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Prognostic values of various hematological variables as markers of systemic inflammation in metastatic lung cancer
(Wolters Kluwer Medknow Publications, 2020)
Background: Chronic state of inflammation is an important factor in advanced cancer which is used by tumor cells for maintaining survival and growth. Hematological parameters such as neutrophil/lymphocyte ratio (NLR), ...
The relationship of serum asymmetric dimethylarginine concentrations and lung involvement in patients with COVID-19 infection
(2021)
Aim: COVID-19 infections the tissue through angiotensin converting enzyme 2 receptor, which is also expressed on endothelial cells. Endothelial dysfunction may be associated with lung involvement. Asymmetric dimethylarginine ...
The Effects of Topiramate Applied to the Nucleus Accumbens Region on Morphine Withdrawal Syndrome
(2020)
Aim: Nucleus accumbens, one of the nuclei of the basal ganglia, and dopamine, the neurotransmitter play a critical role in opioiddependence and withdrawal. In opioid withdrawal, the importance of neurotransmitters such as ...
The Effects of L-Name and Agmatine in the Nucleus Accumbens Core Region on Morphine Withdrawal Syndrome
(2020)
Aim: The mesocorticolimbic dopaminergic system, especially the nucleus accumbens, is an important region in opioid dependence and withdrawal. Studies have shown that nitric oxide synthase inhibitors modulate the development ...
Protective Effects of Idebenone against Sepsis Induced Acute Lung Damage
(Taylor & Francis Inc, 2022)
Background/Aims Sepsis is an uncontrolled systemic infection, withcomplex pathophysiology that may result in acute lung organ damage and cause multiple organ failure. Although much research has been conducted to illuminate ...
Genetic screening results of individuals with high risk BRCA-related breast/ovarian cancer in Trakya region of Turkey
(Imprimatur Publications, 2020)
Purpose: Pathogenic/likely pathogenic (P/LP) germline variations in BRCA1 and BRCA2 genes are responsible for the majority of hereditary breast and ovarian cancers. This study presents the BRCA1/BRCA2 sequencing and deletion ...
Investigation of the Relationship Between Genome Wide Association Studies-derived Polymorphisms and Differentiated Thyroid Cancer Risk in a Turkish Population
(Gazi Univ, Fac Med, 2021)
Background: Thyroid cancer is the most common malignancy of endocrine system. Genome Wide Association Studies (GWAS) revealed a number of common variants associated with thyroid cancer risk. In this study, we aimed to ...
Breast, ovarian and other site cancer patients with BRCA 1/2 mutations: Data from Turkish multicenter retrospective study
(Zerbinis Publications, 2021)
Purpose: To demonstrate the clinical and demographic findings of the patients harboring BRCA1/2 mutations with breast, genital tract, prostate and pancreas cancers. Methods: The results of sequencing analysis of 200 cancer ...
A cadaveric study: the relationship between sternum and internal thoracic artery
(Japan International Cultural Exchange Foundation, 2021)
Introduction: Internal thoracic artery is an artery which frequently used in coronary bypass operations. Morphological features such as the location, length, and separation point of the branches are important crucialy. ...
Üç Boyutlu Hücre Kültürü Sistemlerine Güncel Yaklaşımlar
(2020)
İki boyutlu (2B) hücre kültürü, hücre temelli araştırmalar için değerli bir yöntemdir ancak in vivo yanıtlar hakkında öngörülemeyen, yanıltıcı veriler sağlayabilir. Son yirmi yılda, hücresel mikro çevrenin (örneğin hücre ...