Konu "Oxidative Stress" için Tıp Fakültesi Koleksiyonu listeleme
Toplam kayıt 48, listelenen: 21-40
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Evaluation of metallothionein-1, metallothionein-2, lipid peroxidation and trace elements status in the progression of the spontaneous mitral chordae tendineae rupture patients
(Dustri-Verlag Dr Karl Feistle, 2016)Objective: The aim of the present study was to investigate whether copper, zinc and iron levels and copper/zinc, iron/zinc, iron/copper ratios in serum and erythrocytes are associated with lipid oxidation levels, ... -
The Evaluation of the Relationship between Bladder Cancer and Oxidative Stress Using NRF-2/KEAP-1 Pathway, Zinc and Copper Levels
(Urology and Nephrology Research Centre, 2021)Purpose: It has been shown that Copper and Zinc contribute to the structure of the antioxidant enzymes. In addition, NRF-2 and KEAP-1 complex have a powerful effect on the intracellular organization of the antioxidants. ... -
Gastroprotective effect of apricot kernel oil in ethanol-induced gastric mucosal injury in rats
(Taylor & Francis Ltd, 2018)We investigated the gastroprotective effect of apricot kernel oil on ethanol induced gastric ulcer in rats. Male Wistar albino rats were divided into control, ethanol and apricot kernel oil + ethanol groups. The fatty acid ... -
Hyperbaric oxygen treatment ameliorates lung injury in paraquat intoxicated rats
(E-Century Publishing Corp, 2015)Paraquat (PQ) is an agrochemical agent commonly used worldwide, which can cause acute lung injury (ALI) and death. Hyperbaric oxygen treatment (HBOT) is a therapeutic method, but the mechanisms of the protective effect of ... -
In Vitro Fertilization, Levels of Pro-Inflammatory Factors and Lipid Peroxidation
(Royan Inst, 2015)Background: Infertility is a problem concerning 10-15% of the individuals in the fertile period. This study investigated effects of proinflammatory factors as well as lipid hydroperoxides (LPO) levels upon in vitro ... -
Increased serum levels of apoptosis in deficit syndrome schizophrenia patients: a preliminary study
(Dove Medical Press Ltd, 2016)Background: Schizophrenia is a chronic and debilitating disorder, the etiology of which remains unclear. Apoptosis is a programmed cell death mechanism that might be implicated in neuropsychiatric disorders, including ... -
Is meteorin-like (Metrnl) a novel biomarker to distinguish patients with obstructive sleep apnea (OSA) and patients with OSA at vascular risk
(Springer Heidelberg, 2023)PurposeMetrnl, a newly discovered adipokine with significant expression in white adipose tissue, promotes energy expenditure and contributes to the development of cardiovascular disorders. Endocan is a surrogate marker for ... -
Kronik Obstrüktif Akciğer Hastalığı Olan Hastalarda Kognitif Fonksiyonların Değerlendirilmesi
(Yerkure Tanitim & Yayincilik Hizmetleri A S, 2018)Objective: Chronic obstructive pulmonary disease (COPD) is characterized with air flow limitation. Cognitive problems can appear in advanced stage of COPD. There is relationship between COPD and levels of homocystein (hcy) ... -
May the level and ratio changes of trace elements be utilized in identification of disease progression and grade in prostatic cancer?
(Dustri-Verlag Dr Karl Feistle, 2010)Objective: The effects of the level and ratio changes in the trace elements have been reported previously in several diseases. The aim of this study was to determine whether those trace elements (Cu, Fe and Zn) can be used ... -
Protective effect of 5-HT7 receptor activation against glutamate-induced neurotoxicity in human neuroblastoma SH-SY5Y cells via antioxidative and antiapoptotic pathways
(Pergamon-Elsevier Science Ltd, 2019)Serotonin exerts anti-inflammatory, antioxidant and antiapoptotic effects through 5-HT7 receptors. The present study determined the role of 5-HT7 receptors in glutamate-induced neurotoxicity by using human SH-SY5Y neuroblastoma ... -
Protective Effect of Alpha Lipoic Acid on Rat Sciatic Nerve Ischemia Reperfusion Damage
(Galenos Publ House, 2015)Background: Alpha lipoic acid is a potent antioxidant that plays numerous roles in human health. This study examined the effect of ALA on rat sciatic nerve ischemia reperfusion damage. Aims: Protective effect of alpha ... -
Protective Effect of Nigella Sativa on Renal Reperfusion Injury in Rat
(Iranian Soc Nephrolgy, 2016)Introduction. This study was designed to investigate the effect of Nigella sativa (NS), in reperfusion-induced renal injury in rats. Materials and Methods. A total of 24 male Sprague-Dawley rats were divided into 3 groups ... -
Protective Effects of Curcumin against Formaldehyde-Induced Renal Toxicity in Rats
(Univ West Indies Faculty Medical Sciences, 2021)Objective: To explore the protective effects of curcumin against renal injury induced by formaldehyde in rats. Methods: A total of 21 male Sprague-Dawley rats were included. The animals were divided into three groups. The ... -
The protective effects of endothelin-A receptor antagonist BQ-123 in pentylenetetrazole-induced seizure in rats
(Sage Publications Ltd, 2014)Endothelin-1 has been shown to increase neuronal activity and glutaminergic synaptic transmission by endothelin-A receptors (ETAR) in the nucleus tractus solitarius neurons that play an important role in epileptic seizures. ... -
Protective effects of irbesartan and alpha lipoic acid in STZ-induced diabetic nephropathy in rats
(Taylor & Francis Ltd, 2010)The aim of this study was designed to investigate the possible beneficial effects of the angiotensin (ang) II T-1 (AT(1)) receptor blocker, irbesartan (Irb), and the alpha lipoic acid (ALA) in streptozotocin (STZ)-induced ... -
Protective effects of melatonin against formaldehyde-induced oxidative damage and apoptosis in rat testes: An immunohistochemical and biochemical study
(2008)This study investigated the protective effects of melatonin against formaldehyde-induced oxidative damage and apoptosis in rat testes. A total of 21 male Wistar rats were divided into three groups. Group I was used as a ... -
Protective effects of Urtica dioica L. on experimental testicular ischaemia reperfusion injury in rats
(Wiley, 2017)In this study, it was aimed to examine the effects of Urtica dioica L. (UD) that has antioxidant feature in the experimental testicular I/R model in rats in terms of anti-apoptotic and antioxidative effects. In our study, ... -
Purine Catabolic Enzymes and Nitric Oxide in Patients with Iron Deficiency Anemia
(Carbone Editore, 2014)Introduction: To clarify the mechanism of oxidative damage,which affects many tissues and organ systems in iron deficiency anemia, comes into prominence in the treatment and avoiding the complications of the disease. In ... -
Quercetin Inhibits Heart Injury in Lipopolysaccharide-induced Endotoxemic Model by Suppressing the Effects of Reactive Oxygen Species
(Sci Printers & Publ Inc, 2016)OBJECTIVE: To examine the histopathological and biochemical effects of quercetin (QE), which has antioxidant properties, on damaged heart muscle in a lipopolysaccharide (LPS)-induced endotoxemia model in rats. STUDY DESIGN: ... -
The role of NMDA glutamate receptors in lung injury caused by chronic long-term intermittent hypobaric hypoxia
(Assoc Bras Divulg Cientifica, 2023)Chronic intermittent hypoxia (CIH), a component of sleep apnea-hypopnea syndrome, is suggested to cause damage to lung tissue, and the role of glutamate is not well studied. We used a chronic long-term intermittent hypobaric ...