Kurum Yazarı "Avcı, Okan" PubMed İndeksli Yayın Koleksiyonu İçin Listeleme
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Breast cancer in young and very young women; Is age related to outcome?
Avcı, Okan; Tacar, Seher Yıldız; Seber, Erdoğan Selcuk; Yetişyiğit, Tarkan (Wolters Kluwer Medknow Publications, 2021)Background: Breast cancer in young women is associated with aggressive biology. We analyzed histopathological and clinical properties of breast cancer patients diagnosed at <= 40 years of age. Methods: Breast cancer patients ... -
Comprehensive Analysis of Prognostic Factors in Advanced Gastric Cancer Patients Treated with Chemotherapy
Çavdar, Eyyüp; İriağaç, Yakup; Avcı, Okan; Seber, Erdoğan Selçuk (Coll Physicians & Surgeons Pakistan, 2022)Objective: To evaluate the strongest prognostic factors in advanced gastric cancer. Study Design: Observational study. Place and Duration of Study: Department of Medical Oncology, Tekirdag Namik Kemal University, Tekirdag, ... -
The diagnostic contribution of magnetic resonance imaging in the detection of axillary metastasis after neoadjuvant chemotherapy
İriağaç, Yakup; Karaboyun, Kubilay; Çavdar, Eyyüp; Avcı, Okan; Kurtoğlu Özçağlayan, Tuğba İlkem; Öznur, Meltem; Şeber, Erdoğan Selçuk (Aepress Sro, 2022)Sentinel lymph node dissection (SLND) is a reliable method that provides axillary staging in clinical node-negative (cN0) breast cancer patients before neoadjuvant chemotherapy (NACT). However, it is not a standard method ... -
The effectiveness and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early-stage human epidermal growth factor receptor 2-positive breast cancer: Turkish Oncology Group study
Özdemir, Özlem; Zengel, Baha; Yıldız, Yaşar; Uluç, Başak Oyan; Çabuk, Devrim; Ozden, Ercan; Alacacıoğlu, Ahmet; Avcı, Okan (Lippincott Williams & Wilkins, 2022)In our study, we aimed to evaluate the pathological response rates and side effect profile of adding pertuzumab to the treatment of HER2+ locally advanced, inflammatory, or early-stage breast cancer. This study was conducted ... -
Efficacy and safety of trastuzumab emtansine in older patients with HER2-positive advanced breast cancer: a real-world study
Cil, İbrahim; Kücükarda, Ahmet; Atci, Muhammed Mustafa; Secmeler, Saban; Paksoy, Nail; Ferhatoglu, Ferhat; Aydiner, Adnan; Avcı, Okan (Sage Publications Ltd, 2022)Introduction: Ado-trastuzumab emtansine (T-DM1) is an antibody-drug conjugate and its survival advantage has been shown in advanced human epidermal growth factor receptor 2 (HER2)-positive breast cancer. However, clinical ... -
The influence of visual objects and music on anxiety levels of breast cancer patients scheduled to experience chemotherapy for the first time: a prospective randomized clinical study
İriağaç, Yakup; Çavdar, Eyyüp; Karaboyun, Kubilay; Avcı, Okan; Tuna, N.; Şeber, Erdoğan Selçuk (Springer Science and Business Media Deutschland GmbH, 2022)Objective: To investigate the influence of music together with visual objects as an ambiance in the waiting room on anxiety levels of breast cancer patients scheduled to receive chemotherapy in outpatient setting for the ... -
A logarithmic model for hormone receptor-positive and breast cancer patients treated with neoadjuvant chemotherapy
Seber, Erdoğan Selçuk; İriağaç, Yakup; Çavdar, Eyyüp; Karaboyun, Kubilay; Avcı, Okan; Yolcu, Ahmet; Gürdal, Sibel Özkan; Öznur, Meltem (Assoc Medica Brasileira, 2023)OBJECTIVE: The aim of this study was to investigate the predictive importance of the previously validated log(ER)*log(PgR)/Ki-67 predictive model in a larger patient population.METHODS: Patients with hormone receptor ... -
Mindfulness Among Medical Oncology Doctors and Its Relation With Burnout: Turkish Oncology Group (TOG) Study
Avcı, Okan; İriağaç, Yakup; Çavdar, Eyyüp; Seber, Erdoğan Selcuk (Lippincott Williams & Wilkins, 2021)PURPOSE: Medical oncology physicians have been identified as one of the main risk groups for the development of burnout. Mindfulness as being aware of the moment nonjudgmentally seems to be a protective factor against ... -
Performance characteristics of the simplified version of ankylosing spondylitis disease activity score (SASDAS)
Solmaz, Dilek; Yıldırım, Tülay; Avcı, Okan; Tomas, Nazmiye; Akar, Servet (Springer London Ltd, 2016)Various types of disease activity measures are available for axial spondyloarthritis (axSpA), and there is no gold standard for all individual patients. The ankylosing spondylitis disease activity score (ASDAS) is highly ... -
Possible association between vitamin D deficiency and restless legs syndrome
Oran, Mustafa; Ünsal, Cüneyt; Albayrak, Yakup; Tülübaş, Feti; Oğuz, Keriman; Avcı, Okan; Gürel, Ahmet (Dove Medical Press Ltd, 2014)Background and aim: Restless legs syndrome (RLS) is a distressing sleep disorder that occurs worldwide. Although there have been recent developments in understanding the -pathophysiology of RLS, the exact mechanism of the ... -
Prospective comparison of the value of CARG, G8, and VES-13 toxicity tools in predicting chemotherapy-related toxicity in older Turkish patients with cancer
Çavdar, Eyyüp; İriağaç, Yakup; Karaboyun, Kubilay; Avcı, Okan; Şeber, Erdoğan Selçuk (Elsevier, 2022)Background: In older patients with cancer, it is very important to choose the appropriate treatment because they are at high risk for chemotherapy toxicity. Our study investigated characteristics of Cancer and Aging Research ... -
Real-life comparison of the afatinib and first-generation tyrosine kinase inhibitors in nonsmall cell lung cancer harboring EGFR exon 19 deletion: a Turk Oncology Group (TOG) study
Bilgin, Burak; Sendur, Mehmet Ali; Yücel, Şebnem; Çelik, Emir; Özyükseler, Deniz Tataroğlu; Ayhan, Murat; Yalçın, Bülent; Avcı, Okan (Springer, 2021)Background The new second-generation tyrosine kinase inhibitors (TKIs) have superior survival outcome and worse toxicity profile when compared with first-generation TKIs according to the results of clinical trials. However, ... -
Soluble B7H3 level in breast cancer and its relationship with clinicopathological variables and T-cell infiltration
Avcı, Okan; Çavdar, Eyyüp; İriağaç, Yakup; Karaboyun, Kubilay; Çelikkol, Aliye; Kurtoğlu Özçağlayan, Tuğba İlkem; Öznur, Meltem; Gürdal, Sibel Özkan; Şeber, Erdoğan Selçuk (Termedia Publishing House Ltd, 2022)Aim of the study Although early diagnosis of breast cancer (BC) is often associated with a good prognosis, there is currently no biomarker with high sensitivity serving this purpose. B7H3, a recently identified member of ...