Yazar "Doğan, Mustafa" için PubMed İndeksli Yayın Koleksiyonu listeleme
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Are the leading drugs against Staphylococcus aureus reallytoxic to cartilage?
Doğan, Mustafa; İşyar, Mehmet; Yılmaz, İbrahim; Bilir, Bülent; Şirin, Duygu Yaşar; Çakmak, Selami; Mahiroğulları, Mahir (Elsevier Science London, 2016)Many studies have shown that the toxic effects of local antibiotics on bone and cartilage limit orthopedic surgeons. In this study, we evaluated three antibacterial agents used locally to treat highly mortal and morbid ... -
Are treatment guides and rational drug use policies adequately exploited in combating respiratory system diseases?
Doğan, Mustafa; Mutiu, Levent C.; Yılmaz, İbrahim; Bilir, Bülent; Saraçoğlu Varol, Gamze; Yıldırım Güzelant, Aliye (Elsevier Science London, 2016)The aim of the present study was to increase awareness regarding the rational use of medicines. The data were obtained via the Material Resources Management System Module of the Ministry of Health. For the appropriateness ... -
Can transcription factors in the intervertebral disc of lopinavir/ritonavir prevent degeneration in the nucleus pulposus by mediating the regulation of inflammation through signaling pathways?
Yılmaz, I.; Akalan, Hande; Karaarslan, N.; Şirin, Duygu Yaşar; Kaplan, N.; Doğan, Mustafa; Özbek, H. (Verduci Publisher, 2022)OBJECTIVE: This study was con-ducted to examine whether lopinavir/ritonavir (Lop/r), an HIV protease inhibitor, can improve disc physiology and slow down intervertebral disc (IVD) degeneration through in vitro experimental ... -
Can transcription factors in the intervertebral disc of lopinavir/ritonavir prevent degeneration in the nucleus pulposus by mediating the regulation of inflammation through signaling pathways?
Yılmaz, İbrahim; Akalan, Hande; Karaarslan, Numan; Şirin, Duygu Yaşar; Kaplan, Nuray; Doğan, Mustafa; Ateş, Oğuz (Verduci Editore s.r.l, 2022)OBJECTIVE: This study was conducted to examine whether lopinavir/ritonavir (Lop/r), an HIV protease inhibitor, can improve disc physiology and slow down intervertebral disc (IVD) degeneration through in vitro experimental ... -
Coexistence of SARS-CoV-2 and cerebrovascular diseases: does COVID-19 positivity trigger cerebrovascular pathologies?
Ateş, Özkan; Yılmaz, İbrahim; Karaarslan, Numan; Ersöz, Emel; Kasim, Fatma Bahar Hacioglu; Doğan, Mustafa; Özbek, Hanefi (J Infection Developing Countries, 2022)The objectives of this study were to determine the prevalence of cerebrovascular diseases caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, and to assess the pharmacological agents used in ... -
Colistin nephrotoxicity increases with age
Balkan, İlker İnanç; Doğan, Mustafa; Durdu, Bülent; Batırel, Ayşe; Hakyemez, İsmail N.; Çetin, Birsen; Tabak, Fehmi (Informa Healthcare, 2014)Background: Colistin (COL) has become the backbone of the treatment of infections due to extensively drug-resistant (XDR) Gram-negative bacteria. The most common restriction to its use is acute kidney injury (AKI). Methods: ... -
Comparison of colistin monotherapy and non-colistin combinations in the treatment of multi-drug resistant Acinetobacter spp. bloodstream infections: A Multicenter retrospective analysis
Balkan, İlker İnanç; Batırel, Ayşe; Karabay, Oğuz; Ağalar, Canan; Akalın, Şerife; Alici, Özlem; Yılmaz, Hava; Doğan, Mustafa (Wolters Kluwer Medknow Publications, 2015)Objectives: To compare the efficacy of colistin (COL) monotherapy versus non-COL based combinations in the treatment of bloodstream infections (BSIs) due to multidrug resistant Acinetobacter spp.(MDR-A) . Materials and ... -
Decrease of left ventricular ejection fraction in severe illness patients due to COVID-19 may improve as the disease resolves
Demirkiran, Aykut; Onar, L. Ç.; Doğan, Mustafa (Turkiye Klinikleri, 2021)Background/aim: Increase in publications supporting myocardial involvement in the COVID-19 disease has led to need to gain insight into the the global burden of heart failure after pandemic. We examined the course of ... -
Evaluation of Empirical Antibiotic Treatment in Culture Negative Pyogenic Vertebral Osteomyelitis
Doğan, Mustafa; Şimşek, Abdullah Talha; Yılmaz, İbrahim; Karaarslan, Numan (Turkish Neurosurgical Soc, 2019)AIM: To investigate the efficacy of empirical antibiotic treatment in culture-negative pyogenic vertebral osteomyelitis (PVO) cases. MATERIAL and METHODS: The records of patients with culture-negative PVO who were treated ... -
False-positivity in diagnosis of brucellosis associated with Rev-1 vaccine
Güneş, Hayati; Doğan, Mustafa (Co-Action Publishing, 2013)[No Abstract Available] -
