Kurum Yazarı "Bilir, Bülent" Tıp Fakültesi Koleksiyonu İçin Listeleme
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Are biological agents toxic to human chondrocytes and osteocytes?
İşyar, Mehmet; Bilir, Bülent; Yılmaz, İbrahim; Çakmak, Selami; Şirin, Duygu Yaşar; Yıldırım Güzelant, Aliye; Mahiroğulları, Mahir (Bmc, 2015)Purpose: The aim of the present study is to investigate the effects of biological agents (BAs) on human chondrocytes and osteocytes in vitro. Methods: Primary cell cultures obtained from gonarthrosis patients were divided ... -
Are the leading drugs against Staphylococcus aureus reallytoxic to cartilage?
Doğan, Mustafa; İşyar, Mehmet; Yılmaz, İbrahim; Bilir, Bülent; Şirin, Duygu Yaşar; Çakmak, Selami; Mahiroğulları, Mahir (Elsevier Science London, 2016)Many studies have shown that the toxic effects of local antibiotics on bone and cartilage limit orthopedic surgeons. In this study, we evaluated three antibacterial agents used locally to treat highly mortal and morbid ... -
Are treatment guides and rational drug use policies adequately exploited in combating respiratory system diseases?
Doğan, Mustafa; Mutiu, Levent C.; Yılmaz, İbrahim; Bilir, Bülent; Saraçoğlu Varol, Gamze; Yıldırım Güzelant, Aliye (Elsevier Science London, 2016)The aim of the present study was to increase awareness regarding the rational use of medicines. The data were obtained via the Material Resources Management System Module of the Ministry of Health. For the appropriateness ... -
Association of apelin, endoglin and endocan with diabetic peripheral neuropathy in type 2 diabetic patients
Bilir, Bülent; Bilir, Betül Ekiz; Yılmaz, I.; Atile, N. Soysal; Yıldırım, Tülay; Kara, Sonat Pınar; Aydın, M. (Verduci Publisher, 2016)OBJECTIVE: Diabetic peripheral neuropathy is a common complication of type-2 diabetes mellitus. Endocan, apelin and endoglin are thought to be associated with endothelial dysfunction, angiogenesis and inflammation. In this ... -
Association of coronary artery disease severity and disulphide/native thiol ratio
Bilir, Bülent; Akkoyun, Dursun Çayan; Aydın, Murat; Özkaramanlı Gür, Demet; Değirmenci, Hasan; Albayrak, Neslihan; Erel, Özcan (Modestum Ltd, 2017)Objective: Oxidative stress is among the major components of cardiovascular disease pathogenesis. Thiols play a significant role in prevention of oxidative stress in the cell. The purpose of this study is to investigate ... -
Association of coronary artery disease severity and disulphide/native thiol ratio (vol 14, pg 30, 2017)
Bilir, Bülent; Akkoyun, Dursun Çayan; Aydın, Murat; Özkaramanlı Gür, Demet; Kara, Sonat Pınar; Değirmenci, Hasan; Erel, Özcan (Modestum Ltd, 2018)[No Abstract Available] -
The association of vitamin D with inflammatory cytokines in diabetic peripheral neuropathy
Bilir, Bülent; Tülübaş, Feti; Bilir, Betül Ekiz; Atile, N.S.; Kara, Sonat Pınar; Yıldırım, Tülay; Aydın, M. (Society of Physical Therapy Science (Rigaku Ryoho Kagakugakkai), 2016)[Purpose] The effects of vitamin D on the circulating levels of IL-17 and IL-13 were investigated in patients with diabetic peripheral neuropathy, patients with diabetes mellitus type 2 without neuropathy, and healthy ... -
Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with COPD
Aydın, Murat; Altıntaş, Nejat; Mutlu, Levent Cem; Bilir, Bülent; Oran, Mustafa; Tülübaş, Feti; Gürel, Ahmet (Wiley, 2017)IntroductionAsymmetric dimethylarginine (ADMA) and nitric oxide (NO) show their mechanism of action reciprocally, the balance between these molecules contributes to the tight regulation of airways tone and function. ... -
Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with COPD (Meeting Abstract)
Aydın, Murat; Altıntaş, Nejat; Mutlu, Levent Cem; Bilir, Bülent; Oran, Mustafa; Tukubas, Feti; Topçu, Birol (European Respiratory Soc Journals Ltd, 2015)[No Abstract Available] -
Author's reply
Akkoyun, Dursun Çayan; Akyüz, Aydın; Kurt, Ömer; Bilir, Bülent; Alpsoy, Şeref; Güler, Niyazi (Turkish Society of Cardiology, 2016)[No abstract available] -
Effect of CPAP on New Endothelial Dysfunction Marker, Endocan, in People With Obstructive Sleep Apnea
