Yazar "Aral, Cenk" için Fen Edebiyat Fakültesi Koleksiyonu listeleme
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Association of ACP1 genotypes and clinical parameters in patients with metabolic syndrome
Akkiprik, Mustafa; Özdemir Sertoğlu, Filiz; Çaglayan, Sinan; Aral, Cenk; Özışık, Gökhan; Atabey, Zebra; Özer, Sıdıka Ayşe (Tubitak Scientific & Technical Research Council Turkey, 2011)Aim: Acid phosphatase locus 1 (ACP1) encodes a polymorphic enzyme and has potential implications for the development of metabolic syndrome (MS) by altering insulin sensitivity. The aim of this study was to determine whether ... -
Does the mitochondrial genome much more stabile in the aggressive papillary thyroid cancers ('PTCs)? - the preliminary findings
Aral, Cenk; Gözü, Hülya İliksu; Sarıkaya, S.; Gül, A. Ege; Özçelik, S.; Bircan, Rifat (Wiley, 2018)[No Abstract Available] -
Impact of glucocorticoid receptor gene (NR3C1) polymorphisms in Turkish patients with metabolic syndrome
Kaya, Zeki; Çaglayan, S.; Akkiprik, Mustafa; Aral, Cenk; Özışık, Gökhan; Özata, M.; Özer, A. (Springer, 2016)Background The metabolic syndrome (MetS) is characterized by a cluster of metabolic factors, including insulin resistance and type-2 diabetes, abdominal obesity, dyslipidemia, hypertension and microalbuminuria. Impaired ... -
Investigation of relationship of the mitochondrial DNA 16189 T > C polymorphism with metabolic syndrome and its associated clinical parameters in Turkish patients
Aral, Cenk; Akkiprik, Mustafa; Çaglayan, Sinan; Atabey, Zehra; Özışık, Gökhan; Bekiroglu, Nuray; Özer, Ayşe (Hellenic Endocrine Soc, 2011)OBJECTIVE: Mitochondrial DNA (mtDNA) polymorphisms have been implicated in the pathophysiology of human diseases. Among them, a T>C nucleotide transition on the 16189 nucleotide position of mtDNA has been studied in several ... -
Melatonin reverses the oxidative stress and mitochondrial dysfunction caused by LETM1 silencing
Aral, Cenk; Demirkesen, Seyma; Bircan, Rifat; Yasar Şirin, Duygu (Wiley, 2020)LETM1 is a mitochondrial inner-membrane protein, which is encoded by a gene present in a locus of 4p, which, in turn, is deleted in the Wolf-Hirschhorn Syndrome, and is assumed to be related to its pathogenesis. The cellular ... -
Mitochondrial DNA common deletion is not associated with thyroid, breast and colorectal tumors in Turkish patients
Aral, Cenk; Akkiprik, Mustafa; Kaya, Handan; Ataizi-Celikel, Çiğdem; Çaglayan, Sinan; Özışık, Gökhan; Özer, Ayşe (Soc Brasil Genetica, 2010)Recently, efforts have been focused on mitochondrial DNA changes and their relation to human cancers. Among them, a 4977 bp deletion of mitochondrial DNA, named common deletion, has been investigated in several types of ... -
The Mitochondrial DNA Control Region Might Have Useful Diagnostic and Prognostic Biomarkers for Thyroid Tumors
Bircan, Rıfat; Ilıksu Gözü, Hülya; Ulu, Esra; Sarıkaya, Şükran; Gül, Aylin Ege; Şirin, Duygu Yaşar; Aral, Cenk (Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, 2019)The literature suggests that mitochondrial DNA (mtDNA) defects are associated with a large number of diseases including cancers. The role of mtDNA variations in thyroid cancer is a highly controversial topic. Therefore, ... -
A New Approach to DNA Isolation from Dileptid Ciliates (Ciliophora: Litostomatea: Rhynchostomatia)
Ural, Hilal; Bircan, Rifat; Aral, Cenk; Yıldız, İsmail; Şenler, Naciye Gülkız (Inst Zoology, Bas, 2020)Molecular diagnostic methods have been used to supplement morphological methods in taxonomy. In this study, we used molecular methods to diagnose populations of dileptid ciliates, which commonly occur in terrestrial and ... -
A new approach to DNA isolation from dileptid ciliates (Ciliophora: Litostomatea: Rhynchostomatia)
Ural, Hilal; Bircan, Rifat; Aral, Cenk; Yıldız, İsmail; Şenler, Naciye Gülkız (Bulgarska Akademiya na Naukite, 2020)Molecular diagnostic methods have been used to supplement morphological methods in taxonomy. In this study, we used molecular methods to diagnose populations of dileptid ciliates, which commonly occur in terrestrial and ... -
Novel binuclear antimony(III) halide complexes of 5-methoxy-2-mercaptobenzimidazole: synthesis, structural characterization, and biological studies
Öztürk, İbrahim İsmet; Yarar, Sinem; Gürgan, Muazzez; Ceyhan, Deniz; Panagiotou, Nikos; Tasiopoulos, Anastasios J.; Aral, Cenk (Taylor and Francis Ltd., 2020)The new binuclear antimony(III) complexes corresponding to the formulas [SbCl3(µ2-S)(MtMBZIM)2]2 (1), {[SbBr2(µ2-Br)(MtMBZIM)2]2·H2O} (2) and {[SbI2(µ2-I)(MtMBZIM)2]2·H2O} (3) (MtMBZIM: 5-methoxy-2-mercaptobenzimidazole) ... -
Prophylactic feeding with immune-enhanced diet ameliorates chemoradiation-induced gastrointestinal injury in rats
Atasoy, Beste M.; Deniz, Mustafa; Dane, Faysal; Özen, Zeynep; Turan, Pınar; Ercan, Feriha; Yegen, Berrak C.; Aral, Cenk (Taylor & Francis Ltd, 2010)Materials and methods: Forty-eight Sprague-Dawley rats were divided into control (C, n = 6), irradiation (IR, n = 14), fluoropyrimidine (5-FU, n = 14)-treated, IR + 5-FU (n = 14)-treated groups. Half of each irradiated ... -
Saliva extract of Dermacentor marginatus (Acari: Ixodidae) leads to apoptotic cell death
Demirkesen, S.; Kar, Sırrı; Aral, Cenk (Wiley, 2018)[No Abstract Available] -
siRNA mediated downregulation of LETM1 results in decreased expression of OPA1
Aral, Cenk; Şirin, Duygu Yaşar; Bircan, Rifat (Wiley-Blackwell, 2015)[No Abstract Available]