Kurum Yazarı "Güzel, Savaş" Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed İçin Listeleme
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Investigation of Serum Folate-Receptor-1 in Patients with Non- Small Cell Lung Cancer
Çelikkol, Aliye; Seber, Erdoğan Selçuk; Güzel, Savaş; Yolcu, Ahmet; Yetişyiğit, Tarkan; Yılmaz, Ahsen (Duzce Univ, Fac Medicine, 2022)Objective: Histopathological overexpression of folate receptor-1(FOLR1) involved in folate transport in cell growth has been reported in various cancers. Increased serum FOLR1 (sFOLR1) has also been reported in epithelial ... -
Is meteorin-like (Metrnl) a novel biomarker to distinguish patients with obstructive sleep apnea (OSA) and patients with OSA at vascular risk
Altıntaş, Nejat; Fazlioğlu, Nevin; Güzel, Savaş; Yılmaz, Ahsen; Aydın, Cihan (Springer Heidelberg, 2023)PurposeMetrnl, a newly discovered adipokine with significant expression in white adipose tissue, promotes energy expenditure and contributes to the development of cardiovascular disorders. Endocan is a surrogate marker for ... -
Is subclinical hypothyroidism contributing dyslipidemia and insulin resistance in women with polycystic ovary syndrome?
Çelik, Cem; Abalı, Remzi; Taşdemir, Nicel; Güzel, Savaş; Yüksel, Aytac; Aksu, Erson; Yılmaz, Murat (Taylor & Francis Ltd, 2012)We aimed to analyze lipid parameters and determine the need for a 2-hour oral glucose tolerance test (OGTT) for the identification of IR and impaired glucose tolerance test (IGT) in subclinical hypothyroidism (SCH) women ... -
May the level and ratio changes of trace elements be utilized in identification of disease progression and grade in prostatic cancer?
Kızıler, Ali Rıza; Aydemir, Birsen; Güzel, Savaş; Alıcı, Bülent; Ataus, S.; Tuna, M. B.; Kılıç, M. (Dustri-Verlag Dr Karl Feistle, 2010)Objective: The effects of the level and ratio changes in the trace elements have been reported previously in several diseases. The aim of this study was to determine whether those trace elements (Cu, Fe and Zn) can be used ... -
Measurement of salusin-beta without the addition of NP-40 or Tween-20 in coronary slow-flow phenomenon Reply
Akyüz, Aydın; Aydın, Fatma; Alpsoy, Şeref; Özkaramanlı Gür, Demet; Güzel, Savaş (Aves, 2020)[No Abstract Available] -
Midkine Levels and its Relationship with Atherosclerotic Risk Factors in Essential Hypertensive Patients
Güzel, Savaş; Cinemre, Fatma Behice Serinkan; Güzel, Eda Çelik; Küçükyalçın, Volkan; Kızıler, Ali Rıza; Çavuşoğlu, Coşkun; Aydemir, Birsen (Wolters Kluwer Medknow Publications, 2018)Background and Objectives: Hypertension (HT) is one of the risk factors associated with atherosclerosis. Midkine (MK) plays a role as a growth factor in various biologic and pathologic events. In some reports, MK expression ... -
No Relationship Between 25 Oh Vitamin D and Autoimmunity in Women Patients with Hypothyroidism
Boyuk, Banu; Altay, Murat; Atalay, Hande; Güzel, Savaş; Çelebi, Aslan; Ekizoğlu, İsmail (Carbone Editore, 2016)Introduction: Hypothyroidism is a common disease in the society. Based on the effects of vitamin D on immune system and endocrine system, the relationship between hypothyroidism and vitamin D gained importance. The ... -
No relationship between osteoprotegerin concentrations and endothelial dysfunction in non-obese women with and without polycystic ovary syndrome
Abalı, Remzi; Taşdemir, Nicel; Alpsoy, Şeref; Taşdemir, Ufuk Göker; Güzel, Savaş; Yüksel, Mehmet Aytaç; Yılmaz, Murat (Springer Heidelberg, 2015)To investigate the relationships of osteoprotegerin (OPG) concentrations to brachial artery flow-mediated vasodilation (FMD) and the carotid artery intima media thickness (CIMT) in polycystic ovary syndrome (PCOS). ... -
Nondiyabetik obez kadınlarda hepatosteatoz ve insülin direnci arasındaki ilişki
Amaç: Bu çalışmada, normal glikoz toleranslı obez kadı n hastalarda ultrason ile saptanan karaciğer yağlanması ile insülin direnci arasındaki ilişkinin incelenmesi amaçlandı. Gereç ve Yöntemler: Çalışmaya beden kitle indeksi ... -
Novel imaging modalities in detection of cardiovascular involvement in ankylosing spondylitis
Özkaramanlı Gür, Demet; Özaltun, Derya Necmiye; Güzel, Savaş; Sarıfakıo?lu, Ayşe Banu; Akyüz, Aydın; Alpsoy, Şeref; Baykiz, Derya (Taylor & Francis Ltd, 2018)Objectives: The diagnosis of cardiovascular involvement in ankylosing spondylitis (AS) is usually delayed since conventional echocardiography relies mainly on the morphological alterations. The aim of this study was to ... -
