Konu "Toxicity" için Tıp Fakültesi Koleksiyonu listeleme
Toplam kayıt 14, listelenen: 1-14
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Anti-apoptotic effects of curcumin on cadmium-induced apoptosis in rat testes
(Sage Publications Inc, 2012)Cadmium (Cd) is one of the environmental pollutants affecting various tissues and organs including testis. The aim of this study was to investigate the anti-apoptotic effects of curcumin (Cur) on Cd-induced apoptosis in ... -
Are the leading drugs against Staphylococcus aureus reallytoxic to cartilage?
(Elsevier Science London, 2016)Many studies have shown that the toxic effects of local antibiotics on bone and cartilage limit orthopedic surgeons. In this study, we evaluated three antibacterial agents used locally to treat highly mortal and morbid ... -
Beneficial effects of melatonin and BQ-123 on the rat testis damage caused by cigarette smoke
(Tubitak Scientific & Technical Research Council Turkey, 2015)Background/aim: Several studies have demonstrated that cigarette smoke has detrimental effects on testicular function. However, it is unknown whether melatonin or BQ-123 has beneficial effects on the rat testis damage ... -
Colistin nephrotoxicity increases with age
(Informa Healthcare, 2014)Background: Colistin (COL) has become the backbone of the treatment of infections due to extensively drug-resistant (XDR) Gram-negative bacteria. The most common restriction to its use is acute kidney injury (AKI). Methods: ... -
Effects of isotretinoin on serum vitamin E levels in patients with acne
(Wiley, 2013)Anecdotal reports suggest that using retinoids with vitamin E leads to improvements of some side effects due to isotretinoin. However, vitamin E blood levels have not been reported previously in patients with acne treated ... -
Effects of sodium arsenite on the some laboratory signs and therapeutic role of thymoquinone in the rats
(Verduci Publisher, 2015)OBJECTIVE: Serious health problems in humans are caused by arsenic (As) exposure, which is wide spread in the environment. Sodium arsenite (SAs), capable of inducing macromolecular damage is evaluated for its damaging ... -
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
(Spandidos Publ Ltd, 2019)The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti-pyretic and anti-spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells in vitro. After surgical ... -
Prospective comparison of the value of CARG, G8, and VES-13 toxicity tools in predicting chemotherapy-related toxicity in older Turkish patients with cancer
(Elsevier, 2022)Background: In older patients with cancer, it is very important to choose the appropriate treatment because they are at high risk for chemotherapy toxicity. Our study investigated characteristics of Cancer and Aging Research ... -
Protective effects of fish omega-3 fatty acids on doxorubicin-induced testicular apoptosis and oxidative damage in rats
(Wiley-Blackwell, 2014)The aim of this study was to examine the protective effects of fish omega-3 (n-3) fatty acids on acute doxorubicin (DOX)-induced testicular apoptosis and oxidative damage. 24 male rats were divided into three groups: ... -
Protective effects of melatonin against arsenic-induced apoptosis and oxidative stress in rat testes
(Sage Publications Inc, 2016)This study aimed to investigate the protective effects of melatonin against arsenic-induced apoptosis and oxidative stress in rat testes. A total of 27 male rats were divided into 3 groups: control (saline: 5 ml kg(-1) ... -
The protective effects of omega-3 fatty acids on doxorubicin-induced hepatotoxicity and nephrotoxicity in rats
(Sage Publications Inc, 2015)This study aims to evaluate the protective effects of omega-3 fatty acids (FAs) on doxorubicin (DOX)-induced hepatotoxicity and nephrotoxicity in rats. A total of 24 adult male Sprague Dawley rats were divided into three ... -
Protective effects of onion (Allium cepa) extract against doxorubicin-induced hepatotoxicity in rats
(Sage Publications Inc, 2016)Background/aim: Doxorubicin (DOX) is a widely used and potent chemotherapeutic agent. However, serious dose-limiting toxicity through generation of free oxygen radicals is a commonly encountered clinical problem. The aim ... -
Protective effects of thymoquinone against apoptosis and oxidative stress by arsenic in rat kidney
(Taylor & Francis Ltd, 2016)We aimed to investigate the protective role of thymoquinone (TQ) by targeting its antiapoptotic and antioxidant properties against kidney damage induced by arsenic in rats. We have used the 24 male Sprague-Dawley rats. ... -
Quercetin ameliorates methotrexate-induced renal damage, apoptosis and oxidative stress in rats
(Taylor & Francis Ltd, 2015)Background: In the present study, the protective and therapeutic effects of quercetin (QE) on renal injury induced by methotrexate (MTX) have been examined. Materials and methods: A total of 24 male rats were divided into ...