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Toplam kayıt 85, listelenen: 41-50
An efficient studies on C-2 cyanomethylation of the indole synthesis: the electronic and spectroscopic characterization (FT-IR, NMR, UV-Vis), antioxidant activity, and theoretical calculations
(Elsevier, 2022)
The direct cynamethylation with the development of catalyzed methodologies directed to 2-(cyanomethyl)indoles was reported by using tetrafluoro-1,4-benzoquinone (TFB) as the catalyst and it was synthesized in one step ...
Forced Degradation Studies of Nateglinide by the First-Order Derivative Spectrophotometric Method and the Density Functional Theory of the Nateglinide Molecule
(Springer, 2022)
Nateglinide (NAT) is an oral antihyperglycemic agent used for the treatment of noninsulin-dependent diabetes mellitus. We evaluated the NAT stability under various forced degradation tests (acidic, basic) and predicted the ...
Cyanomethylation of 2,3,4,9-tetrahydro-1H-carbazol-1-one based on using two different reagents: Antioxidant activity and DFT studies
(Elsevier, 2022)
C-2 and C-6 monoalkyl nitrile substituted reactant (1), which constitute the tricyclic framework of carbazole derivatives along with the substructure of the Strychnos alkaloids family, have been synthesized by using different ...
New route for synthesis of 2-(2,2-dimethoxyethyl)-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b] indole and DFT investigation
(Elsevier Sci Ltd, 2020)
Development of efficient sequences for the synthesis of the title compound (2-(2,2-dimethoxyethyl)-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b]indole) (7) was described. The title compound was synthesized through several ...
The electronic and spectroscopic investigation of ( +/- )- Dasycarpidone
(Elsevier, 2020)
(+/-)-Dasycarpidone ((1R,5S)-12-ethyl-2-methyl-1,2,3,4,5,7-hexahydro-6H-1,5-methanoazocino[4,3-b]indol-6one) was investigated by using the quantum chemical calculations. All DFT-based analyses were performed by B3LYP, ...
Synthesis, characterization, UV-Vis absorption and cholinesterase inhibition properties of bis-indolyl imine ligand systems
(Elsevier, 2020)
A number of bis-indolyl imine helical structures has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole with different o-phenyl diamines as pi-spacer ...
Electrochemical Characteristics of a Novel Pyridinium Salt as a Candidate Drug Molecule and Its Interaction with DNA
(Wiley-V C H Verlag Gmbh, 2020)
In this article, for the first time, the electrochemical properties of a novel pyridine derivative, 4-(2-(2-hydroxybenzylidene) hydrazinyl)-1-(3-phenylpropyl) pyridinium bromide (abbreviated as 4-Pyri), and its interaction ...
Synthesis of Methylene Bridged Bis-pyrrolo[3,2-c]carbazoles via an Unusual Vilsmeier-Haack Product of N-Ethylcarbazole
(Taylor & Francis Ltd, 2020)
The unexpected result for the formylation of N-ethylcarbazole under the Vilsmeier-Haack conditions (POCl3/DMF) led to the synthesis of novel methylene bridged bis-pyrrolo[3,2-c]carbazoles via Hemetsberger indole synthesis ...
Theoretical and experimental photodegradation of Phosmet via oxidation techniques in the presence of aqueous TiO2suspension
(Bulgarska Akademiya na Naukite, 2021)
This study is conducted with the aim to analyze the reaction kinetics of Phosmet with the OH radical, and to determine its mechanism. Due to the lack of experimental evidence of radical intermediate products occurring ...
Glutathione-responsive multifunctionalizable hydrogels via amine-epoxy "click" chemistry
(Elsevier Ltd, 2020)
A novel glutathione-responsive hydrogel was synthesized through catalyst-free epoxy-amine ‘click’ chemistry using PEG-diamine and a redox-responsive diepoxy crosslinker. The chain length of PEG-diamine component was varied ...