Bölüm "Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Tıbbi Farmakoloji Ana Bilim Dalı" Tıp Fakültesi Koleksiyonu için listeleme
Toplam kayıt 52, listelenen: 1-20
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Agmatine, a metabolite of L-arginine, reverses scopolamine-induced learning and memory impairment in rats
(Pergamon-Elsevier Science Ltd, 2012)Agmatine (1-amino-4-guanidino-butane), a metabolite of L-arginine through the action of arginine decarboxylase, is a novel neurotransmitter. In the present study, effects of agmatine on cognitive functions have been evaluated ... -
Anti-inflammatory and ultrastructural effects of Turkish propolis in a rat model of endotoxin-induced uveitis
(Via Medica, 2016)Introduction. Experimental animal models of acute uveitis, an inflammatory eye disease, can be established via endotoxin-induced inflammation. Propolis, a natural substance collected by honeybees from buds and tree exudates, ... -
Beneficial effects of resveratrol on scopolamine but not mecamylamine induced memory impairment in the passive avoidance and Morris water maze tests in rats
(Pergamon-Elsevier Science Ltd, 2011)Resveratrol (3,5,4-trihydroxy-trans-stilbene), which is found in grapes and red wine has been shown to protect neuronal cells with its antioxidant activity, improve memory function in dementia and reverse acetylcholine ... -
Chronic administration of fluoxetine impairs neurogenic and endothelium-dependent relaxation of the rabbit corpus cavernosum smooth muscle
(Elsevier, 2011)Antidepressants, including selective serotonin reuptake inhibitors (SSRIs), cause erectile dysfunction: however, the mechanism by which they cause erectile function is unclear. We investigated the reactivity of the corpus ... -
Chronic administration of imipramine but not agomelatine and moclobemide affects the nitrergic relaxation of rabbit corpus cavernosum smooth muscle
(Elsevier, 2013)Sexual dysfunction is a common and underestimated effect of antidepressants. However, the mechanism by which these drugs cause erectile dysfunction is unclear. We investigated the reactivity of the corpus cavernosum of ... -
Chronic moderate alcohol consumption induces iNOS expression in the penis: An immunohistochemical study
(Tubitak Scientific & Technical Research Council Turkey, 2014)Aim: To investigate the effect of moderate alcohol consumption on metabolic alterations, inducible nitric oxide synthase (iNOS), immunohistochemical distribution, and morphological damage to penile erectile tissue in rats. ... -
Comparison of endothelial function of coronary artery bypass grafts in diabetic and nondiabetic patients: Which graft offers the best?
(Turkish Soc Cardiology, 2015)Objective: Diabetes associated endothelial dysfunction, which determines both long and short term graft patency, is not uniform in all coronary artery bypass surgery (CABG) grafts. Herein this study, we aimed to investigate ... -
Comparison of Keratometric Data Obtained by Automated Keratometer, Dicon CT 200, Allegro Topolyzer, and Pentacam
(Slack Inc, 2012)PURPOSE: To compare the keratometric values measured by the automated keratometer, two Placido-based computerized topography systems (Dicon CT 200 [Vismed Inc] and Allegro Topolyzer [WaveLight Inc]), and Scheimpflug analysis ... -
A comparison of the effects of different classes of antidepressants on penile constitutive nitric oxide synthase of male rats
(Elsevier Science Bv, 2012)[No Abstract Available] -
Early administration of milrinone ameliorates lung and kidney injury during sepsis in juvenile rats
(Wiley, 2022)Background A sepsis model was created, induced by cecal ligation and puncture (CLP), in juvenile rat groups. Milrinone (MIL), which is known to have a modulatory effect on pro-inflammatory cytokines, was administered to ... -
The effect of a selective neuronal nitric oxide synthase inhibitor 3-bromo 7-nitroindazole on spatial learning and memory in rats
(Pergamon-Elsevier Science Ltd, 2015)Since the discovery of nitric oxide (NO) as a neuronal messenger, its way to modulate learning and memory functions is subject of intense research. NO is an intercellular messenger in the central nervous system and is ... -
Effect of harmane, an endogenous beta-carboline, on learning and memory in rats
(Pergamon-Elsevier Science Ltd, 2013)Our aim was to investigate the effects of acute harmane administration upon learning and memory performance of rats using the three-panel runway paradigm and passive avoidance test. Male rats received harmane (2.5, 5, and ... -
The effect of oral administration of monosodium glutamate on epileptogenesis in infant rats
(John Libbey, 2020)Aim: Glutamate is an excitatory neurotransmitter that is widely distributed throughout the brain. An increase in glutamate concentration or sensitivity of glutamate receptors triggers neurodegenerative diseases, epilepsy ... -
THE EFFECT OF QUERCETIN AND QUERCETIN-3-D-XYLOSIDE ON BREAST CANCER PROLIFERATION AND MIGRATION
(Dokuz Eylul Univ Inst Health Sciences, 2022)Background and Purpose: The aim of this study is to investigate the migration, wound healing, colony formation, and cytotoxic effects of Quercetin-3-D-xyloside (reynoutrin), a quercetin derivative, in breast cancer cells ... -
Effect of resveratrol on BDNF in a chronic unpredictable mild stress model: an immunohistochemical study
(Elsevier Science Bv, 2012)[No Abstract Available] -
Effect of resveratrol on penile neuronal and endothelial nitric oxide synthase expression in chronic unpredictable mild stress depression model
(Elsevier Science Bv, 2015)[No Abstract Available] -
Effect of U-92032, T-Type Ca(2+)Channel Blocker, on Rats with Genetic Absence Epilepsy
(Karger, 2020)Introduction:Absence epilepsy is associated with diffuse spike-and-wave discharges (SWD) on the electroencephalogram (EEG). Recent studies have demonstrated that the primary somatosensory cortex is also implicated in the ... -
Effects of acute topiramate administration on post-traumatic stress disorder in rats
(Cukurova Univ, Fac Medicine, 2022)Purpose: The aim of this study was to investigate the effects of acute systemic topiramate administration on anxiety index and freezing time, plasma estrogen and progesterone levels, and salivary gland immunoglobulin A in ... -
The Effects of Agomelatine Treatment on Lipopolysaccharide-Induced Septic Lung Injuries in Rats
(Aves, 2021)Objective: We designed an experimental model of sepsis in rats to investigate the effects of agomelatine (AGO) on lung tissues using molecular and histopathological methods. Materials and Methods: In our experimental model, ... -
Effects of chronic etanercept, a TNF-alpha inhibitor, on cognitive deficits in diabetic rats
(Elsevier Science Bv, 2013)[No Abstract Available]