Kurum Yazarı "Gürel, Ahmet" PubMed İndeksli Yayın Koleksiyonu İçin Listeleme
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Anti-Apoptotic and Anti-Oxidant Effects of Caffeic Acid Phenethyl Ester on Cadmium-Induced Testicular Toxicity in Rats
Erboğa, Mustafa; Kanter, Mehmet; Aktaş, Cevat; Dönmez, Yeliz Bozdemir; Erboğa, Zeynep Fidanol; Aktaş, Emel; Gürel, Ahmet (Humana Press Inc, 2016)Cadmium (Cd) is a serious environmental and occupational contaminant and may represent a serious health hazard to humans and other animals. Cd is reported to induce the generation of reactive oxygen species, and induces ... -
Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with COPD
Aydın, Murat; Altıntaş, Nejat; Mutlu, Levent Cem; Bilir, Bülent; Oran, Mustafa; Tülübaş, Feti; Gürel, Ahmet (Wiley, 2017)IntroductionAsymmetric dimethylarginine (ADMA) and nitric oxide (NO) show their mechanism of action reciprocally, the balance between these molecules contributes to the tight regulation of airways tone and function. ... -
The Effects of Ferulic Acid Against Oxidative Stress and Inflammation in Formaldehyde-Induced Hepatotoxicity
Gerin, Fethullah; Erman, Hayriye; Erboğa, Mustafa; Şener, Ümit; Yılmaz, Ahsen; Seyhan, Hatice; Gürel, Ahmet (Springer/Plenum Publishers, 2016)This study was designed to elucidate the protective effects of ferulic acid (FA) on formaldehyde-induced hepatotoxicity by measuring some routine biochemical parameters, cytokine levels, and oxidative stress-related ... -
The Effects of Quercetin on Acute Lung Injury and Biomarkers of Inflammation and Oxidative Stress in the Rat Model of Sepsis
Gerin, Fethullah; Şener, Ümit; Erman, Hayriye; Yılmaz, Ahsen; Aydın, Bayram; Armutcu, Ferah; Gürel, Ahmet (Springer/Plenum Publishers, 2016)Experimental studies indicate that sepsis causes remote organ injury although the molecular mechanism has not been clearly defined. In this report, the role of oxidative damage, and inflammation on lung injury, following ... -
Evaluation of Paraoxonase and Arylesterase activities in patients with irritable bowel syndrome
Oran, Mustafa; Tülübaş, Feti; Mete, Rafet; Aydın, Murat; Sarıkaya, Hatice Gul; Gürel, Ahmet (Pakistan Medical Assoc, 2014)The aims of the present study were to evaluate oxidative status, by investigating the serum Paraoxonase/Arylesterase (PON/ARE) activities along with conjugated dienes in patients with IBS and controls and to confirm the ... -
Growth Differentiation Factor-15 Is a Novel Biomarker Predicting Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Mutlu, Levent Cem; Altıntaş, Nejat; Aydın, Murat; Tülübaş, Feti; Oran, Mustafa; Küçükyalçın, Volkan; Kaplan, Gizem; Gürel, Ahmet (Springer/Plenum Publishers, 2015)Exacerbations in chronic obstructive pulmonary disease (COPD) reduce quality of life and are associated with a more rapid deterioration of the disease. Growth differentiation factor-15 (GDF-15) is a novel candidate ... -
Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome
Tülübaş, Feti; Oran, Mustafa; Mete, Rafet; Turan, Filiz; Yılmaz, Ahsen; Yıldız, Zeynep Deniz; Gürel, Ahmet (Tubitak Scientific & Technical Research Council Turkey, 2014)Aim: Irritable bowel syndrome (IBS), a functional disorder of the bowel, has been thought to result from immune activation. The aim of this study was to evaluate macrophage migration inhibitory factor (MMIF) and monocyte ... -
Neutrophil/lymphocyte ratio in obese adolescents
