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Toplam kayıt 13, listelenen: 1-10
Is it Possible to Treat Osteosarcoma Using Oligonucleotides Confined into Controlled Release Drug Delivery Systems?
(Bentham Science Publ Ltd, 2017)
Purpose: The present study aimed to analyze the researches that are at the experimental phase concerning osteosarcoma treatment. The researches included drug delivery systems which allow controlled release and imbue small ...
Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue
(Spandidos Publ Ltd, 2019)
The aim of the present study was to investigate the effects of etanercept (ETA), a tumor necrosis factor (TNF) inhibitor, on human cell cultures prepared from intact intervertebral disc tissue. ETA is used as a treatment ...
Systematic Evaluation of Promising Clinical Trials-Gene Silencing for the Treatment of Glioblastoma
(Turkish Neurosurgical Soc, 2019)
AIM: To systematically investigate the role of artificial small interfering RNA (SiRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field ...
Delivering Growth Factors through a Polymeric Scaffold to Cell Cultures Containing both Nucleus Pulposus and Annulus Fibrosus
(Turkish Neurosurgical Soc, 2019)
AIM: To design a novel, polyvinyl alcohol (PVA)-based polymeric scaffold that permits the controlled release of insulin-like growth factor 1 (IGF-1)/bone morphogenetic protein (BMP)-2 following intervertebral disc ...
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
(Spandidos Publ Ltd, 2019)
The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti-pyretic and anti-spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells in vitro. After surgical ...
Melatonin reverses the oxidative stress and mitochondrial dysfunction caused by LETM1 silencing
(Wiley, 2020)
LETM1 is a mitochondrial inner-membrane protein, which is encoded by a gene present in a locus of 4p, which, in turn, is deleted in the Wolf-Hirschhorn Syndrome, and is assumed to be related to its pathogenesis. The cellular ...
Hydrogen Sulphide and Nitric Oxide Cooperate in Cardioprotection Against Ischemia/Reperfusion Injury in Isolated Rat Heart
(Int Inst Anticancer Research, 2020)
Background/Aim: This study was designed to provide further evidence for the interactions between hydrogen sulfide (H2S) and nitric oxide (NO) in ischemia/reperfiision (I/R) injury. Materials and Methods: Rat hearts were ...
Transcriptome analysis of the effects of light and dark cycle on hydrogen production metabolism of Rhodobacter capsulatus DSM1710
(Pergamon-Elsevier Science Ltd, 2020)
Photosynthetic purple non sulfur bacteria can be utilized in outdoor photobioreactors for sustainable large-scale biohydrogen production. However, the diurnal cycle under natural outdoor conditions affects hydrogen ...
Donkey milk kefir induces apoptosis and suppresses proliferation of Ehrlich ascites carcinoma by decreasing iNOS in mice
(Taylor & Francis Ltd, 2018)
Donkey milk and donkey milk kefir exhibit antiproliferative, antimutagenic and antibacterial effects. We investigated the effects of donkey milk and donkey milk kefir on oxidative stress, apoptosis and proliferation in ...
Genetics and phenomics of inherited and sporadic non-autoimmune hyperthyroidism
(Elsevier Ireland Ltd, 2010)
TSH receptor (TSHR) germline mutations occur as activating mutations in familial non-autoimmune hyperthyroidism (FNAH) or sporadic non-autoimmune hyperthyroidism (SNAH). Up to date 17 constitutively activating TSHR mutations ...