Kurum Yazarı "Çalışkan, Tezcan" PubMed İndeksli Yayın Koleksiyonu İçin Listeleme
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Are Intervertebral Disc Tissue Cells Damaged When Attempting to Prevent Thrombus Formation Using Dabigatran, A New Oral Anticoagulant?
Kaplan, Necati; Karaarslan, Numan; Yılmaz, İbrahim; Yasar Şirin, Duygu; Akgün, Feride Sinem; Çalışkan, Tezcan; Özbek, Hanefi (Turkish Neurosurgical Soc, 2019)AIM: To investigate the effect of dabigatran, a new oral anticoagulant, on human primary cell cultures isolated from intact intervertebral disc tissue. MATERIAL and METHODS: Cell cultures were prepared from tissues obtained ... -
Are radio-contrast agents commonly used in discography toxic to the intact intervertebral disc tissue cells?
Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Şirin, Duygu Yaşar; Kaplan, Necati; Çalışkan, Tezcan; Ateş, Özkan (Wiley, 2019)In the literature, there have been no studies showing clear results on how radio-contrast pharmaceuticals would affect intact disc tissue cells. In this context, it was aimed to evaluate the effects of iopromide and gadoxetic ... -
Effect of Antithrombotic Therapy on Development of Acute Subdural Hematoma After Burr Hole Drainage of Chronic Subdural Hematoma
Yüksel, Mehmet Onur; Çevik, Serdar; Erdoğan, Barış; Tunçkale, Tamer; Katar, Salim; Işık, Semra; Evran, Şevket; Çalışkan, Tezcan (Turkish Neurosurgical Soc, 2020)AIM: To evaluate the relationship between the time from cessation of anticoagulant/antiplatelet medication to surgery and risk of postoperative acute subdural hematoma (ASDH) after burr hole drainage of chronic subdural ... -
The Effect of Matrix Metalloproteinase-3 on the Prognosis and Biological Behaviour of Meningiomas
Karaarslan, Numan; Gürbüz, Mehmet Sabri; Çalışkan, Tezcan; Ayan, Erdoğan; Vardar Aker, Fugen; Berkman, Mehmet Zafer (Turkish Neurosurgical Soc, 2016)AIM: To analyse the effect of MMP-3 (Matrix Metalloproteinase Enzyme-3)-one of the extracellular matrix proteins-on the prognosis and biological behaviour of meningiomas. MATERIAL and METHODS: 79 cases of meningioma that ... -
Effect of naproxen on proliferation and differentiation of primary cell cultures isolated from human cartilage tissue
Karaarslan, Numan; Batmaz, Ahmet Güray; Yılmaz, İbrahim; Özbek, Hanefi; Çalışkan, Tezcan; Şirin, Duygu Yaşar; Ateş, Özkan (Spandidos Publ Ltd, 2018)Non-steroidal anti-inflammatory drugs (NSAIDs) that are applied through oral, injectable or topical routes have been widely used in painful and inflammatory musculoskeletal diseases. The current study aimed to determine ... -
Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue
Çalışkan, Tezcan; Şirin, Duygu Yaşar; Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Akyuva, Yener; Ateş, Özkan; Şimşek, Abdullah Talha (Spandidos Publ Ltd, 2019)The aim of the present study was to investigate the effects of etanercept (ETA), a tumor necrosis factor (TNF) inhibitor, on human cell cultures prepared from intact intervertebral disc tissue. ETA is used as a treatment ... -
The effects of rivaroxaban, an oral anticoagulant, on human IVD primary cultures
Çalışkan, Tezcan; Akalan, Hande; Yılmaz, İbrahim; Karaarslan, Numan; Şirin, Duygu Yaşar; Özbek, Hanefi (Termedia Publishing House Ltd, 2022)Introduction: The present study aimed to investigate the potential effects of rivaroxaban, an oral anticoagulant that inhibits the effects of factor Xa, on intact intervertebral disc tissue cells and the extracellular ... -
Evaluation of the Effect of Daptomycin, a Glycopeptide Agent, on Intact Intervertebral Disc Tissue
Kaplan, Necati; Yılmaz, İbrahim; Karaarslan, Numan; Yasar Şirin, Duygu; Şimşek, Abdullah Talha; Çalışkan, Tezcan; Özbek, Hanefi (Turkish Neurosurgical Soc, 2019)AIM: To evaluate the effects of pre- and intra-operatively administered daptomycin (DAP) on the intact human primary intervertebral disc tissue cells. MATERIAL and METHODS: Primary cell cultures were established using ... -
The Impact of Various Breast Sizes of Women on Vertebral Column and Spinopelvic Parameters
Tunçkale, Tamer; Gürdal, Sibel Özkan; Çalışkan, Tezcan; Topçu, Birol; Yüksel, Mehmet Onur (Turkish Neurosurgical Society, 2021)AIM: To find out the anatomical changes in spine and pelvis, and the impact of various breast sizes of women on the quality of life. MATERIAL and METHODS: Sixty women with back pain volunteered to participate in this study. ... -
Intraabdominal Pseudocyst Developed after Ventriculoperitoneal Shunt: A Case Report
Ayan, Erdoğan; Tanriverdi, Halil İbrahim; Çalışkan, Tezcan; Senel, Ufuk; Karaarslan, Numan (Premchand Shantidevi Research Foundation, 2015)Abdominal pseudocyst is a rare complication developing after ventriculoperitoneal shunt treatment. It is more commonly seen particularly in children. The underlying pathogenesis may be associated with repeat revisions or ... -
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
Akgün, Feride Sinem; Şirin, Duygu Yaşar; Yılmaz, İbrahim; Karaarslan, Numan; Özbek, Hanefi; Şimşek, Abdullah Talha; Ateş, Özkan; Çalışkan, Tezcan (Spandidos Publ Ltd, 2019)The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti-pyretic and anti-spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells in vitro. After surgical ... -
Pain and neurogenic claudication control in lumbar stenosis, which is the most common cause of spinal surgery in the geriatric population
Yüksel, Mehmet Onur; Erdoğan, Barış; Usen, Ahmet; Tunçkale, Tamer; Çalışkan, Tezcan (Kare Publ, 2023)Objectives: The authors aim to present when to do physical therapy or surgery in geriatric patients with degenerative lumbar stenosis. Methods: The authors retrospectively analyzed 250 patients who underwent physical therapy ... -
Remote Cerebellar Haemorrhage Occurring after Transcranial Pituitary Surgery
Karaarslan, Numan; Gürbüz, Mehmet Sabri; Çalışkan, Tezcan; Tunckale, Tamer (Premchand Shantidevi Research Foundation, 2017)Post supratentorial and spinal surgeries, in rare cases, Remote Cerebellar Haemorrhage (RCH) develops as a complication. Although the exact aetiology of RCH remains uncertain, excessive drainage of the Cerebrospinal Fluid ... -
Systematic Evaluation of Promising Clinical Trials-Gene Silencing for the Treatment of Glioblastoma
Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Çalışkan, Tezcan; Topuk, Savas; Yasar Şirin, Duygu; Ateş, Özkan (Turkish Neurosurgical Soc, 2019)AIM: To systematically investigate the role of artificial small interfering RNA (SiRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field ...