Kurum Yazarı "Gürel, Ahmet" WoS İndeksli Yayınlar Koleksiyonu İçin Listeleme
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Anti-Apoptotic and Anti-Oxidant Effects of Caffeic Acid Phenethyl Ester on Cadmium-Induced Testicular Toxicity in Rats
Erboğa, Mustafa; Kanter, Mehmet; Aktaş, Cevat; Dönmez, Yeliz Bozdemir; Erboğa, Zeynep Fidanol; Aktaş, Emel; Gürel, Ahmet (Humana Press Inc, 2016)Cadmium (Cd) is a serious environmental and occupational contaminant and may represent a serious health hazard to humans and other animals. Cd is reported to induce the generation of reactive oxygen species, and induces ... -
Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with COPD
Aydın, Murat; Altıntaş, Nejat; Mutlu, Levent Cem; Bilir, Bülent; Oran, Mustafa; Tülübaş, Feti; Gürel, Ahmet (Wiley, 2017)IntroductionAsymmetric dimethylarginine (ADMA) and nitric oxide (NO) show their mechanism of action reciprocally, the balance between these molecules contributes to the tight regulation of airways tone and function. ... -
The effect of obesity and dietary habits on mean platelet volume and other platelet indices
Aydın, Murat; Nalbanto?lu, Burçin; Donma, Mustafa Metin; Tülübaş, Feti; Küçükyalçın, Volkan; Karasu, Erkut; Gürel, Ahmet (Georg Thieme Verlag Kg, 2014)In this study, the mean platelet volume (MPV) and platelet distribution width (PDW) parameters in obese children and the control group were compared with the amount of fast food consumed in the diet to determine whether ... -
The Effects of Ferulic Acid Against Oxidative Stress and Inflammation in Formaldehyde-Induced Hepatotoxicity
Gerin, Fethullah; Erman, Hayriye; Erboğa, Mustafa; Şener, Ümit; Yılmaz, Ahsen; Seyhan, Hatice; Gürel, Ahmet (Springer/Plenum Publishers, 2016)This study was designed to elucidate the protective effects of ferulic acid (FA) on formaldehyde-induced hepatotoxicity by measuring some routine biochemical parameters, cytokine levels, and oxidative stress-related ... -
The Effects of Quercetin on Acute Lung Injury and Biomarkers of Inflammation and Oxidative Stress in the Rat Model of Sepsis
Gerin, Fethullah; Şener, Ümit; Erman, Hayriye; Yılmaz, Ahsen; Aydın, Bayram; Armutcu, Ferah; Gürel, Ahmet (Springer/Plenum Publishers, 2016)Experimental studies indicate that sepsis causes remote organ injury although the molecular mechanism has not been clearly defined. In this report, the role of oxidative damage, and inflammation on lung injury, following ... -
Evaluation of Paraoxonase and Arylesterase activities in patients with irritable bowel syndrome
Oran, Mustafa; Tülübaş, Feti; Mete, Rafet; Aydın, Murat; Sarıkaya, Hatice Gul; Gürel, Ahmet (Pakistan Medical Assoc, 2014)The aims of the present study were to evaluate oxidative status, by investigating the serum Paraoxonase/Arylesterase (PON/ARE) activities along with conjugated dienes in patients with IBS and controls and to confirm the ... -
Evaluation of the Prevalence of Thyroid Autoantibodies in Patients with Alopecia Areata
Gerin, Fethullah; Albayrak, Hülya; Soydan, Zekeriya; Şener, Ümit; Yanık, Mehmet Emin; Erboğa, Mustafa; Gürel, Ahmet (Wiley-Blackwell, 2016)[No Abstract Available] -
Growth Differentiation Factor-15 Is a Novel Biomarker Predicting Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Mutlu, Levent Cem; Altıntaş, Nejat; Aydın, Murat; Tülübaş, Feti; Oran, Mustafa; Küçükyalçın, Volkan; Kaplan, Gizem; Gürel, Ahmet (Springer/Plenum Publishers, 2015)Exacerbations in chronic obstructive pulmonary disease (COPD) reduce quality of life and are associated with a more rapid deterioration of the disease. Growth differentiation factor-15 (GDF-15) is a novel candidate ... -
Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome
Tülübaş, Feti; Oran, Mustafa; Mete, Rafet; Turan, Filiz; Yılmaz, Ahsen; Yıldız, Zeynep Deniz; Gürel, Ahmet (Tubitak Scientific & Technical Research Council Turkey, 2014)Aim: Irritable bowel syndrome (IBS), a functional disorder of the bowel, has been thought to result from immune activation. The aim of this study was to evaluate macrophage migration inhibitory factor (MMIF) and monocyte ... -
Iron Deficiency Anaemia is Associated with Decreased Levels of Macrophage Migration Inhibitory Factor and Monocyte Chemoattractant Protein-1
Oran, Mustafa; Tülübaş, Feti; Mete, Rafet; Aydın, Murat; Yıldız, Zeynep Deniz; Yılmaz, Ahsen; Gürel, Ahmet (Modestum Ltd, 2015)Many bodily systems are affected by iron deficiency anaemia (IDA), including the immune system. However, the pathophysiological mechanisms whereby this anaemia promotes deterioration in immunity remain largely unexplained. ... -
