Güncel Gönderiler: Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed
Toplam kayıt 7740, listelenen: 2721-2740
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Üç Boyutlu Hücre Kültürü Sistemlerine Güncel Yaklaşımlar
(2020)İki boyutlu (2B) hücre kültürü, hücre temelli araştırmalar için değerli bir yöntemdir ancak in vivo yanıtlar hakkında öngörülemeyen, yanıltıcı veriler sağlayabilir. Son yirmi yılda, hücresel mikro çevrenin (örneğin hücre ... -
Protective effects of quercetin on testicular torsion/detorsion-induced ischaemia-reperfusion injury in rats
(Wiley-Blackwell, 2010)P>The aim of this study was to investigate the protective effect of quercetin (QE) on testicular torsion/detorsion-induced ischaemia-reperfusion (I/R) injury. A total of 24 male Wistar albino rats were divided into three ... -
Protective effects of irbesartan and alpha lipoic acid in STZ-induced diabetic nephropathy in rats
(Taylor & Francis Ltd, 2010)The aim of this study was designed to investigate the possible beneficial effects of the angiotensin (ang) II T-1 (AT(1)) receptor blocker, irbesartan (Irb), and the alpha lipoic acid (ALA) in streptozotocin (STZ)-induced ... -
Effects of experimental diabetes on testis proliferations and apoptosis in rats
(2011)This work aimed to investigate the role of diabetes on cell proliferation, and apoptosis in testis. The rats were randomly allotted into one of two experimental groups: control and diabetic group; each group contain 10 ... -
The protective effects of endothelin-A receptor antagonist BQ-123 in pentylenetetrazole-induced seizure in rats
(Sage Publications Ltd, 2014)Endothelin-1 has been shown to increase neuronal activity and glutaminergic synaptic transmission by endothelin-A receptors (ETAR) in the nucleus tractus solitarius neurons that play an important role in epileptic seizures. ... -
Beneficial effects of melatonin and BQ-123 on the rat testis damage caused by cigarette smoke
(Tubitak Scientific & Technical Research Council Turkey, 2015)Background/aim: Several studies have demonstrated that cigarette smoke has detrimental effects on testicular function. However, it is unknown whether melatonin or BQ-123 has beneficial effects on the rat testis damage ... -
Could Mean Platelet Volume Be Used as A Marker for Oral Aphthae and Activity of Behcet's Disease?
(Aves, 2016)Objective: Behcet's disease is a common inflammatory disease in our country. We aimed to determine whether mean platelet volume can be used as a marker for oral aphthae and the activity of Behcet's disease, Methods: Between ... -
Angiotensin II receptor blockade - Importance for intestinal smooth muscle tone
(Publ House Bulgarian Acad Sci, 2015)The significance of AT(1) and AT(2) receptor subtypes for the development of Angiotensin II (Ang II)-induced contractions of different intestinal segments was investigated. Longitudinal strips from rat jejunum, ileum, colon ... -
Neuroprotective Effect of Thymoquinone through miR-204-3p in 6-Hydroxydopamine-Induced Parkinson Model
(Wiley, 2018)[No Abstract Available] -
Association analyses of oxidative stress, aerobic capacity, daily physical activity, and body composition parameters in patients with mild to moderate COPD
(Tubitak Scientific & Technical Research Council Turkey, 2014)Background/aim: To investigate total oxidant and antioxidant status, maximal aerobic capacity, daily physical activity, pulmonary functions, and body composition changes, as well as the associations among these parameters, ... -
Measurement of hydroxyproline and nitric oxide, and comparison of sac fluid acidity in different inguinal pathologies
(Elsevier Sci Ltd, 2013)Purpose: To compare hydroxyproline and nitric oxide levels, and fluid acidity between sac tissues from inguinal hernia, hydrocele and undescended testis patients. Material and method: Thirty patients were in the inguinal ... -
Thyroid Dysfunctions Due to Lithium Treatment in Bipolar Disorder: Changes in Oxidative Stress, Trace Elements, and Hemorheological Parameters
(Polish Society Magnesium Research, 2020)Lithium is one of the most widely used medications for the treatment of bipolar disorder (BD). It also has some side effects on thyroid functions. We aimed to investigate the role of oxidative stress, trace elements, and ... -
Ortalama Trombosit Hacmi Behçet Hastalarında Oral Aft ve Hastalık Aktivite Belirteci Olarak Kullanılabilir mi?
(2016)Amaç: Çalışmamızda; ülkemizde sık görülen inflamatuvar bir hastalık olan Behçet hastalarının ortalama trombosit hacmi değerlerinin, hastalarda görü- len oral aft varlığının ve hastalık aktivitesinin belirteci olarak ... -
Relationship between the infarct localization and left ventricular rotation parameters following acute ST-segment elevation myocardial infarction
(Turkish Soc Cardiology, 2020)Ojective: This study was an investigation of the role of left ventricular (LV) apical rotation seen in the early period after myocardial infarction (MI) in predicting infarct localization. Methods: A total of 124 patients ... -
LOX-1 gene variants and maternal levels of plasma oxidized LDL and malondialdehyde in patients with gestational diabetes mellitus
(Springer Heidelberg, 2016)Purpose The aim of this study was to investigate the relationships between the maternal levels of oxidized LDL (ox-LDL), lipid peroxidation marker malondialdehyde (MDA) and LOX-1 3'UTR188C/T and K167N single nucleotide ... -
The Circulating Levels of Selenium, Zinc, Midkine, Some Inflammatory Cytokines, and Angiogenic Factors in Mitral Chordae Tendineae Rupture
(Humana Press Inc, 2015)Chordae tendineae rupture process is associated with increased production of inflammatory and angiogenesis mediators in connective tissues, which contributes to chronic inflammation and pathogenesis of degenerative chordae. ... -
Serum paraoxonase (a high-density lipoprotein-associated lipophilic antioxidant) activity in clinical follow-up of patients with acute pancreatitis, with particular emphasis on oxidative stress parameters and lipid profile: a prospective pilot trial
(Taylor & Francis Ltd, 2019)The purpose of this study was to investigate the possible role of PON-1, an antioxidant lipophilic enzyme linked to HDL-C (high-density lipoprotein cholesterol), on the pathophysiology and clinical follow-up of acute ... -
Clinical usefulness of red cell distribution width to angiographic severity and coronary stent thrombosis
(Dove Medical Press Ltd, 2016)Background: Red cell distribution width (RDW) is a quantitative measurement and shows heterogeneity of red blood cell size in peripheral blood. RDW has recently been associated with cardiovascular events and cardiovascular ... -
Evaluation of metallothionein-1, metallothionein-2, lipid peroxidation and trace elements status in the progression of the spontaneous mitral chordae tendineae rupture patients
(Dustri-Verlag Dr Karl Feistle, 2016)Objective: The aim of the present study was to investigate whether copper, zinc and iron levels and copper/zinc, iron/zinc, iron/copper ratios in serum and erythrocytes are associated with lipid oxidation levels, ... -
Paraoxonase and Arylesterase Activities, Lipid Profile, and Oxidative Damage in Experimental Ischemic Colitis Model
(Hindawi Ltd, 2012)Objective. In the present study, since PON1 is known as an HDL-associated antioxidant enzyme that inhibits the oxidative modification of LDL and oxidative stress plays a role in the pathogenesis of mesenteric ischemia, we ...