nvestigation of Serum Folate-Receptor-1 in Patients with Non- Small Cell Lung Cancer
Şeber, Erdoğan Selçuk; Yetişyiğit, Tarkan; Yolcu, Ahmet; Çelikkol, Aliye; Güzel, Savaş; Yılmaz, Ahsen (2022)Objective: Histopathological overexpression of folate receptor-1(FOLR1) involved in folate transport in cell growth has been reported in various cancers. Increased serum FOLR1 (sFOLR1) has also been reported in epithelial ... -
OSTEOPROTEGERIN PLASMA CONCENTRATIONS ARE CORRELATED WITH FORCED EXPIRATORY VOLUME AT 1 SECOND (FEV1) IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Mutlu, Levent Cem; Oran, Mustafa; Güzel, Savaş; Avcı, Okan; Yalçın, Banu Cicek; Küçükyalçın, Volkan (European Respiratory Soc Journals Ltd, 2013)[No Abstract Available] -
Osteoprotegerin Plasma Concentrations Are Correlated with Forced Expiratory Volume At 1 Second (Fev1) in Patients with Chronic Obstructive Pulmonary Disease
Mutlu, Levent Cem; Oran, Mustafa; Akyüz, Aydın; Güzel, Savaş; Topçu, Birol; Avcı, Okan; Küçükyalçın, Volkan (Carbone Editore, 2015)Introduction: Several inflammatory biomarkers such as 1L-1 beta, IL-6 and TNF-alpha have been evaluated during stable state and exacerbations of chronic obstructive pulmonary disease (COPD), Osteoprotegerin (OPG) is a ... -
Osteoprotegerin, leptin and IL-6: Association with silent myocardial ischemia in type 2 diabetes mellitus
Güzel, Savaş; Seven, Arzu; Kocaoglu, Ali; İlk, Banu; Güzel, Eda Çelik; Saraçoğlu Varol, Gamze; Çelebi, Asian (Sage Publications Ltd, 2013)Background: Diabetic patients often exhibit severe, asymptomatic coronary artery disease (CAD). The relationship between osteoprotegerin (OPG), inflammatory markers and silent myocardial ischemia remains to be elucidated. ... -
Protective effect of infliximab on ischemia/reperfusion injury in a rat ovary model: biochemical and histopathologic evaluation
Abalı, Remzi; Taşdemir, Nicel; Yüksel, Mehmet Aytaç; Güzel, Savaş; Öznur, Meltem; Nalbantoğlu, Burçin; Taşdemir, Ufuk Göker (Elsevier Science Bv, 2013)Objective: The aim of this study was to investigate the effect of infliximab on experimentally induced ovarian ischernia/reperfusion injury (IRi). Study design: A total of 42 female rats were equally divided into 6 ... -
Red Cell Distribution Width and Acute Complications of Diabetes
Atalay, Hande; Boyuk, B.; Ateş, Murat; Güzel, Savaş; Çelebi, A.; Ekizoğlu, İsmail (Editura Acad Romane, 2018)Context. Red cell distribution width (RDW) has been associated with type 2 diabetes (T2DM), however data in relation to diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar non-ketotic acidosis (HONK) remains unclear. ... -
Relationship between Levels of Brain-Derived Neurotrophic Factor and Metabolic Parameters in Patients with Type 2 Diabetes Mellitus
Boyuk, Banu; Değirmencioğlu, Şerife; Atalay, Hande; Güzel, Savaş; Acar, Ayşe; Çelebi, Aslan; Şimşek, Çağlar (Hindawi Ltd, 2014)Background and Aim. Studies have suggested that brain-derived neurotrophic factor (BDNF) plays a role in glucose and lipid metabolism and inflammation. The aim of this study was to evaluate the relationship between serum ... -
Relationship between Microfibrillar-Associated Protein 4 Levels and Subclinical Myocardial Damage in Chronic Kidney Disease
Kara, Sonat Pınar; Özkan, Gülsüm; Özkaramanlı Gür, Demet; Emeksiz, Gaye Kübra; Yılmaz, Ahsen; Bayrakçı, Nergiz; Güzel, Savaş (Karger, 2020)Introduction:Chronic kidney disease (CKD) is a widespread health problem, in which mortality is most frequently due to cardiovascular diseases. Microfibrillar-associated protein 4 (MFAP4) is an extracellular matrix protein. ... -
Relationship between plasma chemerin levels and disease severity in COPD patients
Boyuk, Banu; Güzel, Eda Çelik; Atalay, Hande; Güzel, Savaş; Mutlu, Levent Cem; Küçükyalçın, Volkan (Wiley, 2015)Background and AimsChronic inflammation of the lung is a characteristic finding in chronic obstructive pulmonary disease (COPD). The protein chemerin has been identified in inflammatory fluid and in inflamed tissues. This ... -
Relationship of serum salusin beta levels with coronary slow flow
Akyüz, Aydın; Aydın, Fatma; Alpsoy, Şeref; Özkaramanlı Gür, Demet; Güzel, Savaş (Aves, 2019)Objective: The pathophysiology of coronary slow flow (CSF) has not been clarified. Salusin-beta is released predominantly from the atheroma plaques and influences the pathophysiologic processes of atherosclerosis. Therefore, ...