MCV and MCH Values in Coronary Artery Patients with Positive Gensini Score
Tülübaş, Feti; Gürel, Ahmet; Akkoyun, Dursun Çayan; Alpsoy, Şeref; Akyüz, Aydın; Erdoğan, Hasan; Yılmaz, Ahsen (Modestum Ltd, 2013)This study aims to research whether gensini scoring of white blood cells and their subgroups and hemoglobin (Hb), hematocrit (Htc), erythroscyte and their computational tests are related, through retrospectively evaluating ... -
Neutrophil/lymphocyte ratio in obese adolescents
Aydın, Murat; Yılmaz, Ahsen; Donma, Mustafa Metin; Tülübaş, Feti; Demirkol, Muhammed; Erdoğan, Murat; Gürel, Ahmet (Kare Publ, 2015)OBJECTIVE: Obesity is a growing health problem in most of the developed countries. It is associated with many chronic diseases, affecting particularly endocrine and cardiovascular systems. Inflammation plays a key role in ... -
Plasma urotensin II and neurokinin B levels in acute myocardial infarction and stable coronary artery disease
Akkoyun, Dursun Çayan; Akyüz, Aydın; Alpsoy, Şeref; Gürel, Ahmet; Güler, Niyazi; Değirmenci, Hasan; Gurkan, Umit (Turkish Soc Cardiology, 2015)Objective: This aim of the study is to investigate whether there are possible plasma urotensin-II (U-II) and neurokinin B (NKB) level changes in patients with acute myocardial infarction (AMI) or not and plasma urotensin-II ... -
Possible association between vitamin D deficiency and restless legs syndrome
Oran, Mustafa; Ünsal, Cüneyt; Albayrak, Yakup; Tülübaş, Feti; Oğuz, Keriman; Avcı, Okan; Gürel, Ahmet (Dove Medical Press Ltd, 2014)Background and aim: Restless legs syndrome (RLS) is a distressing sleep disorder that occurs worldwide. Although there have been recent developments in understanding the -pathophysiology of RLS, the exact mechanism of the ... -
Protective Effect of Infliximab, a Tumor Necrosis Factor-Alfa Inhibitor, on Bleomycin-Induced Lung Fibrosis in Rats
Altıntaş, Nejat; Erboğa, Mustafa; Aktaş, Cevat; Bilir, Bülent; Aydın, Murat; Şengül, Aysun; Gürel, Ahmet; Topçu, Birol (Springer/Plenum Publishers, 2016)We aimed to investigate the preventive effect of Infliximab (IFX), a tumor necrosis factor (TNF)-alpha inhibitor, on bleomycin (BLC)-induced lung fibrosis in rats. Rats were assigned into four groups as follows: I-BLC ... -
Protective Effects of Curcumin against Formaldehyde-Induced Renal Toxicity in Rats (Meeting Abstract)
Şener, Ümit; Uygur, Ramazan; Kurt, Ömer; Çağlar, Veli; Gelincik, İbrahim; Gürel, Ahmet; Erdoğan, Hasan (Wiley-Blackwell, 2015)[No Abstract Available] -
The protective effects of omega-3 fatty acids on doxorubicin-induced hepatotoxicity and nephrotoxicity in rats
Tülübaş, Feti; Gürel, Ahmet; Oran, Mustafa; Topçu, Birol; Çağlar, Veli; Uygur, Emine (Sage Publications Inc, 2015)This study aims to evaluate the protective effects of omega-3 fatty acids (FAs) on doxorubicin (DOX)-induced hepatotoxicity and nephrotoxicity in rats. A total of 24 adult male Sprague Dawley rats were divided into three ... -
Purine Catabolic Enzymes and Nitric Oxide in Patients with Iron Deficiency Anemia
Oran, Mustafa; Aydın, Murat; Mete, Rafet; Tülübaş, Feti; Avcı, Okan; Yılmaz, Ahsen; Gürel, Ahmet (Carbone Editore, 2014)Introduction: To clarify the mechanism of oxidative damage,which affects many tissues and organ systems in iron deficiency anemia, comes into prominence in the treatment and avoiding the complications of the disease. In ... -
Quercetin ameliorates methotrexate-induced renal damage, apoptosis and oxidative stress in rats
Erboğa, Mustafa; Aktaş, Cevat; Erboğa, Zeynep Fidanol; Dönmez, Yeliz Bozdemir; Gürel, Ahmet (Taylor & Francis Ltd, 2015)Background: In the present study, the protective and therapeutic effects of quercetin (QE) on renal injury induced by methotrexate (MTX) have been examined. Materials and methods: A total of 24 male rats were divided into ... -
Quercetin Inhibits Heart Injury in Lipopolysaccharide-induced Endotoxemic Model by Suppressing the Effects of Reactive Oxygen Species
Akkoyun, Dursun Çayan; Akyüz, Aydın; Doğan, Mustafa; Erboğa, Mustafa; Aktaş, Cevat; Çağlar, Veli; Gürel, Ahmet (Sci Printers & Publ Inc, 2016)OBJECTIVE: To examine the histopathological and biochemical effects of quercetin (QE), which has antioxidant properties, on damaged heart muscle in a lipopolysaccharide (LPS)-induced endotoxemia model in rats. STUDY DESIGN: ...