | en_US |
dc.identifier.pmid | 31219371 | en_US |