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Toplam kayıt 11, listelenen: 1-10
Are the leading drugs against Staphylococcus aureus reallytoxic to cartilage?
(Elsevier Science London, 2016)
Many studies have shown that the toxic effects of local antibiotics on bone and cartilage limit orthopedic surgeons. In this study, we evaluated three antibacterial agents used locally to treat highly mortal and morbid ...
The association between different molecular weights of hyaluronic acid and CHAD, HIF-1 alpha, COL2A1 expression in chondrocyte cultures
(Spandidos Publ Ltd, 2018)
The aim of the present study was to investigate the effects of three different formulations of hyaluronic acid (HA): Low molecular weight (MW) Sinovial One((R)), medium MW Viscoplus((R)) and high MW Durolane((R)), on ...
Is it Possible to Treat Osteosarcoma Using Oligonucleotides Confined into Controlled Release Drug Delivery Systems?
(Bentham Science Publ Ltd, 2017)
Purpose: The present study aimed to analyze the researches that are at the experimental phase concerning osteosarcoma treatment. The researches included drug delivery systems which allow controlled release and imbue small ...
Are chondrocytes damaged when rheumatologic inflammation is suppressed?
(Taylor & Francis Ltd, 2017)
Aim: The use of biological agents (BAs) for treating diseases such as rheumatoid arthritis (RA), spondyloarthropathy, and systemic lupus erythematosus to reduce inflammation has been fruitful. Especially as part of the ...
Are biological agents toxic to human chondrocytes and osteocytes?
(Bmc, 2015)
Purpose: The aim of the present study is to investigate the effects of biological agents (BAs) on human chondrocytes and osteocytes in vitro. Methods: Primary cell cultures obtained from gonarthrosis patients were divided ...
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in septic arthritis
(Sage Publications Inc, 2015)
Is neutrophil-to-lymphocyte ratio high in patients with septic arthritis? Septic arthritis may lead to higher rates of morbidity or even mortality if not diagnosed on time. This study was planned to answer the question ...
Assessing the negative impact of phenyl alkanoic acid derivative, a frequently prescribed drug for the suppression of pain and inflammation, on the differentiation and proliferation of chondrocytes
(Bmc, 2016)
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed to relieve pain and inflammation. These NSAIDs have also analgesic effects and can be administered via oral, injectable, and topical ...
A practical way to prepare primer human chondrocyte culture
(Elsevier Science Bv, 2016)
Biological cartilage repair is one of themost important targets for orthopedic surgeons currently. For this purpose, it is mandatory to know how to prepare a chondrocyte culture. In this study, our purpose was to introduce ...
Iopromide - and gadopentetic acid-derived preparates used in MR arthrography may be harmful to chondrocytes
(Bmc, 2017)
Background: Magnetic resonance arthrography, a procedure through which contrast agents containing gadolinium and/or iopromide are administered intra-articularly, has become a useful tool in musculoskeletal diagnosis. ...
Does leukocyte-poor or leukocyte-rich platelet-rich plasma applied with biopolymers have superiority to conventional platelet-rich plasma applications on chondrocyte proliferation?
(Turkish Joint Diseases Foundation, 2017)
Objectives: This study aims to investigate the possible effects of leukocyte concentration in the content of platelet-rich plasma (PRP) and the administration of PRP using a drug delivery system on chondrocyte proliferation ...