Yazar "Uzun, Hafize" için Tıp Fakültesi Koleksiyonu listeleme
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The association of lectin-like oxidized LDL receptor 1 (LOX-1) K167N and 3'UTR188CT polymorphisms with maternal plasma soluble LOX-1 levels and preeclampsia risk in Turkish population
Tüten, Abdullah; Aydemir, Birsen; Öncül, Mahmut; Kızıler, Ali Rıza; Açıkgöz, A.Serdar; Güntaş Korkmaz, Gülcan; Uzun, Hafize (Springer Heidelberg, 2015)To investigate the main effect of polymorphisms in genes involved in endothelial pathophysiological mechanisms, LOX-1 K167N and 3'UTR188CT single nucleotide polymorphisms (SNPs) in relation to preeclampsia (PE) risk and ... -
The effects of hyperbaric oxygen application against cholestatic oxidative stress and hepatic damage after bile duct ligation in rats
Ayvaz, Süleyman; Kanter, Mehmet; Aksu, Burhan; Şahin, Sevtap Hekimoglu; Uzun, Hafize; Erboğa, Mustafa; Pul, Mehmet (Academic Press Inc Elsevier Science, 2013)Background: The aim of this study was to evaluate the preventive and therapeutic potential of hyperbaric oxygen therapy (HBO) on the liver tissue against bile duct ligation (BDL)-induced oxidative damage and fibrosis in ... -
Evaluation of the relationship between serum ghrelin levels and cancer cachexia in patients with locally advanced nonsmall-cell lung cancer treated with chemoradiotherapy
Uysal, Pelin; Usul Afşar, Çiğdem; Sözer, Volkan; İnanç, Berrin; Ağaoğlu, Fulya; Güral, Zeynep; Uzun, Hafize; Fazlıoğlu, Nevin (Wolters Kluwer Medknow Publications, 2020)Background: Ghrelin plays a role in mechanisms related to cancer progression - including cell proliferation, invasion and migration, and resistance to apoptosis in the cell lines from several cancers. We investigated the ... -
LOX-1 gene variants and maternal levels of plasma oxidized LDL and malondialdehyde in patients with gestational diabetes mellitus
Aydemir, Birsen; Baykara, Onur; Cinemre, Fatma Behice Serinkan; Cinemre, Hakan; Tüten, Abdullah; Kızıler, Ali Rıza; Uzun, Hafize (Springer Heidelberg, 2016)Purpose The aim of this study was to investigate the relationships between the maternal levels of oxidized LDL (ox-LDL), lipid peroxidation marker malondialdehyde (MDA) and LOX-1 3'UTR188C/T and K167N single nucleotide ... -
Paraoxonase and Arylesterase Activities, Lipid Profile, and Oxidative Damage in Experimental Ischemic Colitis Model
Ünal, Ethem; Eriş, Cengiz; Kaya, Bülent; Uzun, Hafize; Çavdar, Faruk; Yıldar, Murat; Titiz, Mesut İzzet; Kızıler, Ali Riza (Hindawi Ltd, 2012)Objective. In the present study, since PON1 is known as an HDL-associated antioxidant enzyme that inhibits the oxidative modification of LDL and oxidative stress plays a role in the pathogenesis of mesenteric ischemia, we ... -
Serum paraoxonase (a high-density lipoprotein-associated lipophilic antioxidant) activity in clinical follow-up of patients with acute pancreatitis, with particular emphasis on oxidative stress parameters and lipid profile: a prospective pilot trial
Yüksekdağ, Sema; Yüksel, Esra; Topçu, Ahmet; Karaağaç, Neslihan; Uzun, Hafize; Kızıler, Ali Rıza; Ünal, Ethem (Taylor & Francis Ltd, 2019)The purpose of this study was to investigate the possible role of PON-1, an antioxidant lipophilic enzyme linked to HDL-C (high-density lipoprotein cholesterol), on the pathophysiology and clinical follow-up of acute ...