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A NEW REAGENT FOR EFFICIENT SYNTHESIS OF NITRILES FROM ALDOXIMES USING METHOXYMETHYL BROMIDE

dc.contributor.authorUludağ, Nesimi
dc.contributor.authorNur Giden, Özge
dc.date.accessioned2022-05-11T14:03:22Z
dc.date.available2022-05-11T14:03:22Z
dc.date.issued2019
dc.identifier.issn0035-3930
dc.identifier.urihttps://doi.org/10.33224/rrch.2019.64.11.08
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4683
dc.description.abstractThis study outlines an efficient, high-yielding, and rapid method by which to access diverse nitriles from aldoximes with methoxymethyl bromide (MOM-Br) in THF. It represents the first application of MOM-Br as a deoximation reagent to synthesize nitriles. The reaction was performed at reflux to ensure excellent yield (79-96%) of the nitriles within 20-45 minutes. Furthermore, this method has been successfully applied to the synthesis of the synthesis precursor of aromatic, heteroaromatic, cyclic, and acyclic aliphatic.en_US
dc.description.sponsorshipTekirdag Namik Kemal Universityen_US
dc.description.sponsorshipThis work was supported by Tekirdag Namik Kemal University and this research also is part of Ozge Nur Giden's MSc thesis.en_US
dc.language.isoengen_US
dc.publisherEditura Acad Romaneen_US
dc.identifier.doi10.33224/rrch.2019.64.11.08
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectaldoximeen_US
dc.subjectnitrilesen_US
dc.subjectmethoxymethyl bromideen_US
dc.subjectdehydrationen_US
dc.subjectoximesen_US
dc.subjectOne-Pot Synthesisen_US
dc.subjectMom Ethersen_US
dc.subjectDehydrationen_US
dc.subjectConversionen_US
dc.subjectAmidesen_US
dc.subjectDeprotectionen_US
dc.subjectAnticanceren_US
dc.subjectCyanationen_US
dc.subjectCatalysten_US
dc.subjectOximesen_US
dc.titleA NEW REAGENT FOR EFFICIENT SYNTHESIS OF NITRILES FROM ALDOXIMES USING METHOXYMETHYL BROMIDEen_US
dc.typearticleen_US
dc.relation.ispartofRevue Roumaine De Chimieen_US
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümüen_US
dc.identifier.volume64en_US
dc.identifier.issue11en_US
dc.identifier.startpage993en_US
dc.identifier.endpage+en_US
dc.institutionauthorUludağ, Nesimi
dc.institutionauthorNur Giden, Özge
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid6507868758
dc.authorscopusid57217182597
dc.identifier.wosWOS:000517758900008en_US
dc.identifier.scopus2-s2.0-85086645599en_US


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