Konu "major clinical study" için Tıp Fakültesi Koleksiyonu listeleme
Toplam kayıt 84, listelenen: 41-60
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Evaluation of the relationship between serum ghrelin levels and cancer cachexia in patients with locally advanced nonsmall-cell lung cancer treated with chemoradiotherapy
(Wolters Kluwer Medknow Publications, 2020)Background: Ghrelin plays a role in mechanisms related to cancer progression - including cell proliferation, invasion and migration, and resistance to apoptosis in the cell lines from several cancers. We investigated the ... -
Firmicutes/Bacteroidetes Ratio in the Gut Microbiota and IL-1?, IL-6, IL-8, TLR2, TLR4, TLR5 Gene Expressions in Type 2 Diabetes
(Verlag Klinisches Labor GmbH, 2022)Background: The aim of this study was to determine the Firmicutes/Bacteroidetes ratio in the gut microbiota and IL-1?, IL-6, IL-8, TLR2, TLR4 and TLR5 gene expression levels in the blood of adult type 2 diabetes (T2D) ... -
Gas6 expression and tyrosine kinase axl sky receptors: Their relation with tumor stage and grade in patients with bladder cancer
(Page Press Publications, 2021)Objectives: It has been shown that the dysregulation of tyrosine kinase Axl receptor and its ligand growth arrest-specific gene (Gas6) are associated with poor prognosis in various types of tumors but there is not enough ... -
Histopathological and molecular findings in 98 cases of endometrial carcinoma: MMR, p53 and next generation sequencing
(Elsevier GmbH, 2023)Gynecological malignancies arise from hereditary and somatic mutations, transcriptional aberrations, and genomic alterations influenced by epigenetic factors. This study aims to identify the mutations and their frequency ... -
Immunogenicity after CoronaVac vaccination
(Associacao Medica Brasileira, 2021)OBJECTIVE: This study aimed to investigate the seropositivity of CoronaVac-SinoVac vaccination in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) risk factors and comorbidities. METHODS: Immunoglobulin (IgG) ... -
The importance of examining antinuclear antibody (ANA) in neurological diseases
(2013)Objective: In neurological clinical practice screening test for ANA (Anti-nuclear antibody) is helpful in the diagnosis of autoimmune diseases which have neurological involvement. ANA investigation tests might be positive ... -
Incidence, etiology, and antibiotic resistance patterns of Gram-negative microorganisms isolated from patients with ventilator-associated pneumonia in a medical-surgical intensive care unit of a teaching hospital in Istanbul, Turkey (2004-2006)
(2008)The identification of microorganisms causing ventilator-associated pneumonia (VAP) is important for formulating appropriate therapies. In this study, we report the incidence, etiology, and antibiotic resistance patterns ... -
Increased childhood abuse in patients with premenstrual dysphoric disorder in a Turkish sample: A cross-sectional study
(Physicians Postgraduate Press Inc., 2014)Objective: Abuse is considered to have a place in the etiology of various psychiatric disorders. Premenstrual dysphoric disorder (PMDD) is one of the psychiatric disorders for which abuse could be an etiologic factor; ... -
infection and vaccination status of children aged 6 months-12 years: Time for mass vaccination
(Kowsar Medical Publishing Company, 2013)Objective: This study was designed to determine the current age-related hepatitis A virus (HAV) seroprevalance, vaccination status of children and to evaluate the epidemiological shift in HAV serostatus living in Tekirda?, ... -
Investigation of the peripheral inflammation (neutrophil-lymphocyte ratio) in two neurodegenerative diseases of the central nervous system
(Springer-Verlag Italia s.r.l., 2022)Introduction: Alzheimer’s disease (AD), and idiopathic Parkinson’s disease (IPD) are the neurodegenerative diseases of the central nervous system (CNS). Cognitive impairment is on the forefront in AD. However, IPD is a ... -
Investigation of the serum brain-derived neurotrophic factor in patients with alopecia areata: A preliminary study
(Istanbul Universitesi, 2014)Objectives: Alopecia areata (AA) is an asymptomatic hair loss; with mostly single, well-defined patches and in-group of non-scarring alopecia. There have been numerous studies that reported high percentages of psychiatric ... -
Is 99mTc-MDP whole body bone scintigraphy adjuvant to 18F-FDG-PET for the detection of skeletal metastases?
(Journal of B.U.ON., 2014)Purpose: Due to the fact that fiuorine-18-fiuorodeoxyglucose positron emission tomography/computed tomography CSF-FDG-PET/CT) and technetium-99m- methylenediphosphonate (99mTc-MDP) whole body scans identify bone metastases ... -
Is there any link between atrial arrhythmias and inflammatory bowel disease?
(Wolters Kluwer Medknow Publications, 2021)Background: Inflammation plays an important role in the development of cardiovascular disease, including atherosclerosis and arrhythmia. The aim of this study was to evaluate atrial conduction times (ACTs) in patients with ... -
İrritabl Barsak Sendromlu Hastalarda Patolojik Endişe ve Üst-bilişsel İnançların İncelenmesi
(Istanbul Universitesi, 2016)ÖZET Amaç: İrritabl Barsak Sendromu toplumun yaklaşık %20’sini etkileyen fonksiyonel bir gastrointestinal hastalıktır. İrritabl Barsak Sendromu psikiyatrik belirtilerle yakından ilişkilidir. Bu çalışmada İrritabl Barsak ... -
A morphometric evaluation of anterior fontanel and cranial sutures in infants using computed tomography
(Ondokuz Mayis Universitesi, 2022)To retrospectively analyze anterior fontanel (AF) and the morphometric findings of cranial sutures in infants under two years of age who underwent cranial computed tomography (CT). A total of 227 cases, who had cranial CT ... -
Most proper timing of transcutaneous bilirubin measurement after phototherapy treatment in the newborn period
(Kowsar Medical Institute, 2021)Background: There are limited data about the proper transcutaneous bilirubin measuring time to detect levels that are close to serum bilirubin levels after ending the phototherapy treatment. Objectives: To compare the ... -
A new center: First six months analysis of adult cardiac surgery
(2012)Objective: Cardiac surgery centers are developing and growing in recent years. We aimed to evaluate the first six months results of cardiac surgery operations that performed in our clinic which built new. Material and ... -
A new method for diagnosis of anterior cruciate ligament tear: MRI with maximum flexion of knee in the prone position: A case control study
(Elsevier Ltd, 2019)Background: The diagnosis of anterior cruciate ligament tear can be made by physical examination and magnetic resonance imaging (MRI) in the supine position. In cases where the tear is partially evaluated on MRI, the choice ... -
Next generation sequencing analysis of BRCA1 and BRCA2 identifies novel variations in breast cancer
(Elsevier Inc., 2020)Mutations in two major breast cancer susceptibility genes, BRCA1 and BRCA2, have been identified to be the most important predisposing factors for the development of breast cancer. Thus, BRCA1/2 testing is a well-established ... -
Next-generation screening of a panel of genes associated with periodic fever syndromes in patients with Familial Mediterranean Fever and their clinical characteristics
(Academic Press Inc., 2020)Familial Mediterranean Fever (FMF) is a hereditary fever syndrome that primarily affects Mediterranean populations. For the study, total number of 182 patients with FMF disease were enrolled and screening of a panel of ...