Kurum Yazarı "Mutlu, Levent Cem" PubMed İndeksli Yayın Koleksiyonu İçin Listeleme
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Airway inflammatory markers in chronic obstructive pulmonary disease patients and healthy smokers
Hacievliyagil, S. S.; Mutlu, Levent Cem; Temel, İlkbal (Medknow Publications & Media Pvt Ltd, 2013)Background: Cigarette smoke with its toxic ingredients leads to chronic inflammations in the airways. Objectives: In this study, the effect of cigarette smoke on the levels of inflammatory markers, interleukin-6 (IL-6), ... -
Assessment of Palliative Care in Lung Cancer in Turkey
Bülbül, Y.; Özlu, T.; Arınç, Sibel; Özyürek, Berna A.; Günbatar, Hülya; Şentürk, Ayşegül; Talay, F.; Mutlu, Levent Cem (Karger, 2017)Objective: To investigate the symptoms of lung cancer in Turkey and to evaluate approaches to alleviate these symptoms. Subjects and Methods: This study included 1,245 lung cancer patients from 26 centers in Turkey. ... -
Association Between Serum Fetuin-A levels, Carotid Artery Stiffness, and Intima-Media Thickness in Patients With Normotensive Obstructive Sleep Apnea Syndrome
Akyüz, Aydın; Oran, Mustafa; Alpsoy, Şeref; Mutlu, Levent Cem; Akkoyun, Dursun Çayan; Güzel, Savaş; Alp, Recep (Sage Publications Inc, 2014)Increased carotid intima-media thickness (cIMT) and stiffness, reflecting subclinical atherosclerosis, are associated with obstructive sleep apnea syndrome (OSAS). The relationship between serum fetuin-A, which inhibits ... -
Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with COPD
Aydın, Murat; Altıntaş, Nejat; Mutlu, Levent Cem; Bilir, Bülent; Oran, Mustafa; Tülübaş, Feti; Gürel, Ahmet (Wiley, 2017)IntroductionAsymmetric dimethylarginine (ADMA) and nitric oxide (NO) show their mechanism of action reciprocally, the balance between these molecules contributes to the tight regulation of airways tone and function. ... -
Carotid intima-media thickness in chronic obstructive pulmonary disease and survival: A multicenter prospective study
Gulbas, Gazi; Turan, Onur; Sarıoğlu, Nurhan; Diken, Özlem Ercen; Ogan, Nalan; Kadioglu, Esra Ekbic; Suerdem, Mecit; Mutlu, Levent Cem (Wiley, 2019)Introduction Chronic obstructive pulmonary disease (COPD) is associated with increased cardiovascular morbidity and mortality. Carotid intima-media thickness (CIMT) is a noninvasive method assessing atherosclerosis. Objective ... -
Childhood asthma and vitamin D deficiency in Turkey: is there cause and effect relationship between them?
Uysalol, Metin; Mutlu, Levent Cem; Saraçoğlu Varol, Gamze; Karasu, Erkut; Güzel, Savaş; Kayaoğlu, Semra; Uzel, Nedret (Bmc, 2013)Background: Epidemiological studies show that vitamin D deficiency and insufficiency are common worldwide and associated with many diseases including asthma. Our aim was to evaluate vitamin D insufficiency and its clinical ... -
The concordance of manuel (visual) scoring and automatic analysis in sleep staging
Öztürk, Önder; Mutlu, Levent Cem; Sağcan, Gülseren; Deniz, Yüksel; Çuhadaroğlu, Çağlar (Turkish Assoc Tuberculosis & Thorax, 2009)Full night polysomnography (PSG) remains the gold standard diagnostic test for the evaluation of sleep and the detection of sleep disorders. The computer-assisted scoring methods have been developed to accelerate the ... -
Desquamative interstitial pneumonia: Risk factors, laboratory and bronchoalveolar lavage findings, radiological and histopathological examination, clinical features, treatment and prognosis
Diken, Özlem Ercen; Şengül, Aysun; Beyan, Ayse Coskun; Ayten, Omer; Mutlu, Levent Cem; Okutan, Oguzhan (Spandidos Publ Ltd, 2019)Desquamative interstitial pneumonia is a type of smoking-associated major idiopathic interstitial pneumonia, which is characterized by accumulation of alveolar macrophages in alveolar lumens and septa and develops secondary ... -
Effect of CPAP on New Endothelial Dysfunction Marker, Endocan, in People With Obstructive Sleep Apnea
Altıntaş, Nejat; Mutlu, Levent Cem; Akkoyun, Dursun Çayan; Aydın, Murat; Bilir, Bülent; Yılmaz, Ahsen; Malhotra, Atul (Sage Publications Inc, 2016)Obstructive sleep apnea (OSA) is associated with increased cardiovascular (CV) morbidity and mortality. Endocan is a surrogate endothelial dysfunction marker that may be associated with CV risk factors. In this study, we ... -
