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Toplam kayıt 20, listelenen: 1-10
Magnetite nanoparticles-based hydroxyl radical scavenging activity assay of antioxidants using N, N-dimethyl-p-phenylenediamine probe
(Scientific Technical Research Council Turkey-Tubitak, 2020)
Excessive amounts of reactive oxygen species (ROS), unless counterbalanced by antioxidants, can cause cellular damage under oxidative stress conditions; therefore, antioxidative defenses against ROS must be measured. With ...
A new approach to the total synthesis of (±)-nordasycarpidone by ring-closure with tetrachloro-1,4-benzoquinone
(Macedonian Journal of Chemistry and Chemical Engineering, 2020)
new synthetic route for the (±)-nordasycarpidone was achieved in five steps with an overall yield of 41 %. This route involves ring closure and formation of 5 which has a methanoazocino[4,3-b]indole skeleton in the key ...
Target-Driven Design of a Coumarinyl Chalcone Scaffold Based Novel EF2 Kinase Inhibitor Suppresses Breast Cancer Growth in Vivo
(American Chemical Society, 2021)
Eukaryotic elongation factor 2 kinase (eEF-2K) is an unusual alpha kinase involved in protein synthesis through phosphorylation of elongation factor 2 (EF2). eEF-2K is highly overexpressed in breast cancer, and its activity ...
Supercapacitor performances of titanium-polymeric nanocomposites: a review study
(Springer Science and Business Media Deutschland GmbH, 2022)
This review article presents a research and technological investigation on supercapacitors and describes the recent advances of titanium-based materials in these areas. The introduction covers the properties of titanium ...
Design and in silico study of the novel coumarin derivatives against SARS-CoV-2 main enzymes
(Taylor and Francis Ltd., 2020)
The novel coronavirus (SARS-CoV-2) causes severe acute respiratory syndrome and can be fatal. In particular, antiviral drugs that are currently available to treat infection in the respiratory tract have been experienced, ...
Synthesis and molecular docking study of novel COVID-19 inhibitors
(Scientific Technical Research Council Turkey-Tubitak, 2021)
In 2020, the world tried to combat the corona virus (COVID-19) pandemic. A proven treatment method specific to Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is still not found. In this study, seven new ...
Photodegradation kinetics of organophosphorous with hydroxyl radicals: Experimental and theoretical study
(Serbian Chemical Society, 2021)
The presence of organophosphorus compounds (OPs) in the environmental counterparts has become an important problem because of their toxicity. In this study, the photocatalytic degradation reactions of the three OPs with ...
New route for synthesis of 2-(2,2-dimethoxyethyl)-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b] indole and DFT investigation
(Elsevier Sci Ltd, 2020)
Development of efficient sequences for the synthesis of the title compound (2-(2,2-dimethoxyethyl)-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b]indole) (7) was described. The title compound was synthesized through several ...
In silico, 6lu7 protein inhibition using dihydroxy-3-phenyl coumarin derivatives for SARS-CoV-2
(Turkish Chemical Society, 2020)
The new emerging coronavirus (SARS-CoV-2) has become a global health problem with very rapid transmission from person to person, causing severe acute respiratory problems. In the circumstance, the discovery of vaccines or ...
A new reagent for efficient synthesis of nitriles from aldoximes using methoxymethyl bromide
(Editura Academiei Romane, 2021)
This study outlines an efficient, high-yielding, and rapid method by which to access diverse nitriles from aldoximes with methoxymethyl bromide (MOM-Br) in THF. It represents the first application of MOM-Br as a deoximation ...