Kurum Yazarı "Güzel, Savaş" PubMed İndeksli Yayın Koleksiyonu İçin Listeleme
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Implications of circulating irisin and Fabp4 levels in patients with polycystic ovary syndrome
Abalı, Remzi; Yüksel, İlkbal Temel; Yüksel, Mehmet Aytaç; Bulut, Berk; İmamoğlu, Metehan; Emirdar, Volkan; Çelik, Cem; Güzel, Savaş (Taylor & Francis Inc, 2016)The aim of the study was to evaluate the fatty acid-binding protein-4 (FABP4) and irisin concentrations in women with polycystic ovary syndrome (PCOS). Forty-nine women with PCOS, diagnosed according to Rotterdam criteria ... -
Increased Carotid Intima-Media Thickness and Endothelial Cell-Specific Molecule-1 (Endocan) Levels in Obese Children
Nalbantoğlu, Ayşin; Kızılca, Özgür; Güzel, Savaş; Emeksiz, Hamdi Cihan; Nalbanto?lu, Burçin (Sage Publications Inc, 2021)Obesity in children appears to be associated with increased risk of cardiovascular and metabolic diseases later in life. Early development of insulin resistance (IR) may lead to endothelial dysfunction and increased carotid ... -
Indices Used in Differentiation of Thalassemia Trait from Iron Deficiency Anemia in Pediatric Population: Are They Reliable?
Nalbanto?lu, Burçin; Güzel, Savaş; Büyükyalçın, Volkan; Donma, Mustafa Metin; Güzel, Eda Çelik; Nalbantoğlu, Ayşin; Özdilek, Burcu (Taylor & Francis Inc, 2012)Background: Iron deficiency (IDA) and beta thalassemia trait (TT) are the most common causes of hypochromia and microcytosis. Many indices have been defined to quickly discriminate these similar entities via parameters ... -
Inflammatory Mediators Across the Spectrum of Ankle-Brachial Index
Özkaramanlı Gür, Demet; Gür, Özcan; Güzel, Savaş; Akyüz, Aydın; Gürkan, Selami; Alpsoy, Şeref; Koç, Fatma (Japan Atherosclerosis Soc, 2019)Aim: Peripheral artery disease (PAD) is a manifestation of atherosclerosis with poor prognosis. It is generally complicated by vascular calcification, which is located either in the intima as patchy infiltrates; or ... -
Interleukin-33, matrix metalloproteinase-9, and tissue inhibitor of matrix metalloproteinase-1 in myocardial infarction
Güzel, Savaş; Serin, Ozden; Güzel, Eda Çelik; Büyük, Banu; Yılmaz, Guzin; Guvenen, Güvenç (Korean Assoc Internal Medicine, 2013)Background/Aims: Acute coronary syndrome (ACS) is characterized by increased inflammatory processes and endothelial activation. We investigated the association between ACS and inflammatory mediators and matrix-degrading ... -
Is meteorin-like (Metrnl) a novel biomarker to distinguish patients with obstructive sleep apnea (OSA) and patients with OSA at vascular risk
Altıntaş, Nejat; Fazlioğlu, Nevin; Güzel, Savaş; Yılmaz, Ahsen; Aydın, Cihan (Springer Heidelberg, 2023)PurposeMetrnl, a newly discovered adipokine with significant expression in white adipose tissue, promotes energy expenditure and contributes to the development of cardiovascular disorders. Endocan is a surrogate marker for ... -
Is subclinical hypothyroidism contributing dyslipidemia and insulin resistance in women with polycystic ovary syndrome?
Çelik, Cem; Abalı, Remzi; Taşdemir, Nicel; Güzel, Savaş; Yüksel, Aytac; Aksu, Erson; Yılmaz, Murat (Taylor & Francis Ltd, 2012)We aimed to analyze lipid parameters and determine the need for a 2-hour oral glucose tolerance test (OGTT) for the identification of IR and impaired glucose tolerance test (IGT) in subclinical hypothyroidism (SCH) women ... -
Measurement of salusin-beta without the addition of NP-40 or Tween-20 in coronary slow-flow phenomenon Reply
Akyüz, Aydın; Aydın, Fatma; Alpsoy, Şeref; Özkaramanlı Gür, Demet; Güzel, Savaş (Aves, 2020)[No Abstract Available] -
Midkine Levels and its Relationship with Atherosclerotic Risk Factors in Essential Hypertensive Patients
Güzel, Savaş; Cinemre, Fatma Behice Serinkan; Güzel, Eda Çelik; Küçükyalçın, Volkan; Kızıler, Ali Rıza; Çavuşoğlu, Coşkun; Aydemir, Birsen (Wolters Kluwer Medknow Publications, 2018)Background and Objectives: Hypertension (HT) is one of the risk factors associated with atherosclerosis. Midkine (MK) plays a role as a growth factor in various biologic and pathologic events. In some reports, MK expression ... -
No relationship between osteoprotegerin concentrations and endothelial dysfunction in non-obese women with and without polycystic ovary syndrome
Abalı, Remzi; Taşdemir, Nicel; Alpsoy, Şeref; Taşdemir, Ufuk Göker; Güzel, Savaş; Yüksel, Mehmet Aytaç; Yılmaz, Murat (Springer Heidelberg, 2015)To investigate the relationships of osteoprotegerin (OPG) concentrations to brachial artery flow-mediated vasodilation (FMD) and the carotid artery intima media thickness (CIMT) in polycystic ovary syndrome (PCOS). ... -