Aydın, Murat; Yılmaz, Ahsen; Donma, Mustafa Metin; Tülübaş, Feti; Demirkol, Muhammed; Erdoğan, Murat; Gürel, Ahmet (Kare Publ, 2015)OBJECTIVE: Obesity is a growing health problem in most of the developed countries. It is associated with many chronic diseases, affecting particularly endocrine and cardiovascular systems. Inflammation plays a key role in ... -
Plasma urotensin II and neurokinin B levels in acute myocardial infarction and stable coronary artery disease
Akkoyun, Dursun Çayan; Akyüz, Aydın; Alpsoy, Şeref; Gürel, Ahmet; Güler, Niyazi; Değirmenci, Hasan; Gurkan, Umit (Turkish Soc Cardiology, 2015)Objective: This aim of the study is to investigate whether there are possible plasma urotensin-II (U-II) and neurokinin B (NKB) level changes in patients with acute myocardial infarction (AMI) or not and plasma urotensin-II ... -
Possible association between vitamin D deficiency and restless legs syndrome
Oran, Mustafa; Ünsal, Cüneyt; Albayrak, Yakup; Tülübaş, Feti; Oğuz, Keriman; Avcı, Okan; Gürel, Ahmet (Dove Medical Press Ltd, 2014)Background and aim: Restless legs syndrome (RLS) is a distressing sleep disorder that occurs worldwide. Although there have been recent developments in understanding the -pathophysiology of RLS, the exact mechanism of the ... -
Protective Effect of Infliximab, a Tumor Necrosis Factor-Alfa Inhibitor, on Bleomycin-Induced Lung Fibrosis in Rats
Altıntaş, Nejat; Erboğa, Mustafa; Aktaş, Cevat; Bilir, Bülent; Aydın, Murat; Şengül, Aysun; Gürel, Ahmet; Topçu, Birol (Springer/Plenum Publishers, 2016)We aimed to investigate the preventive effect of Infliximab (IFX), a tumor necrosis factor (TNF)-alpha inhibitor, on bleomycin (BLC)-induced lung fibrosis in rats. Rats were assigned into four groups as follows: I-BLC ... -
The protective effects of omega-3 fatty acids on doxorubicin-induced hepatotoxicity and nephrotoxicity in rats
Tülübaş, Feti; Gürel, Ahmet; Oran, Mustafa; Topçu, Birol; Çağlar, Veli; Uygur, Emine (Sage Publications Inc, 2015)This study aims to evaluate the protective effects of omega-3 fatty acids (FAs) on doxorubicin (DOX)-induced hepatotoxicity and nephrotoxicity in rats. A total of 24 adult male Sprague Dawley rats were divided into three ... -
Quercetin ameliorates methotrexate-induced renal damage, apoptosis and oxidative stress in rats
Erboğa, Mustafa; Aktaş, Cevat; Erboğa, Zeynep Fidanol; Dönmez, Yeliz Bozdemir; Gürel, Ahmet (Taylor & Francis Ltd, 2015)Background: In the present study, the protective and therapeutic effects of quercetin (QE) on renal injury induced by methotrexate (MTX) have been examined. Materials and methods: A total of 24 male rats were divided into ... -
Relationship among MIF, MCP-1, viral loads, and HBs Ag levels in chronic hepatitis B patients
Güneş, Hayati; Mete, Rafet; Aydın, Murat; Topçu, Birol; Oran, Mustafa; Doğan, Mustafa; Gürel, Ahmet (Tubitak Scientific & Technical Research Council Turkey, 2015)Background/aim: To determine whether macrophage migration inhibitory factor (MIF) and monocyte chemoattractant protein-1 (MCP-1) levels in patients with hepatitis B (HB) are different than in normal individuals and whether ... -
Thymoquinone Ameliorates Cadmium-Induced Nephrotoxicity, Apoptosis, and Oxidative Stress in Rats is Based on its Anti-Apoptotic and Anti-Oxidant Properties
Erboğa, Mustafa; Kanter, Mehmet; Aktaş, Cevat; Şener, Ümit; Erboğa, Zeynep Fidanol; Dönmez, Yeliz Bozdemir; Gürel, Ahmet (Humana Press Inc, 2016)Cadmium (Cd), an environmental and industrial pollutant, generates free radicals responsible for oxidative stress. Cd can also lead to various renal toxic damage such as the proximal tubules and glomerulus dysfunction. ...