Güncel Gönderiler: Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed
Toplam kayıt 7740, listelenen: 4561-4580
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(-)-Tubifolidine as strychnos indole alkaloid: Spectroscopic charactarization (FT-IR, NMR, UV-Vis), antioxidant activity, molecular docking, and DFT studies
(Elsevier, 2021)Strychnos indole alkaloids, which include tubifolidine (2) and are an important group of complex and interesting natural compounds as bio-actives, antioxidants as well as ABCDE ring system. Four different procedures have ... -
An Effective Approach to the Strychnos Alkaloids: Total Synthesis of Tubifolidine
(Springer, 2021)A facile total synthesis of tubifolidine has been developed, which is accomplished in an 11-step synthesis of the ABCDE pentacyclic of the strychnos alkaloids with an overall yield of 10%. The key steps are the cyclization ... -
A Novel Molecule: 1-(2,6 Dichlorobenzyl)-4-(2-(2-4-hydroxybenzylidene)hydrazinyl)pyridinium Chloride and its Interaction with DNA
(Wiley-V C H Verlag Gmbh, 2021)Herein, a novel pyridine derivative, 1-(2,6 dichlorobenzyl)-4-(2-(2-4-hydroxybenzylidene)hydrazinyl)pyridinium chloride (DHPC), was synthesized as a candidate drug molecule. Interaction of DHPC with DNA was used to explore ... -
An Improved Approach to the Synthesis of (+/-)-Noruleine
(Taylor & Francis Inc, 2021)[No Abstract Available] -
A new reagent for efficient synthesis of nitriles from aldoximes using methoxymethyl bromide
(Editura Academiei Romane, 2021)This study outlines an efficient, high-yielding, and rapid method by which to access diverse nitriles from aldoximes with methoxymethyl bromide (MOM-Br) in THF. It represents the first application of MOM-Br as a deoximation ... -
New route for synthesis of 2-(2,2-dimethoxyethyl)-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b] indole and DFT investigation
(Elsevier Sci Ltd, 2020)Development of efficient sequences for the synthesis of the title compound (2-(2,2-dimethoxyethyl)-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b]indole) (7) was described. The title compound was synthesized through several ... -
The electronic and spectroscopic investigation of ( +/- )- Dasycarpidone
(Elsevier, 2020)(+/-)-Dasycarpidone ((1R,5S)-12-ethyl-2-methyl-1,2,3,4,5,7-hexahydro-6H-1,5-methanoazocino[4,3-b]indol-6one) was investigated by using the quantum chemical calculations. All DFT-based analyses were performed by B3LYP, ... -
Synthesis, characterization, UV-Vis absorption and cholinesterase inhibition properties of bis-indolyl imine ligand systems
(Elsevier, 2020)A number of bis-indolyl imine helical structures has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole with different o-phenyl diamines as pi-spacer ... -
Synthesis of Methylene Bridged Bis-pyrrolo[3,2-c]carbazoles via an Unusual Vilsmeier-Haack Product of N-Ethylcarbazole
(Taylor & Francis Ltd, 2020)The unexpected result for the formylation of N-ethylcarbazole under the Vilsmeier-Haack conditions (POCl3/DMF) led to the synthesis of novel methylene bridged bis-pyrrolo[3,2-c]carbazoles via Hemetsberger indole synthesis ... -
Glutathione-responsive multifunctionalizable hydrogels via amine-epoxy "click" chemistry
(Elsevier Ltd, 2020)A novel glutathione-responsive hydrogel was synthesized through catalyst-free epoxy-amine ‘click’ chemistry using PEG-diamine and a redox-responsive diepoxy crosslinker. The chain length of PEG-diamine component was varied ... -
In silico, 6lu7 protein inhibition using dihydroxy-3-phenyl coumarin derivatives for SARS-CoV-2
(Turkish Chemical Society, 2020)The new emerging coronavirus (SARS-CoV-2) has become a global health problem with very rapid transmission from person to person, causing severe acute respiratory problems. In the circumstance, the discovery of vaccines or ... -
Magnetite nanoparticles-based hydroxyl radical scavenging activity assay of antioxidants using N, N-dimethyl-p-phenylenediamine probe
(TUBITAK, 2020)Excessive amounts of reactive oxygen species (ROS), unless counterbalanced by antioxidants, can cause cellular damage under oxidative stress conditions; therefore, antioxidative defenses against ROS must be measured. With ... -
Novel pathway for the synthesis of 20-deethyltubifolidine
(Syscom 18 SRL, 2020)A new and well planned approach has been accomplished for the total synthesis of 20-Deethyltubifolidine, which is effective for biological properties and fascinating molecules. This product embodies the ABCDE-ring system ... -
The synthesis of rGO, rGO/RuO2 and rGO/RuO2/PVK nanocomposites, and their supercapacitors
(Elsevier Science Sa, 2019)In this study, graphene oxide (GO) was eco-friendly and reduced with microwave-assisted method to form reduced graphene oxide (rGO). Two components of nanocomposite of rGO and Ruthenium oxide (RuO2) (rGO/RuO2) and a ternary ... -
Determination of Trace and Major Elements in Vegan Milk and Oils by ICP-OES After Microwave Digestion
(Humana Press Inc, 2020)Increasing technological developments also bring about environmental pollution. Heavy metals and metallic compounds, as a result of soil, water, and air industrialization, pass through to people and animals through the ... -
Synthesis, photophysical and antioxidant properties of carbazole-based bis-thiosemicarbazones
(Springer, 2019)Utilizing Schiff base condensation of the 9-ethylcarbazole-3,6-dicarbaldehyde and thiosemicarbazides, four new N-ethylcarbazole-based bis-thiosemicarbazone compounds 4a-d were successfully synthesized in high yields. The ... -
Synthesis, photophysical and antioxidant properties of pyrrolo[3,2-c]carbazole and dipyrrolo[3,2-c:2,3-g]carbazole compounds
(Springer, 2019)The synthesis of (6-ethyl-1,6-dihydropyrrolo[3,2-c]carbazol-2-yl)methanol 5 and (6-ethyl-6,11-dihydro-1H-dipyrrolo[3,2-c:2,3-g]carbazole-2,10-diyl)dimethanol 6 were achieved via the reduction of methyl pyrrolo carbazole ... -
An Efficient Synthesis of Nitriles from Aldoximes in the Presence of Trifluoromethanesulfonic Anhydride in Mild Conditions
(Maik Nauka/Interperiodica/Springer, 2020)A new and convenient protocol has been proposed for the transformation of aldoximes to nitriles using trifluoromethanesulfonic anhydride and triethylamine. The proposed method allows a range of aldoximes, including aromatic, ... -
A New Approach to the Total Synthesis of 20-Deethyltubifolidine and an Entry to the Azocino[4,3-b]indoles
(Taylor & Francis Inc, 2020)[No Abstract Available] -
A Facile and Convenient Synthesis of (+/-)-Dasycarpidone
(Springer, 2020)An efficient new pathway for (+/-)-dasycarpidone has been synthesized. The most important step in the synthesis of (+/-)-dasycarpidone is the intramolecular cyclization of the azocino[4,3-b]indole skeleton, which is ...