Novel imaging modalities in detection of cardiovascular involvement in ankylosing spondylitis
Özkaramanlı Gür, Demet; Özaltun, Derya Necmiye; Güzel, Savaş; Sarıfakıo?lu, Ayşe Banu; Akyüz, Aydın; Alpsoy, Şeref; Baykiz, Derya (Taylor & Francis Ltd, 2018)Objectives: The diagnosis of cardiovascular involvement in ankylosing spondylitis (AS) is usually delayed since conventional echocardiography relies mainly on the morphological alterations. The aim of this study was to ... -
Osteoprotegerin, leptin and IL-6: Association with silent myocardial ischemia in type 2 diabetes mellitus
Güzel, Savaş; Seven, Arzu; Kocaoglu, Ali; İlk, Banu; Güzel, Eda Çelik; Saraçoğlu Varol, Gamze; Çelebi, Asian (Sage Publications Ltd, 2013)Background: Diabetic patients often exhibit severe, asymptomatic coronary artery disease (CAD). The relationship between osteoprotegerin (OPG), inflammatory markers and silent myocardial ischemia remains to be elucidated. ... -
Protective effect of infliximab on ischemia/reperfusion injury in a rat ovary model: biochemical and histopathologic evaluation
Abalı, Remzi; Taşdemir, Nicel; Yüksel, Mehmet Aytaç; Güzel, Savaş; Öznur, Meltem; Nalbantoğlu, Burçin; Taşdemir, Ufuk Göker (Elsevier Science Bv, 2013)Objective: The aim of this study was to investigate the effect of infliximab on experimentally induced ovarian ischernia/reperfusion injury (IRi). Study design: A total of 42 female rats were equally divided into 6 ... -
Red Cell Distribution Width and Acute Complications of Diabetes
Atalay, Hande; Boyuk, B.; Ateş, Murat; Güzel, Savaş; Çelebi, A.; Ekizoğlu, İsmail (Editura Acad Romane, 2018)Context. Red cell distribution width (RDW) has been associated with type 2 diabetes (T2DM), however data in relation to diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar non-ketotic acidosis (HONK) remains unclear. ... -
Relationship between Levels of Brain-Derived Neurotrophic Factor and Metabolic Parameters in Patients with Type 2 Diabetes Mellitus
Boyuk, Banu; Değirmencioğlu, Şerife; Atalay, Hande; Güzel, Savaş; Acar, Ayşe; Çelebi, Aslan; Şimşek, Çağlar (Hindawi Ltd, 2014)Background and Aim. Studies have suggested that brain-derived neurotrophic factor (BDNF) plays a role in glucose and lipid metabolism and inflammation. The aim of this study was to evaluate the relationship between serum ... -
Relationship between Microfibrillar-Associated Protein 4 Levels and Subclinical Myocardial Damage in Chronic Kidney Disease
Kara, Sonat Pınar; Özkan, Gülsüm; Özkaramanlı Gür, Demet; Emeksiz, Gaye Kübra; Yılmaz, Ahsen; Bayrakçı, Nergiz; Güzel, Savaş (Karger, 2020)Introduction:Chronic kidney disease (CKD) is a widespread health problem, in which mortality is most frequently due to cardiovascular diseases. Microfibrillar-associated protein 4 (MFAP4) is an extracellular matrix protein. ... -
Relationship between plasma chemerin levels and disease severity in COPD patients
Boyuk, Banu; Güzel, Eda Çelik; Atalay, Hande; Güzel, Savaş; Mutlu, Levent Cem; Küçükyalçın, Volkan (Wiley, 2015)Background and AimsChronic inflammation of the lung is a characteristic finding in chronic obstructive pulmonary disease (COPD). The protein chemerin has been identified in inflammatory fluid and in inflamed tissues. This ... -
Relationship of serum salusin beta levels with coronary slow flow
Akyüz, Aydın; Aydın, Fatma; Alpsoy, Şeref; Özkaramanlı Gür, Demet; Güzel, Savaş (Aves, 2019)Objective: The pathophysiology of coronary slow flow (CSF) has not been clarified. Salusin-beta is released predominantly from the atheroma plaques and influences the pathophysiologic processes of atherosclerosis. Therefore, ... -
The role of novel cytokines in inflammation: Defining peripheral artery disease among patients with coronary artery disease
Özkaramanlı Gür, Demet; Güzel, Savaş; Akyüz, Aydın; Alpsoy, Şeref; Güler, Niyazi (Sage Publications Ltd, 2018)Coronary artery disease (CAD) patients with concomitant peripheral artery disease (PAD) experience more extensive and calcified atherosclerosis, greater lesion progression and more common coronary events compared to patients ... -
Role of sympathetic cotransmitter galanin on autonomic balance in heart failure: an active player or a bystander?
Özkaramanlı Gür, Demet; Sagbas, Miray; Akyüz, Aydın; Güzel, Savaş; Alpsoy, Şeref; Güler, Niyazi (Turkish Soc Cardiology, 2017)Objective: Galanin, a cotransmitter similar to neuropeptide Y (NPY), aggravates autonomic imbalance in systolic heart failure (HF) by attenuating vagal tonus after burst sympathetic activity. In animal HF models, galanin ...