Kurum Yazarı "Topçu, Birol" PubMed İndeksli Yayın Koleksiyonu İçin Listeleme
-
Association of colon adenomas and skin tags: coincidence or coexistence?
Oran, Mustafa; Erfan, Gamze; Mete, Rafet; Yanık, Mehmet Emin; Yıldırım, Oğuzhan; Aydın, M.; Topçu, Birol (Verduci Publisher, 2014)OBJECTIVES: Skin tag (STs) are benign connective tissue tumors of the dermis. Some researchers have argued that there is a relationship between skin tag and colon polyps, although the physiopathological mechanisms underlying ... -
The association of TSH-receptor antibody with the clinical and laboratory parameters in patients with newly diagnosed Graves' hyperthyroidism: experience from a tertiary referral center including a large number of patients with TSH-receptor antibody-negative patients with Graves' hyperthyroidism
Zuhur, Sayid Shafi; Bilen, Ogün; Ağgül, Hünkar; Topçu, Birol; Çelikkol, Aliye; Elbüken, Gülşah (Via Medica, 2021)Introduction: Although the TSH-receptor antibody (TRAb) plays a central role in the pathogenesis of Graves' disease (GD), the association between TRAb at first diagnosis and clinical and laboratory parameters is not well ... -
Atherosclerosis, some serum inflammatory markers in psoriasis
Alpsoy, Şeref; Akyuz, A.; Erfan, Gamze; Akkoyun, Dursun Çayan; Topçu, Birol; Güzel, Savaş; Kulaç, Mustafa (Edizioni Minerva Medica, 2014)Aim. Psoriasis is an autoimmune inflammatory disease which is associated with increased inflammatory markers and atherosclerosis. We wanted to investigate whether there is a relationship between some inflammatory markers ... -
B-mode ultrasound assessment of carotid artery structural features in patients with normocalcaemic hyperparathyroidism
Elbüken, Gülşah; Aydın, Cihan; Öztürk, Beyza Olcay; Aykaç, Hüseyin; Topçu, Birol; Zuhur, Sayid Shafi (Via Medica, 2023)Introduction: Normocalcaemic hyperparathyroidism is a condition first defined in 2008, characterized by normal se- rum calcium and high parathormone levels. Although normocalcaemic hyperparathyroidism is considered to have ... -
Can low brain-derived neurotrophic factor levels be a marker of the presence of depression in obese women?
Güzel, Eda Çelik; Bakkal, Esra; Güzel, Savaş; Eroğlu, Hasan Emre; Acar, Ayşe; Küçükyalçın, Volkan; Topçu, Birol (Dove Medical Press Ltd, 2014)Objective: Depression is a common condition in obese women that can result in severe impairment of their physical and social functioning. A deficiency of brain-derived neurotrophic factor (BDNF) is involved in the mechanism ... -
Cardioprotective effects of fish omega-3 fatty acids on doxorubicin-induced cardiotoxicity in rats
Uygur, Ramazan; Aktaş, Cevat; Tülübaş, Feti; Alpsoy, Şeref; Topçu, Birol; Özen, Oğuz Aslan (Sage Publications Ltd, 2014)The aim of this study was to investigate the protective effects of fish omega-3 (n-3) fatty acids on doxorubicin (DOX)-induced acute cardiotoxicity. A total of 24 rats were divided into three groups: control, DOX-treated, ... -
Carotid arteries and vertebrobasilary system intracranial stenosis correlates with multi vessel coronary artery disease
Özçağlayan, Ömer; Kurtoğlu Özçağlayan, Tuğba İlkem; Özkaramanlı Gür, Demet; Gumusel, H. K.; Topçu, Birol; Ünal, A. (Comenius Univ, 2019)BACKGROUND: The goal of this study was to show the importance of the identifying potential carotid and vertebrobasilar stenosis with Computed Tomography Angiography (CTA) in severe coronary artery disease. METHODS: In 109 ... -
CD4(+), CD25(+), FOXP3(+) T Regulatory Cell Levels in Obese, Asthmatic, Asthmatic Obese, and Healthy Children
Donma, Mustafa Metin; Karasu, Erkut; Özdilek, Burcu; Turgut, Burhan; Topçu, Birol; Nalbanto?lu, Burçin; Donma, Orkide (Springer/Plenum Publishers, 2015)The aim of this prospective case control study is to determine CD4(+), CD25(+), and FoxP3(+) T regulatory cells (Tregs) and T helper cells (Ths) in obese, asthmatic, asthmatic obese, and healthy children. Obese (n = 40), ... -
Clinical usefulness of red cell distribution width to angiographic severity and coronary stent thrombosis
Erdem, Aysun; Ceylan, Ufuk Sadık; Esen, Aycan; Zencirci, Ertugrul; Topçu, Birol; Özden, Kivilcim; Yesilcimen, Kemal (Dove Medical Press Ltd, 2016)Background: Red cell distribution width (RDW) is a quantitative measurement and shows heterogeneity of red blood cell size in peripheral blood. RDW has recently been associated with cardiovascular events and cardiovascular ... -
Copeptin as a Novel Biomarker in Nocturnal Enuresis
Nalbantoğlu, Burçin; Yazıcı, Cenk Murat; Nalbantoğlu, Ayşin; Güzel, Savaş; Topçu, Birol; Güzel, Eda Çelik; Mintaş, Nuriye Ece (Elsevier Science Inc, 2013)OBJECTIVE To investigate the relation between copeptin, arginine vasopressin (AVP), and nocturnal enuresis (NE). METHODS Forty-four patients with NE and 44 healthy children aged between 6 and 14 years were enrolled. Patients ... -
Distinct temperament and character profiles in first onset vitiligo but not in alopecia areata
Erfan, Gamze; Albayrak, Yakup; Yanık, Mehmet Emin; Öksüz, Özden; Tasolar, Kaan; Topçu, Birol; Ünsal, Cüneyt (Wiley, 2014)Alopecia areata (AA) and vitiligo (V) are diseases that are correlated with psychiatric disorders before, during and after diagnosis. The Temperament and Character Inventory (TCI) is a well-established approach for ... -
Does hyperbaric oxygen therapy reduce the effects of ischemia on colonic anastomosis in laparoscopic colon resection?
