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dc.contributor.authorÖztürk, İbrahim İsmet
dc.contributor.authorBanti, Christina N.
dc.contributor.authorHadjikakou, Sotiris K.
dc.contributor.authorPanagiotou, Nikos
dc.contributor.authorTasiopoulos, Anastasios J.
dc.date.accessioned2022-05-11T14:03:22Z
dc.date.available2022-05-11T14:03:22Z
dc.date.issued2019
dc.identifier.issn0020-1693
dc.identifier.urihttps://doi.org/10.1016/j.ica.2019.119094
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4681
dc.description.abstractA series of mononuclear, dinuclear and polynuclear bismuth(III) iodide complexes (1–5) bearing heterocyclic thioamide ligands, 2-mercapto-3,4,5,6-tetrahydro-pyrimidine (tHPMT), 2-mercapto-benzimidazole (MBZIM), 2-mercapto-1-methylimidazole (MMI), 2-mercaptobenzothiazole (MBZT) and 2-mercaptopyridine (PYT), have been synthesized and characterized by melting point, elemental analysis, FT-IR spectroscopy, Raman spectroscopy, 1H, 13C NMR spectroscopy, UV–Vis spectroscopy and Thermal Gravimetry-Differential Thermal Analysis (TG-DTA). Moreover, the crystal structures of 1–5 have been also determined with single crystal X-ray diffraction analysis. The use of the above mentioned heterocyclic thioamide ligands have allowed synthesis of the first examples of bismuth(III) iodide thioamide complexes. {[BiI3(tHPMT)3]} (1) is the first structural example of a neutral mononuclear bismuth(III) iodide complex with octahedral geometry around the bismuth(III) ion with meridional conformation. {[BiI2(µ2-I)(MBZIM)2]2} (2) is the first example of a dinuclear bismuth(III) iodide complex with octahedral geometry around the bismuth(III) ion with trans-S/cis-I arrangement. {[BiI(µ2-I)2(MMI)]n} (3) and {[BiI(µ2-I)2(MBZT)]n·CH3OH} (4) are the first examples of the polynuclear bismuth(III) iodide complexes with octahedral geometry around the bismuth(III) ions. The ligand molecules are coordinated via the thione sulfur atoms in both complexes but in complex 3, ligand molecules are trans to each other in polymeric chain while, in complex 4, ligand molecules are cis to each other in polymeric chain. {[BiI(µ2-S,N-PYT)2]n} (5) is the first example of a polynuclear bismuth(III) iodide complex with pentagonal bipyramidal geometry around the bismuth(III) ions. The seven coordinate bismuth(III) atom has a N2S4I-donor set consisting of one iodine atom and two chelating and bridging ?2-S,N (?2-S:?1-N) pyridine-2-thionate anions. Complexes 1–5 were evaluated for their in vitro cytotoxic activity against human adenocarcinoma cervix (HeLa) and breast (MCF-7) cancer cells. The toxicity of the complexes was studied against human fetal lung fibroblast cells (MRC-5). The influence of 1–5, upon the catalytic peroxidation of the linoleic acid by the enzyme lipoxygenase (LOX), was evaluated experimentally. © 2019 Elsevier B.V.en_US
dc.description.sponsorship114Z457; Türkiye Bilimsel ve Teknolojik Araştirma Kurumu, TÜBITAKen_US
dc.description.sponsorshipI.I.O acknowledges the financial support from The Scientific and Technological Research Council of Turkey (TUBITAK, Project No. 114Z457 ).en_US
dc.language.isoengen_US
dc.publisherElsevier S.A.en_US
dc.identifier.doi10.1016/j.ica.2019.119094
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBismuth(III) iodideen_US
dc.subjectCytotoxicityen_US
dc.subjectHeterocyclic thioamidesen_US
dc.subjectLipoxygenase inhibitionen_US
dc.subjectMain group elementsen_US
dc.subjectArchitectural acousticsen_US
dc.subjectAtomsen_US
dc.subjectCell cultureen_US
dc.subjectChelationen_US
dc.subjectComplexationen_US
dc.subjectCytotoxicityen_US
dc.subjectDifferential thermal analysisen_US
dc.subjectGeometryen_US
dc.subjectIonsen_US
dc.subjectLanthanum compoundsen_US
dc.subjectLigandsen_US
dc.subjectLinoleic aciden_US
dc.subjectMoleculesen_US
dc.subjectNuclear magnetic resonance spectroscopyen_US
dc.subjectOrganic compoundsen_US
dc.subjectPolymersen_US
dc.subjectSingle crystalsen_US
dc.subjectSpectrum analysisen_US
dc.subjectSynthesis (chemical)en_US
dc.subjectX ray powder diffractionen_US
dc.subject2-mercapto-benzimidazoleen_US
dc.subjectBismuth(III)en_US
dc.subjectHuman fetal lung fibroblasten_US
dc.subjectLipoxygenasesen_US
dc.subjectMain-group elementsen_US
dc.subjectPentagonal bipyramidal geometryen_US
dc.subjectSingle crystal X-ray diffraction analysisen_US
dc.subjectThioamidesen_US
dc.subjectBismuth compoundsen_US
dc.titleStructural architectures and biological properties of main group bismuth(III) iodide complexes with heterocyclic thioamidesen_US
dc.typearticleen_US
dc.relation.ispartofInorganica Chimica Actaen_US
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümüen_US
dc.identifier.volume497en_US
dc.institutionauthorÖztürk, İbrahim İsmet
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid36785856200
dc.authorscopusid46860923200
dc.authorscopusid6602925165
dc.authorscopusid57196276440
dc.authorscopusid6602706096
dc.identifier.wosWOS:000487820000020en_US
dc.identifier.scopus2-s2.0-85071726630en_US


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