Ara
Toplam kayıt 44, listelenen: 11-20
Systematic Evaluation of Promising Clinical Trials-Gene Silencing for the Treatment of Glioblastoma
(Turkish Neurosurgical Soc, 2019)
AIM: To systematically investigate the role of artificial small interfering RNA (SiRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field ...
Does Nimodipine, a Selective Calcium Channel Blocker, Impair Chondrocyte Proliferation or Damage Extracellular Matrix Structures?
(Bentham Science Publ Ltd, 2019)
Background: The study aimed to investigate the effects of the active ingredient, nimodipine, on chondrocyte proliferation and extracellular matrix (ECM) structures in cartilage tissue cells. Methods: Chondrocyte cultures ...
A Study of the Effects of Metformin, a Biguanide Derivative, on Annulus Fibrosus and Nucleus Pulposus Cells
(Turkish Neurosurgical Soc, 2020)
AIM: To investigate the effects of metformin, a drug used widely for the treatment of type 2 diabetes mellitus, on human primary cell cultures prepared from uninjured segment of disc material intervertebral disk tissues. ...
Delivering Growth Factors through a Polymeric Scaffold to Cell Cultures Containing both Nucleus Pulposus and Annulus Fibrosus
(Turkish Neurosurgical Soc, 2019)
AIM: To design a novel, polyvinyl alcohol (PVA)-based polymeric scaffold that permits the controlled release of insulin-like growth factor 1 (IGF-1)/bone morphogenetic protein (BMP)-2 following intervertebral disc ...
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
(Spandidos Publ Ltd, 2019)
The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti-pyretic and anti-spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells in vitro. After surgical ...
Are treatment guides and rational drug use policies adequately exploited in combating respiratory system diseases?
(Elsevier Science London, 2016)
The aim of the present study was to increase awareness regarding the rational use of medicines. The data were obtained via the Material Resources Management System Module of the Ministry of Health. For the appropriateness ...
Should the cardiac rhythm be monitored following administration of zoledronic acid in elderly osteoporotic women?
(Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2016)
Objectives: This study aims to investigate the possible undesirable cardiac effects associated with zoledronic acid treatment in elderly osteoporotic women. Patients and methods: Between October 2010 and December 2013, a ...
How Different Methodologies of Harvesting and Analysing the Samples Affect the Test Results in Determining Joint Mediators
(Hindawi Ltd, 2013)
Purpose. This study has researched the affect of different methodologies of harvesting and analysing the samples in determining the mediators emerging after the rat articular cartilage injury. Materials and Methods. One ...
Does transcription factor, induced by daptomycin and vancomycin, affect HIF-1?, Chondroadherin, and COL2A1?
(2018)
Aim: In this study, it was firstly aimed to investigate the effect of Daptomycin (DAP) on the proliferation in Vancomycin (VCM)-administered primary chondrocyte cultures and non-drug-administered primary chondrocyte cultures. ...
Are biological agents toxic to human chondrocytes and osteocytes?
(Bmc, 2015)
Purpose: The aim of the present study is to investigate the effects of biological agents (BAs) on human chondrocytes and osteocytes in vitro. Methods: Primary cell cultures obtained from gonarthrosis patients were divided ...