Güncel Gönderiler: Scopus İndeksli Yayınlar Koleksiyonu
Toplam kayıt 4328, listelenen: 2381-2400
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Investigation of numerical solution for fourth-order nonlocal problem by the reproducing kernel method
(2011)This work investigates the approximate solution for fourth-order multi-point boundary value problem represented by linear integro-differential equation involving nonlocal integral boundary conditions by using the reproducing ... -
Forced Degradation Studies of Nateglinide by the First-Order Derivative Spectrophotometric Method and the Density Functional Theory of the Nateglinide Molecule
(Springer, 2022)Nateglinide (NAT) is an oral antihyperglycemic agent used for the treatment of noninsulin-dependent diabetes mellitus. We evaluated the NAT stability under various forced degradation tests (acidic, basic) and predicted the ... -
Structural, electronic, and spectroscopic study on 1,5-methanoazocino[4,3-b]indole synthesized by TFB-based route
(Springer International Publishing Ag, 2021)This work proposed a new route to synthesizing pharmaceutical important molecules just in three steps. This synthetic route provides an economical way for synthetic chemistry to get the key products concerning the biochemical ... -
An efficient studies on C-2 cyanomethylation of the indole synthesis: the electronic and spectroscopic characterization (FT-IR, NMR, UV-Vis), antioxidant activity, and theoretical calculations
(Elsevier, 2022)The direct cynamethylation with the development of catalyzed methodologies directed to 2-(cyanomethyl)indoles was reported by using tetrafluoro-1,4-benzoquinone (TFB) as the catalyst and it was synthesized in one step ... -
Cyanomethylation of 2,3,4,9-tetrahydro-1H-carbazol-1-one based on using two different reagents: Antioxidant activity and DFT studies
(Elsevier, 2022)C-2 and C-6 monoalkyl nitrile substituted reactant (1), which constitute the tricyclic framework of carbazole derivatives along with the substructure of the Strychnos alkaloids family, have been synthesized by using different ... -
Cr(VI) adsorption on binary and ternary composites of raw cocoa shell with magnetic nanoparticle and Prussian blue
(Elsevier B.V., 2022)Binary and ternary composites of raw cocoa shell (CS) were investigated as novel adsorbents for chromate (Cr(VI)) ions adsorption. CS incorporated with magnetite nanoparticle (MNP) and MNP-Prussian blue (MNP-PB) composites ... -
Synthesis and molecular docking study of novel COVID-19 inhibitors
(TUBITAK, 2021)In 2020, the world tried to combat the corona virus (COVID-19) pandemic. A proven treatment method specific to Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is still not found. In this study, seven new ... -
Carbazole derivatives: Synthesis, spectroscopic characterization, antioxidant activity, molecular docking study, and the quantum chemical calculations
(Elsevier, 2021)A various carbazole derivativeswere synthesized for the synthesis 2,3-Dihydro-1H-carbazol-4(9H)-one O-acetyl oxime (3), ethyl 2-(2,3,4,9-tetrahydrospiro[carbazole-1,2'-[1,3]dithiolane]-2-yl)acetate (5), 2- hydroxyethyl ... -
Determination of Major, Minor, and Toxic Elements in Tropical Fruits by ICP-OES After Different Microwave Acid Digestion Methods
(Springer, 2021)Fruits contain nutrients, minerals, trace elements, vitamins, and phytochemicals that are important in terms of human health. When fruits are consumed in a balanced diet, they have a positive effect with regard to reducing ... -
(-)-Tubifolidine as strychnos indole alkaloid: Spectroscopic charactarization (FT-IR, NMR, UV-Vis), antioxidant activity, molecular docking, and DFT studies
(Elsevier, 2021)Strychnos indole alkaloids, which include tubifolidine (2) and are an important group of complex and interesting natural compounds as bio-actives, antioxidants as well as ABCDE ring system. Four different procedures have ... -
An Effective Approach to the Strychnos Alkaloids: Total Synthesis of Tubifolidine
(Springer, 2021)A facile total synthesis of tubifolidine has been developed, which is accomplished in an 11-step synthesis of the ABCDE pentacyclic of the strychnos alkaloids with an overall yield of 10%. The key steps are the cyclization ... -
A Novel Molecule: 1-(2,6 Dichlorobenzyl)-4-(2-(2-4-hydroxybenzylidene)hydrazinyl)pyridinium Chloride and its Interaction with DNA
(Wiley-V C H Verlag Gmbh, 2021)Herein, a novel pyridine derivative, 1-(2,6 dichlorobenzyl)-4-(2-(2-4-hydroxybenzylidene)hydrazinyl)pyridinium chloride (DHPC), was synthesized as a candidate drug molecule. Interaction of DHPC with DNA was used to explore ... -
An Improved Approach to the Synthesis of (+/-)-Noruleine
(Taylor & Francis Inc, 2021)[No Abstract Available] -
A new reagent for efficient synthesis of nitriles from aldoximes using methoxymethyl bromide
(Editura Academiei Romane, 2021)This study outlines an efficient, high-yielding, and rapid method by which to access diverse nitriles from aldoximes with methoxymethyl bromide (MOM-Br) in THF. It represents the first application of MOM-Br as a deoximation ... -
New route for synthesis of 2-(2,2-dimethoxyethyl)-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b] indole and DFT investigation
(Elsevier Sci Ltd, 2020)Development of efficient sequences for the synthesis of the title compound (2-(2,2-dimethoxyethyl)-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b]indole) (7) was described. The title compound was synthesized through several ... -
The electronic and spectroscopic investigation of ( +/- )- Dasycarpidone
(Elsevier, 2020)(+/-)-Dasycarpidone ((1R,5S)-12-ethyl-2-methyl-1,2,3,4,5,7-hexahydro-6H-1,5-methanoazocino[4,3-b]indol-6one) was investigated by using the quantum chemical calculations. All DFT-based analyses were performed by B3LYP, ... -
Synthesis, characterization, UV-Vis absorption and cholinesterase inhibition properties of bis-indolyl imine ligand systems
(Elsevier, 2020)A number of bis-indolyl imine helical structures has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole with different o-phenyl diamines as pi-spacer ... -
Synthesis of Methylene Bridged Bis-pyrrolo[3,2-c]carbazoles via an Unusual Vilsmeier-Haack Product of N-Ethylcarbazole
(Taylor & Francis Ltd, 2020)The unexpected result for the formylation of N-ethylcarbazole under the Vilsmeier-Haack conditions (POCl3/DMF) led to the synthesis of novel methylene bridged bis-pyrrolo[3,2-c]carbazoles via Hemetsberger indole synthesis ... -
Glutathione-responsive multifunctionalizable hydrogels via amine-epoxy "click" chemistry
(Elsevier Ltd, 2020)A novel glutathione-responsive hydrogel was synthesized through catalyst-free epoxy-amine ‘click’ chemistry using PEG-diamine and a redox-responsive diepoxy crosslinker. The chain length of PEG-diamine component was varied ... -
In silico, 6lu7 protein inhibition using dihydroxy-3-phenyl coumarin derivatives for SARS-CoV-2
(Turkish Chemical Society, 2020)The new emerging coronavirus (SARS-CoV-2) has become a global health problem with very rapid transmission from person to person, causing severe acute respiratory problems. In the circumstance, the discovery of vaccines or ...
