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Toplam kayıt 62, listelenen: 11-20
The role of primary tumor resection in patients with stage IV colorectal cancer with unresectable metastases
(Zerbinis Publications, 2020)
Purpose: Whether primary tumor resection (PTR) should be performed in patients with asymptomatic colorectal cancer (CRC) and unresectable synchronous metastasis is controversial. The purpose of this study was to investigate ...
PD-1 and PD-L2 expression predict relapse risk and poor survival in patients with stage III colorectal cancer
(Springer Science and Business Media B.V., 2021)
Background: Immune responses have long been an area of interest in cancer research. In this study, the effects of programmed cell death-1 (PD-1) and its ligand (PD-L2) on the prognosis of colorectal cancer (CRC) were ...
Relationship between pruritus and autotaxin in intrahepatic cholestasis of pregnancy
(Ediciones Doyma, S.L., 2021)
Objective: Intrahepatic cholestasis of pregnancy is a temporary, pregnancy-specific disease that resolves with delivery, characterized by itching (pruritus), as well as high transaminase and serum bile acid levels in the ...
Increased serum BDNF and ProBDNF levels in children with irritable bowel syndrome
(Elsevier Inc., 2020)
Objective: Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders among the pediatric population. Recently, neurotrophins have been suggested to be etiological factors or causes of ...
Hypoplastic internal carotid artery ending as an ophthalmic artery with multiple cerebral aneurysms, fenestrated Acom and triple A2
(BMJ Publishing Group, 2021)
A rare case of a hypoplastic internal carotid artery (ICA) terminating in the ophthalmic artery with multiple intracranial saccular aneurysms in the contralateral ICA, anterior communicating artery fenestration and triple ...
The role of oxidized phospholipids in COVID-19-associated hypercoagulopathy
(Verduci Editore s.r.l, 2021)
OBJECTIVE: There is more pronounced hypercoagulation in COVID-19 infection than in other viral lung infections. Oxidized phospholipids (OxPLs) appear in COVID-19-infected lungs due to oxidative stress, after which they ...
Psychophysical detection and learning in freely behaving rats: a probabilistic dynamical model for operant conditioning
(Springer, 2020)
We present a stochastic learning model that combines the essential elements of Hebbian and Rescorla-Wagner theories for operant conditioning. The model was used to predict the behavioral data of rats performing a vibrotactile ...
Identifying Clinical Characteristics of Hypoparathyroidism in Turkey: HIPOPARATURK-NET Study
(Springer, 2022)
Hypoparathyroidism is an orphan disease with ill-defined epidemiology that is subject to geographic variability. We conducted this study to assess the demographics, etiologic distribution, treatment patterns and complication ...
The Real-World Experience With Single Agent Ibrutinib in Relapsed/Refractory CLL
(Elsevier Inc., 2022)
Introduction/Background: The emergence of novel agents targeting the B-cell receptor pathway and BCL-2 has significantly changed the therapeutic landscape of CLL. We evaluated the safety and efficacy of single-agent ibrutinib ...
Novel inhibitors of eukaryotic elongation factor 2 kinase: in silico, synthesis and in vitro studies
(Academic Press Inc., 2021)
Eukaryotic elongation factor 2 kinase (eEF2K) is an unusual alpha kinase whose expression is highly upregulated in various cancers and contributes to tumor growth, metastasis, and progression. More importantly, eEF2K ...