Altıntaş, Nejat; Mutlu, Levent Cem; Akkoyun, Dursun Çayan; Aydın, Murat; Bilir, Bülent; Yılmaz, Ahsen; Malhotra, Atul (Sage Publications Inc, 2016)Obstructive sleep apnea (OSA) is associated with increased cardiovascular (CV) morbidity and mortality. Endocan is a surrogate endothelial dysfunction marker that may be associated with CV risk factors. In this study, we ... -
The effect of ezetimibe monotheraphy on mean platelet volume in patients with hyperlipidaemia: a retrospective study of 45 patients
Sertbaş, Yaşar; Sertbaş, Meltem; Ersoy, Uğur; Bilir, Bülent; Günaydın, Seracettin; Özdemir, Ali (Pakistan Medical Assoc, 2016)Objective: To investigate the effect of ezetimibe on platelet functions as a drug which increases mevalonate levels. Methods: This retrospective study was conducted in Istanbul, Turkey, and comprised record of normolipidaemic ... -
The effect of ezetimibe monotherapy on lipoprotein-(a) and other lipid parameters
Bilir, Bülent; Ekiz Bilir, Betül; Takir, M.; Sertbaş, Y.; Akıncı, C.M.; Çiftçi, H. (Logos Medical Publishing, 2015)The effect of ezetimibe monothrepy on decreasing lipid molecules has been widely studied in the literature so far, but scarce number of clinical studies have evaluated the effect of this pharmacological agent on lipoprotein-(a). ... -
The effects of melatonin on liver functions in arsenic-induced liver damage
Bali, İlhan; Bilir, Bülent; Emir, Seyfi; Turan, Filiz; Yılmaz, Ahsen; Gökkuş, Tuba; Aydın, Murat (Turkish Surgical Assoc, 2016)Objective: Arsenic exposure is increasing in communities due to environmental pollution and industrial development. Arsenic is toxic to organ systems because it causes oxidative stress, enzymatic inhibition, and damage to ... -
Evaluation of Calciferol, Cobalamin, and Stromelysin-1 in Patients with Diabetic Peripheral Neuropathy due to Type-2 Diabetes Mellitus
Bilir, Bülent; Yılmaz, İbrahim; Karaarslan, Numan; Bilir, B.E.; Kaplan, Nuray; Özbek, Hanefi (College of Physicians and Surgeons Pakistan, 2022)Objective: To evaluate the relationship between calciferol (vitamin D), cobalamin (vitamin-B12), and Stromelysin-1 (MMP-3) circulating levels in patients with diabetic peripheral neuropathy (DPN), patients with DM type 2 ... -
Evaluation of endocan and endoglin levels in chronic kidney disease due to diabetes mellitus
Ekiz Bilir, Betül; Bilir, Bülent; Aydın, Murat; Soysal Atile, Neslihan (Termedia Publishing House Ltd, 2019)Introduction: Endocan and endoglin have been shown to play a role in angiogenesis. Aberrant excessive angiogenesis is a main factor in the development of diabetic nephropathy. In this study we evaluated endocan and endoglin ... -
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in septic arthritis
Bilir, Bülent; İşyar, Mehmet; Yılmaz, İbrahim; Saraçoğlu Varol, Gamze; Çakmak, Selami; Doğan, Mustafa; Mahiroğulları, Mahir (Sage Publications Inc, 2015)Is neutrophil-to-lymphocyte ratio high in patients with septic arthritis? Septic arthritis may lead to higher rates of morbidity or even mortality if not diagnosed on time. This study was planned to answer the question ... -
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in spondylodiscitis
Karaarslan, Numan; Yılmaz, İbrahim; Akgün, Feride Sinem; Çalışkan, Tezcan; Doğan, Mustafa; Bilir, Bülent; Ateş, Özkan (2018)Aim: Spondylodiscitis, if not diagnosed on time, can cause morbidity or mortality at high rates. This study was carried out with the aim of testing the hypothesis that “neutrophil-to-lymphocyte ratio can be used” especially ... -
Evaluation of red cell distribution width (RDW) in diabetic nephropathy patients
Bilir, Bülent; Ekiz Bilir, Betül; Soysal Atile, N.; Takır, M.; Yılmaz, A.; Aydın, M. (Logos Medical Publishing, 2016)Diabetic nephropathy (DN) is an important cause of morbidity and mortality of diabetes mellitus (DM) patients. Inflammation has a pivotal role in DN pathogenesis. Red cell distribution width (RDW) is a current parameter ... -
Evaluation of SCUBE-1 and sCD40L biomarkers in patients with hypothyroidism due to Hashimoto's thyroiditis: a single-blind, controlled clinical study
Bilir, Bülent; Soysal Atile, Neslihan; Bilir, Betül Ekiz; Yılmaz, I.; Bali, İlhan; Altıntaş, Nejat; Güldiken, Sibel; Aydın, M. (Verduci Publisher, 2016)OBJECTIVE: This study was performed to investigate the levels of platelet activation marker SCUBE-1 and sCD40L which plays some role in the progression of atherosclerosis, in patients with hypothyroidism due to Hashimoto's ...