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Facile synthesis of the azocino[4,3-b]indole framework of strychnopivotine and other Strychnos alkaloids

dc.contributor.authorUludağ, Nesimi
dc.contributor.authorYılmaz, Recep
dc.contributor.authorAsutay, Oktay
dc.contributor.authorÇolak, Naki
dc.date.accessioned2022-05-11T14:15:33Z
dc.date.available2022-05-11T14:15:33Z
dc.date.issued2016
dc.identifier.issn0009-3122
dc.identifier.issn1573-8353
dc.identifier.urihttps://doi.org/10.1007/s10593-016-1860-4
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5950
dc.description.abstractA new synthetic route to the 1,5-methanoazocino[4,3-b]indole is described. The aim of the present study is to provide a tetracyclic skeleton for the synthesis of pentacyclic Strychnos alkaloids (tubifolidine and strychnopivotine). Starting from a carbazole derivative, the ring closure was achieved by an intramolecular aldol reaction. The final product was obtained in 45% in the overall yield over 7 steps.en_US
dc.description.sponsorshipScientific and Technical Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [112T503]en_US
dc.description.sponsorshipFinancial support provided by The Scientific and Technical Research Council of Turkey (TUBITAK) through project 112T503 is gratefully acknowledged. This research is part of Recep Yilmaz's MSc thesis.en_US
dc.language.isoengen_US
dc.publisherSpringeren_US
dc.identifier.doi10.1007/s10593-016-1860-4
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject1,5-methanoazocino[4,3-b]indoleen_US
dc.subjectStrychnos alkaloidsen_US
dc.subjectIndole Alkaloidsen_US
dc.subjectAsymmetric-Synthesisen_US
dc.subjectFormal Synthesisen_US
dc.subjectRecent Progressen_US
dc.subjectRouteen_US
dc.subjectChemistryen_US
dc.subjectUleineen_US
dc.subjectEntryen_US
dc.titleFacile synthesis of the azocino[4,3-b]indole framework of strychnopivotine and other Strychnos alkaloidsen_US
dc.typearticleen_US
dc.relation.ispartofChemistry of Heterocyclic Compoundsen_US
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümüen_US
dc.departmentMeslek Yüksekokulları, Muratlı Meslek Yüksekokulu, Kimya ve Kimyasal İşleme Teknolojileri Bölümüen_US
dc.authorid0000-0002-2819-3612
dc.identifier.volume52en_US
dc.identifier.issue3en_US
dc.identifier.startpage196en_US
dc.identifier.endpage199en_US
dc.institutionauthorUludağ, Nesimi
dc.institutionauthorYılmaz, Recep
dc.institutionauthorAsutay, Oktay
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid6507868758
dc.authorscopusid57188987797
dc.authorscopusid35080000800
dc.authorscopusid25229583900
dc.authorwosiduludag, Nesimi/AAB-1353-2020
dc.identifier.wosWOS:000376466200013en_US
dc.identifier.scopus2-s2.0-84964553611en_US


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