Kurum Yazarı "Aral, Cenk" PubMed İndeksli Yayın Koleksiyonu İçin Listeleme
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Impact of glucocorticoid receptor gene (NR3C1) polymorphisms in Turkish patients with metabolic syndrome
Kaya, Zeki; Çaglayan, S.; Akkiprik, Mustafa; Aral, Cenk; Özışık, Gökhan; Özata, M.; Özer, A. (Springer, 2016)Background The metabolic syndrome (MetS) is characterized by a cluster of metabolic factors, including insulin resistance and type-2 diabetes, abdominal obesity, dyslipidemia, hypertension and microalbuminuria. Impaired ... -
Investigation of relationship of the mitochondrial DNA 16189 T > C polymorphism with metabolic syndrome and its associated clinical parameters in Turkish patients
Aral, Cenk; Akkiprik, Mustafa; Çaglayan, Sinan; Atabey, Zehra; Özışık, Gökhan; Bekiroglu, Nuray; Özer, Ayşe (Hellenic Endocrine Soc, 2011)OBJECTIVE: Mitochondrial DNA (mtDNA) polymorphisms have been implicated in the pathophysiology of human diseases. Among them, a T>C nucleotide transition on the 16189 nucleotide position of mtDNA has been studied in several ... -
Melatonin reverses the oxidative stress and mitochondrial dysfunction caused by LETM1 silencing
Aral, Cenk; Demirkesen, Seyma; Bircan, Rifat; Yasar Şirin, Duygu (Wiley, 2020)LETM1 is a mitochondrial inner-membrane protein, which is encoded by a gene present in a locus of 4p, which, in turn, is deleted in the Wolf-Hirschhorn Syndrome, and is assumed to be related to its pathogenesis. The cellular ... -
Mitochondrial DNA common deletion is not associated with thyroid, breast and colorectal tumors in Turkish patients
Aral, Cenk; Akkiprik, Mustafa; Kaya, Handan; Ataizi-Celikel, Çiğdem; Çaglayan, Sinan; Özışık, Gökhan; Özer, Ayşe (Soc Brasil Genetica, 2010)Recently, efforts have been focused on mitochondrial DNA changes and their relation to human cancers. Among them, a 4977 bp deletion of mitochondrial DNA, named common deletion, has been investigated in several types of ... -
The Mitochondrial DNA Control Region Might Have Useful Diagnostic and Prognostic Biomarkers for Thyroid Tumors
Bircan, Rıfat; Ilıksu Gözü, Hülya; Ulu, Esra; Sarıkaya, Şükran; Gül, Aylin Ege; Şirin, Duygu Yaşar; Aral, Cenk (Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, 2019)The literature suggests that mitochondrial DNA (mtDNA) defects are associated with a large number of diseases including cancers. The role of mtDNA variations in thyroid cancer is a highly controversial topic. Therefore, ... -
Prophylactic feeding with immune-enhanced diet ameliorates chemoradiation-induced gastrointestinal injury in rats
Atasoy, Beste M.; Deniz, Mustafa; Dane, Faysal; Özen, Zeynep; Turan, Pınar; Ercan, Feriha; Yegen, Berrak C.; Aral, Cenk (Taylor & Francis Ltd, 2010)Materials and methods: Forty-eight Sprague-Dawley rats were divided into control (C, n = 6), irradiation (IR, n = 14), fluoropyrimidine (5-FU, n = 14)-treated, IR + 5-FU (n = 14)-treated groups. Half of each irradiated ...