Dose dependent effects of Spirulina platensis on liver health in rats
Özet
Spirulina platensis which is an important microalgae is interested in both human and animal nutrition for health balance. This study's aimed to evaluate the dose dependent effects of S.platensis on body weight, height, waist circumference (WC), body mass index (BMI), waist/height ratio (WHtR), abdominal fat weight, liver weight, serum liver enzymes and liver histopathology. 30 male Wistar albino rats're used in groups; Control, SP-1(500mg/kgbw) and SP-2(1000mg/kgbw). S.platensis was administered by oral gavage daily. The body weight, height, WC, BMI, WHtR and abdominal lipid weight were calculated. Also, serum cholesterol, ALT and AST were measured. End of the study, liver tissue samples were taken and scaled and histopathologic changes were recorded. There were no differences in body conditions, but positively significant correlations were found among parameters. As the doses were considered, in groupSP-1, significant positively correlations were determined among abdominal fat, growth, height, BMI and WC statistically. Nevertheless, there were no significant changes in liver weight, serum and histopathologic analyzes. S.platensis with its high concentration of functional nutrients is called as an important alternative therapeutic food and it can be used safely. © 2020 Agricultural Research Communication Centre. All rights reserved.
Cilt
54Sayı
3Koleksiyonlar
İlgili Öğeler
Başlık, yazar, küratör ve konuya göre gösterilen ilgili öğeler.
-
Effect of hesperetin on systemic inflammation and hepatic injury after blunt chest trauma in rats
Duran, Y.; Karaboğa, İhsan (Taylor and Francis Ltd, 2020)We investigated the protective effect of hesperetin on hepatic damage after blunt chest trauma in rats using histological and biochemical methods. We used 18 adult male rats in three groups of six: control, chest trauma ... -
Investigation of hepatoprotective effect of some algae species on carbon tetrachloride-induced liver injury in rats
Altinok-Yipel, F.; Tekeli, İbrahim Özan; Özsoy, S.Y.; Güvenç, M.; Sayin, S.; Yipel, Mustafa (Taylor and Francis Ltd., 2020)The aim of this study was to investigate hepatoprotective effect of some algae species such as Spirulina platensis, Chlorella vulgaris, Laminaria japonica, Sargassum sp. on experimental acute hepatotoxicity model that ... -
The effect of silymarin on hepatic regeneration after partial hepatectomy: Is silymarin effective in hepatic regeneration?
Çetinkunar, Süleyman; Tokgöz, S.; Bilgin, Bülent Çağlar; Erdem, H.; Aktimur, R.; Can, S.; Polat, Y.; Sözen, Selim (E-Century Publishing Corporation, 2015)Aim: Silymarin from Silybum marianum was found to reduce liver injury. The aim of the present study was to investigate the effects of silymarin on hepatic regeneration in partially hepatectomized rats. Methods: Thirty ...