Emir, Seyfi; Gürdal, Sibel Özkan; Sözen, Selim; Bali, İlhan; Yeşildağ, Ebru; Çelik, Atilla; Topçu, Birol; Güzel, Savaş (Edizioni Luigi Pozzi, 2016)BACKGROUND: An increase in intra-abdominal pressure causes a decrease in the splanchnic blood flow and the intramucosal pH of the bowel, as well as increasing the risk of ischemia in the colon. The aim of the present study ... -
The effect of gender on response to antithyroid drugs and risk of relapse after discontinuation of the antithyroid drugs in patients with Graves' hyperthyroidism: a multicentre study
Zuhur, Sayid Shafi; Yıldız, İsmail; Altuntaş, Yüksel; Bayraktaroğlu, Taner; Erol, Selvinaz; Şahin, Serdar; Kadıoğlu, Pınar; Elbüken, Gülşah; Topçu, Birol (Via Medica, 2020)Introduction: The outcome of medical treatment in patients with Graves' disease (GD) is generally difficult to predict. In this study, we examined the hypothesis that gender may affect the outcome of treatment with antithyroid ... -
Effect of lifestyle modifications on diastolic functions and aortic stiffness in prehypertensive subjects: a prospective cohort study
Alpsoy, Şeref; Oran, Mustafa; Topçu, Birol; Akyüz, Aydın; Akkoyun, Dursun Çayan; Değirmenci, Hasan (Aves, 2013)Objective: Prehypertension is one of the primary causes of major cardiovascular events independent from other cardiovascular risk factors. The aim of the study was to evaluate the effect of therapeutic lifestyle modifications ... -
Effect of overweight on cardiac function in children
Alpsoy, Şeref; Akyüz, Aydın; Akkoyun, Dursun Çayan; Nalbanto?lu, Burçin; Topçu, Birol; Değirmenci, Hasan; Donma, Mustafa Metin (Turkish Soc Cardiology, 2013)Objectives: It is known that obesity is related to heart failure. Asymptomatic left ventricular diastolic dysfunction (LVDD) is associated with the development of heart failure. The relationship between subclinical LVDD ... -
Effectiveness of the diagnostic pathway of BLES: could it be safely used as a therapeutic method in selected benign Lesions?
Kurtoğlu Özçağlayan, Tuğba İlkem; Gürdal, Sibel Özkan; Öznur, Meltem; Özçağlayan, Ömer; Doğru, Mücahit; Topçu, Birol (Turkish Soc Radiology, 2019)PURPOSE In this study, we aimed to investigate the breast lesion excision system (BLES) as a tool and a practical alternative technique to surgical biopsy and other percutaneous biopsy methods for spicious lesions. We also ... -
The effects of onion (Allium cepa) extract on doxorubicin-induced apoptosis in aortic endothelial cells
Alpsoy, Şeref; Uygur, Ramazan; Aktaş, Cevat; Topçu, Birol; Kanter, Mehmet; Erboğa, Mustafa; Gedikbaşı, Asuman (Wiley, 2013)The aim of this study was to investigate the effects of onion (Allium cepa) extracts (ACE) on doxorubicin (DOX)-induced apoptosis in aortic endothelial cells. The rats in the ACE-pretreated group were given a daily dose ... -
The effects of topical treatment with curcumin on burn wound healing in rats
Kulaç, Mustafa; Aktaş, Cevat; Tülübaş, Feti; Uygur, Ramazan; Kanter, Mehmet; Erboğa, Mustafa; Özen, Oğuz Aslan; Ceber, Mehmet; Topçu, Birol (Springer, 2013)The present study was designed to determine the role of topical treatment with curcumin (Cur) on burn wound healing in rats. The Wistar-albino rats were randomly allotted into one of three experimental groups: 4th, 8th and ... -
Evaluation of Serum Endocan Levels in Sensorineural Hearing Loss
Gültekin, Erdoğan; Ersözlü, Tolga; Demirel, Oral Burak; Kaymaz, Özlem; Topçu, Birol; Çiftçi, Zafer (Aves, 2019)OBJECTIVES: The aim of this study was to reveal the possible role of endothelial dysfunction in sensorineural hearing loss (SNHL) by determining the serum endocan levels of patients with varying degrees of SNHL. MATERIALS ... -
External Validation of the GREAT Score in Turkish Patients with Graves' Hyperthyroidism Treated with the Titration Regimen Method of Antithyroid Drugs: A Multicenter Study
Zuhur, Sayid Shafi; Elbüken, Gülşah; Yıldız, İsmail; Kadıoğlu, Pınar; Erol, Selvinaz; Şahin, Serdar; Altuntaş, Yüksel (Georg Thieme Verlag Kg, 2019)Recently, the Graves & apos; Recurrent Events After Therapy score (GREAT) was proposed as a useful tool to predict relapse before starting antithyroid drugs (ATD) in patients with Graves & apos; disease (GD). Therefore, ...