Ara
Toplam kayıt 40, listelenen: 21-30
Evaluation of the expression and proliferation of degenerative markers in primary cell cultures obtained from human intervertebral disc tissue
(2020)
Aim: A major cause of low back pain is disc degeneration. Nevertheless, no specific and reliable markers of the degeneration of thenucleus pulposus (NP) are available. This presented study aimed to examine changes in the ...
Investigation of the effects of tigecycline, a semi-synthetic derivative of minocycline, on chondrocyte cultures
(2020)
AbstractAim: Although antibiotics are generally well-tolerated, they may have cytotoxic effects. The present randomized, double-blind, in vitro study aimed to investigate the effects of tigecycline on cartilage tissue cells ...
A Study on the Effects of Direct Factor Xa Inhibitors and Direct Thrombin Inhibitors on Human Primary Chondrocyte Cultures
(2019)
Aim:This study investigates the effects of two direct factor Xa inhibitors, apixaban and rivaroxaban, and a direct thrombin inhibitor, dabigatran, on human primary chondrocytecultures.Materials and Methods:Monolayer cultured ...
Evaluation of the effects of pregabalin on chondrocyte proliferation and CHAD, HIF-1 alpha, and COL2A1 gene expression
(Termedia Publishing House Ltd, 2018)
Introduction: The aim of the present study is to investigate the effects of pregabalin (PGB) on chondrocyte proliferation and collagen type II (COL2A1), hypoxia-inducible factor 1-alpha (HIF-1 alpha), and chondroadherin ...
Assessing the negative impact of phenyl alkanoic acid derivative, a frequently prescribed drug for the suppression of pain and inflammation, on the differentiation and proliferation of chondrocytes
(Bmc, 2016)
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed to relieve pain and inflammation. These NSAIDs have also analgesic effects and can be administered via oral, injectable, and topical ...
Yumurtalık Kanseri Hücre Soylarında CIP2A Onkogeni Mutasyonlarının Taranması
(2019)
Amaç: Kanserle ilişkili genetik değişimlerin belirlenmesi erken tanı, hastalığın takibi ve hedefe yöneliktedavi yaklaşımlarının geliştirilmesi açısından önem taşımaktadır. CIP2A, birçok insan kanserleri ileilişkilendirilmiş ...
A practical way to prepare primer human chondrocyte culture
(Elsevier Science Bv, 2016)
Biological cartilage repair is one of themost important targets for orthopedic surgeons currently. For this purpose, it is mandatory to know how to prepare a chondrocyte culture. In this study, our purpose was to introduce ...
Expression Profile of Transcription Factor ELK-1 and ELK-1 Target Genes on Lymphoma-Leukemia Cell Lines
(2018)
Prognostic molecular markers identified in leukemia are becomingincreasingly important especially in risk stratification and to determine therapy. Inthis study, we investigate the role of ELK-1 transcription factor and its ...
Biyopolimerler ile uygulanan lökositten fakir veya lökositten zengin trombositten zengin plazmanın kondrosit proliferasyonunda konvansiyonel trombositten zengin plazma uygulamalarına üstünlüğü var mıdır?
(2017)
Amaç: Bu çalışmada trombositten zengin plazma (TZP) içeriğindeki lökosit konsantrasyonunun ve TZP'nin ilaç taşıyıcı sistem kullanılarak uygulanmasının in vitro koşullarda kondrosit proliferasyonu üzerine olası etkileri ...
Chondrocyte proliferation, viability and differentiation is declined following administration of methylphenidate utilized for the treatment of attention-deficit/hyperactivity disorder
(Sage Publications Ltd, 2017)
Purpose: Methylphenidate (MPH) derivative drugs are used because of psychostimulants effects on attention-deficit hyperactivity disorder in children and adults. As far as we know, toxic or anti-proliferative effects of MPH ...