Kurum Yazarı "Akpınar, Seval" PubMed İndeksli Yayın Koleksiyonu İçin Listeleme
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Defibrotide combined with triple therapy including posttransplant cyclophosphamide, low dose rabbit anti-t-lymphocyte globulin and cyclosporine is effective in prevention of graft versus host disease after allogeneic peripheral blood stem cell transplantation for hematologic malignancies
Akpınar, Seval; Kayıkçı, Ömür; Tekgündüz, Emre (Pergamon-Elsevier Science Ltd, 2022)Endothelial dysfunction and damage play important roles in the pathophysiology of graft versus host disease (GvHD) and hepatic venoocclusive disease/sinusoidal obstruction syndrome (VOD/SOS). Preliminary evidence suggests ... -
Effectiveness of defibrotide in the prevention of hepatic venooclusive disease among adult patients receiving allogeneic hematopoietic cell transplantation: A retrospective single center experience
Kayıkçı, Ömür; Akpınar, Seval; Tekgündüz, Emre (Pergamon-Elsevier Science Ltd, 2022)Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is one of the most life-threatening early complications following hematopoietic cell transplantation (HCT). Due to the high mortality rate of severe ... -
Efficacy and Safety of Ibrutinib Therapy in Patients with Chronic Lymphocytic Leukemia: Retrospective Analysis of Real-Life Data
Tombak, Anıl; Pepedil Tanrıkulu, Funda; Durusoy, Salih Sertaç; Dinçyürek, Hüseyin Derya; Kaya, Emin; Ümit, Elif Gülsüm; Ferhanoğlu, Burhan; Akpınar, Seval; Turgut, Burhan (Galenos Yayincilik, 2021)Objective: This study aimed to retrospectively evaluate the efficacy, safety, and survival outcome of single-agent ibrutinib therapy in chronic lymphocytic leukemia patients. Materials and Methods: A total of 136 patients ... -
Patients with severe coronavirus disease 2019 have high frequency of factor 5 Leiden and prothrombin gene mutations
Avcı, Burcu Altındağ; Doğan, Mustafa; Batar, Bahadır; Yıldırım, İlker; Serdal, Elif; Gezer, Sümbül; Onar, Çagatay L. (Lippincott Williams & Wilkins, 2023)We investigated the frequency of factor 5 Leiden (FVL) and prothrombin gene (PTG) mutations in patients with severe coronavirus disease 2019 (COVID-19). Our primary aim is to reveal whether these mutations are associated ... -
Procollagen C-proteinase enhancer-1 and renal failure in multiple myeloma
Bayrakçı, Nergiz; Özkan, Gülsüm; Akpınar, Seval; Ediz, Bartu; Yılmaz, Ahsen; Çelikkol, Aliye (Springer, 2022)Background Renal involvement is present in approximately 50% of multiple myeloma (MM) cases and is associated with a poor prognosis. Procollagen C-Proteinase Enhancer 1 (PCPE-1) is an extracellular matrix glycoprotein that ... -
Prospective registry of adult patients receiving therapeutic plasma exchange with a presumptive diagnosis of thrombotic microangiopathy (TMA): The Turkish hematology research and education group (ThREG)-TMA02 study
Akpınar, Seval; Tekgündüz, Emre; Esen, Ramazan; Yılmaz, Mehmet; Karakuş, Volkan; Vural, Filiz; Demirkan, Fatih (Pergamon-Elsevier Science Ltd, 2022)To understand who uses social media and how often they do so, we examined the personality traits that predict frequency of using a set of 10 different types of social media (e.g., social networks, blogs, virtual worlds). ... -
Real-Life Experience Regarding Clinical Characteristics and Treatment Outcome in Non-Cutaneous Peripheral T-Cell Lymphomas: A Multicenter Study of the Turkish Hematology Research and Education Group (ThREG)
Kayıkçı, Ömür; Mehtap, Ö.; Sarı, İ.; Demirkan, F.; Beyan, C.; Çetin, G.; Tekgündüz, E.; Akpınar, Seval (Turkish Society of Hematology, 2022)Objective: Peripheral T-cell lymphomas (PTCLs) are an uncommon and quite heterogeneous group of disorders, representing only 10%-15% of all non-Hodgkin lymphomas. Although both molecular and clinical studies have increased ... -
The Real-World Experience With Single Agent Ibrutinib in Relapsed/Refractory CLL
Akpınar, Seval; Doğu, Mehmet Hilmi; Çelik, Serhat; Ekinci, Ömer; Yönal Hindilerden, İpek; Dal, Mehmet Sinan; Altuntaş, Fevzi; Turgut, Burhan (Elsevier Inc., 2022)Introduction/Background: The emergence of novel agents targeting the B-cell receptor pathway and BCL-2 has significantly changed the therapeutic landscape of CLL. We evaluated the safety and efficacy of single-agent ibrutinib ... -
The role of oxidized phospholipids in COVID-19-associated hypercoagulopathy
Akpınar, Seval; Oran, Mustafa; Doğan, Mustafa; Çelikkol, Aliye; Erdem, İlknur; Turgut, Burhan (Verduci Editore s.r.l, 2021)OBJECTIVE: There is more pronounced hypercoagulation in COVID-19 infection than in other viral lung infections. Oxidized phospholipids (OxPLs) appear in COVID-19-infected lungs due to oxidative stress, after which they ...