Expert Opinion on Practice Patterns in Mild Asthma After the GINA 2019 Updates: A Major Shift in Treatment Paradigms from a Long-Standing SABA-Only Approach to a Risk Reduction-Based Strategy with the Use of Symptom-Driven (As-Needed) Low-Dose ICS/LABA
Özşeker, Zeynep Ferhan; Aksu, Kurtuluş; Mutlu, Levent Cem; Mutlu, Pınar; Öztürk, Can (Current Medicine Group, 2022)Purpose of Review This expert opinion, prepared by a panel of chest disease specialists, aims to review the current knowledge on practice patterns in real-life management of mild asthma and to address the relevant updates ... -
Growth Differentiation Factor-15 Is a Novel Biomarker Predicting Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Mutlu, Levent Cem; Altıntaş, Nejat; Aydın, Murat; Tülübaş, Feti; Oran, Mustafa; Küçükyalçın, Volkan; Kaplan, Gizem; Gürel, Ahmet (Springer/Plenum Publishers, 2015)Exacerbations in chronic obstructive pulmonary disease (COPD) reduce quality of life and are associated with a more rapid deterioration of the disease. Growth differentiation factor-15 (GDF-15) is a novel candidate ... -
Quantitative evaluation of computed tomography findings in patients with pulmonary embolism: the link between D-Dimer level and thrombus volume
Sasani, Hadi; Mutlu, Levent Cem (Associacao Medica Brasileira, 2021)OBJECTIVE: To investigate the correlation of D-dimer levels and computed tomography properties of pulmonary embolism. METHODS: A total of 58 treated patients with diagnosis of properties of pulmonary embolism were ... -
Reduction Mammaplasty Effect on Pulmonary Function and Arterial Blood Gas in the Overweight Female
Ceber, Mehmet; Yüksek, Adnan; Mutlu, Levent Cem; Bali, İlhan; Topçu, Birol (Springer, 2015)This study sought to prospectively determine whether reduction mammaplasty improves the results of pulmonary function tests (PFTs) and arterial blood gas (ABG) measurements among overweight or obese women with macromastia ... -
Relationship between plasma chemerin levels and disease severity in COPD patients
Boyuk, Banu; Güzel, Eda Çelik; Atalay, Hande; Güzel, Savaş; Mutlu, Levent Cem; Küçükyalçın, Volkan (Wiley, 2015)Background and AimsChronic inflammation of the lung is a characteristic finding in chronic obstructive pulmonary disease (COPD). The protein chemerin has been identified in inflammatory fluid and in inflamed tissues. This ... -
The serum copeptin levels in obstructive sleep apnea patients with prehypertensive
Akkoyun, Dursun Çayan; Akyüz, Aydın; Tülübaş, Feti; Altıntaş, Nejat; Alpsoy, Şeref; Mutlu, Levent Cem; Alp, Recep (Verduci Publisher, 2015)OBJECTIVE: Copeptin is a precursor of AVP, an antidiuretic hormone, plays a pivotal role in the maintenance of cardiovascular homeostasis. Obstructive sleep apnea syndrome (OSAS) is related to cardiovascular disease. We ... -
Serum fetuin-A levels are associated with carotid intima-media thickness in patients with normotensive chronic obstructive pulmonary disease
Alpsoy, Şeref; Akyüz, Aydın; Mutlu, Levent Cem; Oran, Mustafa; Akkoyun, Dursun Çayan; Topçu, Birol; Guze, Savas (Via Medica, 2014)Background: There are contradictory reports about the relationship between fetuin-A and atherosclerotic process. Coronary artery disease is the most important cause of mortality in patients with chronic obstructive pulmonary ... -
Serum YKL-40 level is correlated with apnea hypopnea index in patients with obstructive sleep apnea syndrome
Mutlu, Levent Cem; Tülübaş, Feti; Alp, Recep; Kaplan, Gökhan; Yıldız, Zeynep Deniz; Gürel, A. (Verduci Publisher, 2017)OBJECTIVE: Obstructive sleep apnea syndrome (OSAS) has been associated with elevated biochemical markers of inflammation. Although the exact mechanism is unknown, both sleep deprivation and hypoxemia are believed to be ... -
Sleep disturbances in patients with lung cancer in Turkey
Bülbül, Yılmaz; Özlu, Tevfik; Arınç, Sibel; Akıncı Özyürek, Berna; Günbatar, Hülya; Şentürk, Ayşegül; Talay, Fahrettin; Mutlu, Levent Cem (Turkish Assoc Tuberculosis & Thorax, 2018)Introduction: Sleep quality is known to be associated with the distressing symptoms of cancer. The purpose of this study was to analyze the impact of cancer symptoms on insomnia and the prevalence of sleep-related problems ...