Bölüm "Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyoloji Ana Bilim Dalı" Tıp Fakültesi Koleksiyonu için listeleme
Toplam kayıt 28, listelenen: 21-28
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Next-generation screening of a panel of genes associated with periodic fever syndromes in patients with Familial Mediterranean Fever and their clinical characteristics
(Academic Press Inc., 2020)Familial Mediterranean Fever (FMF) is a hereditary fever syndrome that primarily affects Mediterranean populations. For the study, total number of 182 patients with FMF disease were enrolled and screening of a panel of ... -
Novel thiosemicarbazone derivative 17B interferes with the cell cycle progression and induce apoptosis through modulating downstream signaling pathways
(Elsevier, 2020)Thiosemicarbazones (TSCs) are interesting group of chemical compounds that received significant levels of attention due their wide range of pharmacological effects including antibacterial, antiviral, and especially anti-tumor ... -
Prostat Kanseri Moleküler Mekanizmasında Kodlanmayan Rna'ların Rolü
(2019)Kodlanmayan RNA’lar (ncRNA), bir açık okuma çerçevesibulunmayan ve proteine çevrilemeyen işlevsel RNAtranskriptleridir. NcRNA’lar transkripsiyon ve transkripsiyonsonrası işlemlerde düzenleyici rollere ve halenaçıklanmaya ... -
The role of TMPRSS6 gene variants in iron-related hematological parameters in Turkish patients with iron deficiency anemia
(Elsevier Science Bv, 2018)TMPRSS6 gene mutations can result in iron deficiency anemia (IDA) and cause an increased iron-regulatory hormone, hepcidin, levels. TMPRSS6 encodes a serine protease, matriptase-2, which functions as negative regulatory ... -
Silencing of TP73-AS1 impairs prostate cancer cell proliferation and induces apoptosis via regulation of TP73
(Springer Science and Business Media B.V., 2022)Background: Prostate cancer is a malignant disease that severely affects the health and comfort of the male population. The long non-coding RNA TP73-AS1 has been shown to be involved in the malignant transformation of ... -
Ultrasound processing of verjuice (unripe grape juice) vinegar: effect on bioactive compounds, sensory properties, microbiological quality and anticarcinogenic activity
(Springer, 2020)Verjuice is one of the alternative fruit juices recently obtained from unripe grapes. In this study, the aim was primarily to optimize the process conditions for the enrichment of bioactive components in verjuice vinegar ... -
Urothelial bladder cancer immunotherapy strategies
(Nova Science Publishers, Inc., 2020)Bladder cancer is a highly heterogeneous malignant disease and is associated with various molecular characteristics and distinctive clinical outcomes. Bladder cancer is one of the most important health problems due to its ... -
Wwox Gen İfadesinin Kronik Lenfositik Lösemi İle İlişkisi
(2020)Amaç: WW alanı içeren oksidoredüktaz (WWOX) geni kromozom 16q23.3-q24.1 bölgesinde bulunmaktadır ve yaygın kromozomal frajilbölge, FRA16D, içermektedir. WWOX geni 46 kDa moleküler ağırlığında WWOX tümör baskılayıcı proteini ...