Gemella morbillorum endocarditis in a patient with a bicuspid aortic valve
Doğan, Mustafa; Topkaya, Aynur Eren; Alpsoy, Şeref; Gür, Özcan; Erdem, İlknur (Kare Publ, 2021)Gemella morbillorum is one of the rare causative microorganisms of endocarditis. We herein report a case of infective endocarditis in a patient with bicuspid aortic valve caused by G. morbillorum. Infective endocarditis ... -
Investigation of Factors Affecting Viral Clearance Time by Real-Time Polymerase Chain Reaction Method in Nasopharyngeal Swab Samples of COVID-19 Patients
Doğan, Mustafa; Çelikkol, Aliye; Yılmaz, Berna; Erdem, İlknur (Ankara Microbiology Soc, 2022)The coronavirus disease-2019 (COVID-19) pandemic continues to threaten the lives of millions of people. Viral shedding through the respiratory tract is the main risk factor for the transmission of the severe acute respiratory ... -
A novel combined index of D-dimer, fibrinogen, albumin, and platelet (FDAPR) as mortality predictor of COVID-19
Çelikkol, Aliye; Doğan, Mustafa; Güzel, Eda Çelik; Erdal, Berna; Yılmaz, A. (Wolters Kluwer Medknow Publications, 2022)Background: In coronavirus disease 2019 (COVID-19) caused by SARSCoV2 viruses, coagulation abnormalities are strongly correlated between disease severity and mortality risk. Aims: The aim was to search for new indices to ... -
A Novel Combined Index of D-Dimer, Fibrinogen, Albumin, and Platelet (FDAPR) as Mortality Predictor of COVID-19
Çelikkol, Aliye; Doğan, Mustafa; Güzel, Eda Çelik; Erdal, Berna; Yılmaz, A. (Wolters Kluwer Medknow Publications, 2022)Background: In coronavirus disease 2019 (COVID-19) caused by SARSCoV2 viruses, coagulation abnormalities are strongly correlated between disease severity and mortality risk. Aims: The aim was to search for new indices to ... -
Patients with severe coronavirus disease 2019 have high frequency of factor 5 Leiden and prothrombin gene mutations
Avcı, Burcu Altındağ; Doğan, Mustafa; Batar, Bahadır; Yıldırım, İlker; Serdal, Elif; Gezer, Sümbül; Onar, Çagatay L. (Lippincott Williams & Wilkins, 2023)We investigated the frequency of factor 5 Leiden (FVL) and prothrombin gene (PTG) mutations in patients with severe coronavirus disease 2019 (COVID-19). Our primary aim is to reveal whether these mutations are associated ... -
Profiles of multidrug-resistant organisms among patients with bacteremia in intensive care units: an international ID-IRI survey
El-Sokkary, Rehab; Uysal, Serhat; Erdem, Hakan; Kullar, Ravina; Pekok, Abdullah Umut; Amer, Fatma; Rello, Jordi; Doğan, Mustafa (Springer, 2021)Evaluating trends in antibiotic resistance is a requisite. The study aimed to analyze the profile of multidrug-resistant organisms (MDROs) among hospitalized patients with bacteremia in intensive care units (ICUs) in a ... -
Relationship among MIF, MCP-1, viral loads, and HBs Ag levels in chronic hepatitis B patients
Güneş, Hayati; Mete, Rafet; Aydın, Murat; Topçu, Birol; Oran, Mustafa; Doğan, Mustafa; Gürel, Ahmet (Tubitak Scientific & Technical Research Council Turkey, 2015)Background/aim: To determine whether macrophage migration inhibitory factor (MIF) and monocyte chemoattractant protein-1 (MCP-1) levels in patients with hepatitis B (HB) are different than in normal individuals and whether ... -
The role of oxidized phospholipids in COVID-19-associated hypercoagulopathy
Akpınar, Seval; Oran, Mustafa; Doğan, Mustafa; Çelikkol, Aliye; Erdem, İlknur; Turgut, Burhan (Verduci Editore s.r.l, 2021)OBJECTIVE: There is more pronounced hypercoagulation in COVID-19 infection than in other viral lung infections. Oxidized phospholipids (OxPLs) appear in COVID-19-infected lungs due to oxidative stress, after which they ... -
Self-reported antibiotic stewardship and infection control measures from 57 intensive care units: An international ID-IRI survey
El-Sokkary, Rehab; Erdem, Hakan; Kullar, Ravina; Pekok, Abdullah Umut; Amer, Fatma; Grgic, Svjetlana; Carevic, Biljana; Doğan, Mustafa (Elsevier Science London, 2022)We explored the self-reported antibiotic stewardship (AS), and infection prevention and control (IPC) activities in intensive care units (ICUs) of different income settings. A cross-sectional study was conducted using an ... -
Treatment of ventilator-associated pneumonia (VAP) caused by Acinetobacter: results of prospective and multicenter ID-IRI study
Erdem, Hakan; Çağ, Yasemin; Gencer, Serap; Uysal, Serhat; Karakurt, Zuhal; Harman, Rezan; Rello, Jordi; Doğan, Mustafa (Springer, 2020)Ventilator-associated pneumonia (VAP) due to Acinetobacter spp. is one of the most common infections in the intensive care unit. Hence, we performed this prospective-observational multicenter study, and described the course ...